Evidence Details for RASGRP4

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Basic Information Top

Gene Symbol:	RASGRP4 ( - )
Gene Full Name:	RAS guanyl releasing protein 4
Band:	19q13.1
Quick Links	Entrez ID:115727; OMIM: 607320; Uniprot ID:GRP4_HUMAN; ENSEMBL ID: ENSG00000171777; HGNC ID: 18958
Relate to Another Database:	SFARIGene; denovo-db

Sequences Top

Nucleotide Sequence
Protein Sequence

>RASGRP4|115727|nucleotide
ATGAACAGAAAAGACAGTAAGAGGAAGTCCCACCAGGAATGCACCGGAAAAATAGGAGGGCGAGGCCGGCCCCGCCAAGTGCGCCGCCACAAGACATGCCCCAGC
CCTCGGGAAATCAGCAAGGTCATGGCTTCCATGAACCTGGGCCTGCTGAGTGAGGGCGGCTGCAGCGAAGATGAGCTGCTGGAGAAATGCATCCAGTCCTTCGAT
TCAGCTGGCAGCCTGTGCCACGAGGACCACATGCTCAACATGGTGCTGGCCATGCACAGCTGGGTGCTGCCGTCCGCCGACCTGGCTGCCCGCCTGCTGACCTCA
TACCAGAAGGCCACAGGGGACACCCAGGAGCTGAGACGGCTGCAGATCTGTCACCTGGTCAGGTACTGGCTGATGCGACACCCTGAGGTGATGCACCAGGATCCC
CAGCTAGAAGAAGTCATAGGTCGTTTCTGGGCCACCGTGGCCCGGGAGGGCAACTCAGCCCAGAGAAGACTGGGAGACTCTTCTGACCTCCCAGGCCTGGGCAAA
AAGCGCAAAGTGTCCTTGCTTTTCGACCACTTGGAGACGGGGGAGCTGGCTCAGCACCTCACCTACCTGGAGTTCCGGTCCTTCCAGGCTATCACGCCCCAGGAC
CTGCGGAGCTACGTTTTGCAGGGCTCAGTACGAGGCTGCCCGGCCCTGGAGGGCTCCGTAGGTCTCAGCAACAGCGTGTCCCGCTGGGTGCAGGTGATGGTGCTG
AGCCGTCCCGGGCCCCTACAGCGTGCACAGGTGCTGGACAAGTTCATTCACGTGGCACAGAGGCTCCACCAGCTGCAGAATTTCAACACGCTGATGGCAGTCACA
GGGGGCCTGTGTCACAGTGCCATCTCCAGACTCAAGGACTCCCATGCCCACCTGAGCCCTGACAGCACCAAGGCCCTCCTGGAGCTCACTGAGCTCCTTGCCTCC
CACAACAACTACGCCCGCTACCGCCGCACCTGGGCTGGCTGCGCGGGTTTCCGGCTGCCTGTACTGGGCGTGCACCTCAAGGACCTGGTGTCCCTGCATGAGGCA
CAGCCCGACAGGTTGCCTGACGGCCGCCTGCACCTACCCAAGCTGAACAACCTCTACCTGCGGCTGCAGGAGCTGGTGGCCCTCCAAGGGCAGCATCCACCCTGC
AGCGCCAATGAGGATCTGCTGCACCTGCTCACGCTCTCCCTGGACCTCTTCTACACGGAAGACGAGATCTATGAGCTTTCTTATGCCCGGGAGCCGCGTTGTCCC
AAGAGCCTGCCACCCTCCCCCTTCAATGCACCTCTGGTGGTGGAGTGGGCCCCTGGTGTGACACCCAAGCCGGACAGGGTCACACTGGGTCGGCATGTGGAGCAG
CTGGTGGAGTCTGTGTTCAAGAATTATGACCCTGAAGGCCGAGGAACAATCTCTCAGGAGGACTTTGAGCGACTCTCGGGCAATTTTCCCTTCGCCTGCCATGGG
CTTCACCCACCCCCACGCCAGGGGAGAGGATCCTTCAGCAGAGAGGAGCTGACAGGGTACCTGCTCCGGGCCAGCGCCATCTGCTCCAAGTTGGGCCTGGCCTTC
CTGCACACCTTCCATGAGGTCACCTTCCGAAAGCCTACCTTCTGCGACAGCTGCAGTGGCTTCCTCTGGGGTGTCACCAAGCAAGGCTACCGCTGTCGGGAGTGC
GGGCTGTGTTGCCACAAACACTGCAGAGACCAGGTGAAGGTAGAATGTAAGAAGAGGCCAGGGGCCAAGGGCGATGCAGGACCCCCCGGAGCTCCTGTCCCATCC
ACACCAGCTCCCCATGCCAGCTGTGGCTCCGAGGAAAATCACTCCTACACGCTATCCCTGGAGCCTGAGACTGGGTGCCAGCTTCGCCATGCCTGGACCCAGACT
GAATCCCCACACCCTTCCTGGGAAACAGATACGGTCCCCTGCCCGGTGATGGACCCACCATCAACTGCATCCTCCAAGCTGGATTCCTAG
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Evidence summary Top

Click the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.

Evidences	Syndromic Gene	GWAS	CNV	Linkage	Association	Expression	NGS de novo	NGS Mosaic	NGS Other	Low-Scale Gene Studies	Total
Score (No. of Studies)	No	0 (2)	1 (1)	0 (0)	0 (0)	0 (0)	0 (1)	0 (0)	0 (0)	0 (0)	2 (4)

Syndromic Autism Gene Top

Genome-Wide Association Studies (By Ethnic Group) Top

Family Based Association Studies: 2

Reference	Stage	Platform	#Families	Affecteds						Result
Reference	Stage	Platform	#Families	#Subjects (% Women)	ADI-R	ADOS	Diagnosis	Age (range)	IQ (range)	Result
CAUCASIAN
Salyakina, 2010_2	Replication	Illumina HumanHap 550K BeadChip	110	- (-)			AS	- (3-21)	- >70
Salyakina, 2010_1	Discovery	Illumina HumanHap 550K BeadChip	124	- (-)			AS	- (3-21)	- >70

Case Control Based Association Studies: 0

Reference	Stage	Platform	ASD Cases						Normal Controls		Result
Reference	Stage	Platform	#Subjects (% Women)	ADI-R	ADOS	Diagnosis	Age (range)	IQ	#Subjects (% Women)	Age (range)	Result
No Evidence.

CNV Studies Top

Reference	Source	Method	ADI-R	ADOS	Diagnosis	Family				Individual
Reference	Source	Method	ADI-R	ADOS	Diagnosis	Total	Simplex	Multiplex	Control	Affected	Control	Total
Zwaag, 2009	-	SNP microarray			autism	-	-	-	-	105	267	372

Linkage Studies Top

AutismKB 2.0

Evidence Details for RASGRP4