Evidence Details for TOB2
Basic Information Top
| Gene Symbol: | TOB2 ( TOB4,TOBL,TROB2 ) |
|---|---|
| Gene Full Name: | transducer of ERBB2, 2 |
| Band: | 22q13.2 |
| Quick Links | Entrez ID:10766; OMIM: 607396; Uniprot ID:TOB2_HUMAN; ENSEMBL ID: ENSG00000183864; HGNC ID: 11980 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>TOB2|10766|nucleotide
ATGCAGCTAGAGATCAAAGTGGCCCTGAACTTCATCATCTCCTACTTGTACAACAAGCTGCCCCGGCGCCGGGCAGACCTGTTTGGGGAGGAGCTAGAGCGGCTT
TTGAAAAAGAAATATGAAGGCCACTGGTACCCTGAGAAGCCACTGAAAGGCTCTGGCTTCCGCTGTGTTCACATTGGGGAGATGGTGGACCCCGTGGTGGAGCTG
GCCGCCAAGCGGAGTGGCCTGGCGGTGGAAGATGTGCGGGCCAATGTGCCTGAGGAGCTGAGTGTCTGGATTGATCCCTTTGAGGTGTCCTACCAGATTGGTGAG
AAGGGAGCTGTGAAAGTGCTGTACCTGGATGACAGTGAGGGTTGCGGTGCCCCAGAGCTGGACAAGGAGATCAAGAGCAGCTTCAACCCTGACGCCCAGGTGTTC
GTGCCCATTGGCAGCCAGGACAGCTCCCTGTCCAACTCCCCATCGCCATCCTTTGGCCAGTCACCCAGCCCTACCTTCATTCCCCGCTCCGCTCAGCCCATCACC
TTCACCACCGCCTCCTTCGCTGCCACCAAATTTGGCTCCACTAAGATGAAGAAGGGGGGCGGGGCAGCAAGTGGTGGGGGTGTAGCCAGCAGTGGGGCGGGTGGC
CAGCAGCCACCACAGCAGCCTCGCATGGCCCGCTCACCCACCAACAGCCTGCTGAAGCACAAGAGCCTCTCTCTGTCTATGCATTCACTGAACTTCATCACGGCC
AACCCGGCCCCTCAGTCCCAGCTCTCACCCAATGCCAAGGAGTTCGTGTACAACGGTGGTGGCTCACCCAGCCTCTTCTTTGATGCGGCCGATGGCCAGGGCAGC
GGCACCCCAGGCCCGTTTGGAGGCAGTGGGGCTGGCACCTGCAACAGCAGCAGCTTTGACATGGCCCAGGTATTTGGAGGTGGTGCCAACAGCCTCTTCCTGGAG
AAGACACCCTTTGTGGAAGGCCTCAGCTACAACCTGAACACCATGCAGTATCCCAGCCAGCAGTTCCAGCCCGTGGTGCTGGCCAACTGA
Show »
ATGCAGCTAGAGATCAAAGTGGCCCTGAACTTCATCATCTCCTACTTGTACAACAAGCTGCCCCGGCGCCGGGCAGACCTGTTTGGGGAGGAGCTAGAGCGGCTT
TTGAAAAAGAAATATGAAGGCCACTGGTACCCTGAGAAGCCACTGAAAGGCTCTGGCTTCCGCTGTGTTCACATTGGGGAGATGGTGGACCCCGTGGTGGAGCTG
GCCGCCAAGCGGAGTGGCCTGGCGGTGGAAGATGTGCGGGCCAATGTGCCTGAGGAGCTGAGTGTCTGGATTGATCCCTTTGAGGTGTCCTACCAGATTGGTGAG
AAGGGAGCTGTGAAAGTGCTGTACCTGGATGACAGTGAGGGTTGCGGTGCCCCAGAGCTGGACAAGGAGATCAAGAGCAGCTTCAACCCTGACGCCCAGGTGTTC
GTGCCCATTGGCAGCCAGGACAGCTCCCTGTCCAACTCCCCATCGCCATCCTTTGGCCAGTCACCCAGCCCTACCTTCATTCCCCGCTCCGCTCAGCCCATCACC
TTCACCACCGCCTCCTTCGCTGCCACCAAATTTGGCTCCACTAAGATGAAGAAGGGGGGCGGGGCAGCAAGTGGTGGGGGTGTAGCCAGCAGTGGGGCGGGTGGC
CAGCAGCCACCACAGCAGCCTCGCATGGCCCGCTCACCCACCAACAGCCTGCTGAAGCACAAGAGCCTCTCTCTGTCTATGCATTCACTGAACTTCATCACGGCC
AACCCGGCCCCTCAGTCCCAGCTCTCACCCAATGCCAAGGAGTTCGTGTACAACGGTGGTGGCTCACCCAGCCTCTTCTTTGATGCGGCCGATGGCCAGGGCAGC
GGCACCCCAGGCCCGTTTGGAGGCAGTGGGGCTGGCACCTGCAACAGCAGCAGCTTTGACATGGCCCAGGTATTTGGAGGTGGTGCCAACAGCCTCTTCCTGGAG
AAGACACCCTTTGTGGAAGGCCTCAGCTACAACCTGAACACCATGCAGTATCCCAGCCAGCAGTTCCAGCCCGTGGTGCTGGCCAACTGA
Show »
>TOB2|10766|protein
MQLEIKVALNFIISYLYNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCVHIGEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGE
KGAVKVLYLDDSEGCGAPELDKEIKSSFNPDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAASGGGVASSGAGG
QQPPQQPRMARSPTNSLLKHKSLSLSMHSLNFITANPAPQSQLSPNAKEFVYNGGGSPSLFFDAADGQGSGTPGPFGGSGAGTCNSSSFDMAQVFGGGANSLFLE
KTPFVEGLSYNLNTMQYPSQQFQPVVLAN
Show »
MQLEIKVALNFIISYLYNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCVHIGEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGE
KGAVKVLYLDDSEGCGAPELDKEIKSSFNPDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAASGGGVASSGAGG
QQPPQQPRMARSPTNSLLKHKSLSLSMHSLNFITANPAPQSQLSPNAKEFVYNGGGSPSLFFDAADGQGSGTPGPFGGSGAGTCNSSSFDMAQVFGGGANSLFLE
KTPFVEGLSYNLNTMQYPSQQFQPVVLAN
Show »
Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (0) | 1 (3) | 0 (0) | 0 (0) | 0 (0) | 0 (1) | 0 (0) | 0 (0) | 0 (0) | 2 (4) |
Syndromic Autism Gene TopGenome-Wide Association Studies(By Ethnic Group) TopCNV Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Prasad, 2000 | - | FISH |  | | autism | - | - | - | - | 1 | - | 1 |
| Wassink, 2001 | USA | Chromosomal analysis of G-band | | | autism | - | - | - | - | 278 | - | 278 |
| Zwaag, 2009 | - | SNP microarray |  | | autism | - | - | - | - | 105 | 267 | 372 |
Linkage Studies Top