AutismKB 2.0

Annotation Detail for MVP


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MVP ( LRP,VAULT1 )
Gene Full Name: major vault protein
Band: 16p11.2
Quick LinksEntrez ID:9961; OMIM: 605088; Uniprot ID:MVP_HUMAN; ENSEMBL ID: ENSG00000013364; HGNC ID: 7531
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
13Phosphotyrosine.
15Phosphotyrosine.
Location(AA) Modifications Resource
2N-acetylalanine.Swiss-Prot 53.0
12PhosphotyrosinePhospho.ELM 6.0
13Phosphotyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
24N-linkedHMM predict
389Phosphotyrosine(EGFR)HMM predict
389SulfotyrosineHMM predict
453N-linkedHMM predict
864Phosphoserine(PKB)HMM predict
864PhosphoserineHMM predict
867Phosphoserine(ATM)HMM predict
873O-linkedHMM predict
873Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017458
  • Location:chr16 29739288-29766841
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 29757069 29757159 90 0
H3ac HepG2E 29739334 29741463 2129 0
H3ac HepG2E 29745783 29746270 487 0
TFAP2C MCF7GSE21234 29739817 29740533 716 0
USF1 HepG2E 29739270 29741521 2251 0
USF1 HepG2E 29745783 29746270 487 0
USF1 HepG2E 29748306 29749583 1277 0
USF2 HepG2E 29748306 29749019 713 0
p130 SenescentGSE19898 29744213 29744589 376 0
p130 shRbQuiescentGSE19898 29739890 29740830 940 0
p130 shRbSenescentGSE19898 29744476 29744722 246 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018