Evidence Details for DLX4
Basic Information Top
| Gene Symbol: | DLX4 ( BP1,DLX7,DLX8,DLX9 ) |
|---|---|
| Gene Full Name: | distal-less homeobox 4 |
| Band: | 17q21.33 |
| Quick Links | Entrez ID:1748; OMIM: 601911; Uniprot ID:DLX4_HUMAN; ENSEMBL ID: ENSG00000108813; HGNC ID: 2917 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>DLX4|1748|nucleotide
ATGAAACTGTCCGTCCTACCCCCTCGCTCCCTCCTCGCCCCCTACACCGTGTTGTGCTGCCCACCAGACTCGGAGAAGCCGCGGCTGTCCCCGGAACCCTCCGAG
CGGCGCCCTCAGGCCCCCGCCAAAAAGCTCCGCAAGCCGAGGACCATCTACTCCAGCCTGCAGCTGCAGCACCTAAACCAGCGTTTCCAGCACACGCAGTACCTG
GCGCTGCCCGAGAGGGCCCAGCTGGCAGCGCAGCTCGGCCTCACCCAGACCCAGGTAAAGATCTGGTTTCAGAACAAACGCTCCAAGTATAAGAAGCTCCTGAAG
CAGAATTCTGGGGGGCAGGAAGGGGACTTCCCTGGGAGGACCTTCTCTGTGTCTCCCTGCTCCCCACCCCTCCCCTCCCTCTGGGATCTACCCAAGGCAGGGACC
CTGCCCACCAGTGGCTATGGCAACAGCTTTGGAGCCTGGTATCAGCATCACTCCTCAGATGTCCTGGCTTCGCCTCAGATGATGTGA
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ATGAAACTGTCCGTCCTACCCCCTCGCTCCCTCCTCGCCCCCTACACCGTGTTGTGCTGCCCACCAGACTCGGAGAAGCCGCGGCTGTCCCCGGAACCCTCCGAG
CGGCGCCCTCAGGCCCCCGCCAAAAAGCTCCGCAAGCCGAGGACCATCTACTCCAGCCTGCAGCTGCAGCACCTAAACCAGCGTTTCCAGCACACGCAGTACCTG
GCGCTGCCCGAGAGGGCCCAGCTGGCAGCGCAGCTCGGCCTCACCCAGACCCAGGTAAAGATCTGGTTTCAGAACAAACGCTCCAAGTATAAGAAGCTCCTGAAG
CAGAATTCTGGGGGGCAGGAAGGGGACTTCCCTGGGAGGACCTTCTCTGTGTCTCCCTGCTCCCCACCCCTCCCCTCCCTCTGGGATCTACCCAAGGCAGGGACC
CTGCCCACCAGTGGCTATGGCAACAGCTTTGGAGCCTGGTATCAGCATCACTCCTCAGATGTCCTGGCTTCGCCTCAGATGATGTGA
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>DLX4|1748|protein
MKLSVLPPRSLLAPYTVLCCPPDSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLK
QNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM
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MKLSVLPPRSLLAPYTVLCCPPDSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLK
QNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (0) | 0 (0) | 0 (0) | 0 (2) | 0 (0) | 0 (1) | 0 (0) | 0 (0) | 0 (0) | 0 (3) |
Syndromic Autism Gene TopGenome-Wide Association Studies(By Ethnic Group) TopCNV Studies TopLinkage Studies TopLow Scale Association Studies (by Ethnic Group) Top Family Based Association Studies: 2
| Reference | Source | Platform | #Families | Affecteds | Result | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ (range) |
|||||
| CAUCASIAN | ||||||||||
| Chang, 2010_1 | USA | the Sequenom iPLEX platform | 715 | 1372 (20.00%) |  | | ASD | - - |
- - | |
| MIXED/OTHERS | ||||||||||
| Chang, 2011_1 | USA | Affymetrix | 715 | 1372 (20.00%) | | | ASD | - - |
- - | |
Case Control Based Association Studies: 0
| Reference | Source | Platfrom | ASD Cases | Normal Controls | Result | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| ADI-R | ADOS | Diagnosis | Age (range) |
IQ | #Subjects (% Women) |
Age (range) |
|||||
| No Evidence. | |||||||||||
Large Scale Expression Studies TopNGS de novo Mutation Studies Top| Reference | Case Number | Family Number | de novo Number | Title |
|---|---|---|---|---|
| De Rubeis S, 2014 | 2270 | - | 1702 | Synaptic, transcriptional and chromatin genes disrupted in autism |
NGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.