Evidence Details for TSHZ1
Basic Information Top
| Gene Symbol: | TSHZ1 ( NY-CO-33,SDCCAG33,TSH1 ) |
|---|---|
| Gene Full Name: | teashirt zinc finger homeobox 1 |
| Band: | 18q22.3 |
| Quick Links | Entrez ID:10194; OMIM: NA; Uniprot ID:TSH1_HUMAN; ENSEMBL ID: ENSG00000179981; HGNC ID: 10669 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>TSHZ1|10194|nucleotide
ATGTGCAATGAAGAGACGGAGATCAAAGAGGCGCAGAGCTACCAGAACTCCCCAGTCAGCTCTGCGACTAACCAGGACGCCGGCTACGGGTCGCCCTTCAGTGAG
AGCAGCGACCAGCTAGCCCATTTCAAAGGCTCTTCCTCTCGAGAAGAGAAGGAGGATCCGCAGTGTCCCGACAGCGTCTCGTACCCCCAGGACAGCCTGGCACAG
ATCAAAGCTGTGTATGCAAACTTGTTCTCCGAGTCCTGCTGGTCCAGCTTAGCTCTGGATTTAAAGAAGTCGGGTTCCACCACCAGCACCAACGATGCCAGCCAG
AAGGAGAGCTCCGCCCCCACCCCCACACCCCCCACCTGCCCCGTCAGCACCACTGGCCCCACCACGAGCACGCCCAGCACCAGCTGCAGCTCCAGCACCAGCCAC
AGCAGTACCACCAGTACCAGCAGCAGCTCCGGGTACGACTGGCACCAGGCTGCACTGGCCAAGACGCTGCAGCAGACGTCCTCGTATGGGCTGCTTCCTGAGCCC
AGCCTGTTCAGCACCGTGCAGCTCTACCGCCAGAACAACAAGCTCTACGGCTCCGTCTTCACGGGCGCCAGCAAGTTCCGGTGCAAAGACTGCAGTGCCGCGTAC
GACACGCTGGTGGAACTGACGGTGCACATGAACGAGACAGGCCACTACCGTGACGACAACAGGGACAAGGACTCCGAGAAGACCAAGAGGTGGTCCAAGCCCAGG
AAGCGCTCCCTGATGGAGATGGAGGGGAAGGAGGATGCCCAGAAGGTGCTGAAGTGCATGTACTGTGGACACTCCTTTGAGTCCTTGCAGGACCTCAGCGTCCAC
ATGATCAAAACCAAGCATTACCAGAAAGTGCCTCTGAAGGAGCCAGTGCCAGCCATCACCAAACTGGTCCCCTCCACCAAAAAGCGGGCGCTTCAGGACCTGGCG
CCCCCCTGCTCCCCTGAGCCAGCAGGAATGGCCGCAGAGGTGGCCCTGAGTGAGTCAGCCAAGGATCAGAAAGCAGCGAACCCGTACGTCACGCCCAATAACCGC
TATGGCTACCAGAATGGCGCCAGCTACACCTGGCAGTTTGAGGCCCGCAAGGCGCAGATCCTCAAGTGCATGGAGTGTGGCAGCTCCCACGACACGCTGCAGCAG
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ATGTGCAATGAAGAGACGGAGATCAAAGAGGCGCAGAGCTACCAGAACTCCCCAGTCAGCTCTGCGACTAACCAGGACGCCGGCTACGGGTCGCCCTTCAGTGAG
AGCAGCGACCAGCTAGCCCATTTCAAAGGCTCTTCCTCTCGAGAAGAGAAGGAGGATCCGCAGTGTCCCGACAGCGTCTCGTACCCCCAGGACAGCCTGGCACAG
ATCAAAGCTGTGTATGCAAACTTGTTCTCCGAGTCCTGCTGGTCCAGCTTAGCTCTGGATTTAAAGAAGTCGGGTTCCACCACCAGCACCAACGATGCCAGCCAG
AAGGAGAGCTCCGCCCCCACCCCCACACCCCCCACCTGCCCCGTCAGCACCACTGGCCCCACCACGAGCACGCCCAGCACCAGCTGCAGCTCCAGCACCAGCCAC
AGCAGTACCACCAGTACCAGCAGCAGCTCCGGGTACGACTGGCACCAGGCTGCACTGGCCAAGACGCTGCAGCAGACGTCCTCGTATGGGCTGCTTCCTGAGCCC
AGCCTGTTCAGCACCGTGCAGCTCTACCGCCAGAACAACAAGCTCTACGGCTCCGTCTTCACGGGCGCCAGCAAGTTCCGGTGCAAAGACTGCAGTGCCGCGTAC
GACACGCTGGTGGAACTGACGGTGCACATGAACGAGACAGGCCACTACCGTGACGACAACAGGGACAAGGACTCCGAGAAGACCAAGAGGTGGTCCAAGCCCAGG
AAGCGCTCCCTGATGGAGATGGAGGGGAAGGAGGATGCCCAGAAGGTGCTGAAGTGCATGTACTGTGGACACTCCTTTGAGTCCTTGCAGGACCTCAGCGTCCAC
ATGATCAAAACCAAGCATTACCAGAAAGTGCCTCTGAAGGAGCCAGTGCCAGCCATCACCAAACTGGTCCCCTCCACCAAAAAGCGGGCGCTTCAGGACCTGGCG
CCCCCCTGCTCCCCTGAGCCAGCAGGAATGGCCGCAGAGGTGGCCCTGAGTGAGTCAGCCAAGGATCAGAAAGCAGCGAACCCGTACGTCACGCCCAATAACCGC
TATGGCTACCAGAATGGCGCCAGCTACACCTGGCAGTTTGAGGCCCGCAAGGCGCAGATCCTCAAGTGCATGGAGTGTGGCAGCTCCCACGACACGCTGCAGCAG
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>TSHZ1|10194|protein
MCNEETEIKEAQSYQNSPVSSATNQDAGYGSPFSESSDQLAHFKGSSSREEKEDPQCPDSVSYPQDSLAQIKAVYANLFSESCWSSLALDLKKSGSTTSTNDASQ
KESSAPTPTPPTCPVSTTGPTTSTPSTSCSSSTSHSSTTSTSSSSGYDWHQAALAKTLQQTSSYGLLPEPSLFSTVQLYRQNNKLYGSVFTGASKFRCKDCSAAY
DTLVELTVHMNETGHYRDDNRDKDSEKTKRWSKPRKRSLMEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVPAITKLVPSTKKRALQDLA
PPCSPEPAGMAAEVALSESAKDQKAANPYVTPNNRYGYQNGASYTWQFEARKAQILKCMECGSSHDTLQQLTAHMMVTGHFLKVTTSASKKGKQLVLDPVVEEKI
QSIPLPPTTHTRLPASSIKKQPDSPAGSTTSEEKKEPEKEKPPVAGDAEKIKEESEDSLEKFEPSTLYPYLREEDLDDSPKGGLDILKSLENTVSTAISKAQNGA
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MCNEETEIKEAQSYQNSPVSSATNQDAGYGSPFSESSDQLAHFKGSSSREEKEDPQCPDSVSYPQDSLAQIKAVYANLFSESCWSSLALDLKKSGSTTSTNDASQ
KESSAPTPTPPTCPVSTTGPTTSTPSTSCSSSTSHSSTTSTSSSSGYDWHQAALAKTLQQTSSYGLLPEPSLFSTVQLYRQNNKLYGSVFTGASKFRCKDCSAAY
DTLVELTVHMNETGHYRDDNRDKDSEKTKRWSKPRKRSLMEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVPAITKLVPSTKKRALQDLA
PPCSPEPAGMAAEVALSESAKDQKAANPYVTPNNRYGYQNGASYTWQFEARKAQILKCMECGSSHDTLQQLTAHMMVTGHFLKVTTSASKKGKQLVLDPVVEEKI
QSIPLPPTTHTRLPASSIKKQPDSPAGSTTSEEKKEPEKEKPPVAGDAEKIKEESEDSLEKFEPSTLYPYLREEDLDDSPKGGLDILKSLENTVSTAISKAQNGA
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (2) | 0 (3) | 0 (0) | 0 (0) | 0 (0) | 0 (2) | 0 (0) | 0 (0) | 0 (0) | 0 (7) |
Syndromic Autism Gene TopGenome-Wide Association Studies (By Ethnic Group) Top Family Based Association Studies: 2
| Reference | Stage | Platform | #Families | Affecteds | Result | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ (range) |
||||||
| CAUCASIAN | |||||||||||
| Salyakina, 2010_2 | Replication | Illumina HumanHap 550K BeadChip | 110 | - (-) |  |  | AS | - (3-21) |
- >70 | ||
| Salyakina, 2010_1 | Discovery | Illumina HumanHap 550K BeadChip | 124 | - (-) | | | AS | - (3-21) |
- >70 | ||
Case Control Based Association Studies: 0
| Reference | Stage | Platform | ASD Cases | Normal Controls | Result | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ | #Subjects (% Women) |
Age (range) |
|||||
| No Evidence. | ||||||||||||
CNV Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Marshall, 2008 | - | SNP microarray | | | ASD | 427 | 238 | 189 | - | 427 | 500 | 927 |
| Bremer, 2011 | - | aCGH | | | ASD | - | - | - | - | 223 | - | 223 |
| Sanders, 2011 | Simons Simplex Collection | SNP microarray | - | - | ASD | 1127 | 1127 | - | - | - | - | - |
Linkage Studies Top