Evidence Details for DSPP
Basic Information Top
| Gene Symbol: | DSPP ( DFNA39,DGI1,DMP3,DPP,DSP,DTDP2 ) |
|---|---|
| Gene Full Name: | dentin sialophosphoprotein |
| Band: | 4q22.1 |
| Quick Links | Entrez ID:1834; OMIM: 125485; Uniprot ID:DSPP_HUMAN; ENSEMBL ID: ENSG00000152591; HGNC ID: 3054 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>DSPP|1834|nucleotide
ATGAAGATAATTACATATTTTTGCATTTGGGCAGTAGCATGGGCCATTCCAGTTCCTCAAAGCAAACCACTGGAGAGACATGTCGAAAAATCCATGAATTTGCAT
CTCCTAGCAAGATCAAATGTGTCAGTACAGGATGAGTTAAATGCCAGTGGAACCATCAAAGAAAGTGGTGTCCTGGTGCATGAAGGTGATAGAGGAAGGCAAGAG
AATACCCAAGATGGTCACAAGGGAGAAGGGAATGGCTCTAAGTGGGCAGAAGTAGGAGGGAAGAGTTTTTCTACATATTCCACATTAGCAAACGAAGAGGGGAAT
ATTGAGGGCTGGAATGGGGACACAGGAAAAGCAGAAACATATGGTCATGATGGAATACATGGGAAAGAAGAAAACATCACAGCAAATGGCATCCAGGGACAAGTA
AGCATCATTGACAATGCTGGAGCCACAAACAGAAGCAACACTAATGGAAATACTGATAAGAATACCCAAAATGGGGATGTTGGCGATGCAGGTCACAATGAGGAT
GTCGCTGTTGTCCAAGAAGATGGACCTCAAGTAGCTGGAAGCAATAACAGTACAGACAATGAGGATGAAATAATTGAGAATTCCTGTAGAAACGAGGGTAATACA
AGTGAAATAACACCTCAGATCAACAGCAAGAGAAATGGGACTAAGGAAGCTGAGGTAACACCAGGCACTGGAGAAGATGCTGGCCTGGATAATTCCGATGGGAGT
CCTAGTGGGAATGGAGCAGATGAGGATGAAGACGAGGGTTCTGGTGATGATGAAGATGAAGAAGCAGGGAATGGAAAAGACAGTAGTAATAACAGCAAGGGCCAG
GAGGGCCAGGACCATGGGAAAGAAGATGATCATGATAGTAGCATAGGTCAAAATTCAGATAGTAAAGAATATTATGACCCTGAAGGCAAAGAAGATCCCCATAAT
GAAGTTGATGGAGACAAGACCTCCAAGAGTGAGGAGAATTCTGCTGGTATTCCAGAAGACAATGGCAGCCAAAGAATAGAGGACACCCAGAAGCTCAACCATAGA
GAAAGCAAACGCGTAGAAAATAGAATCACCAAAGAATCAGAGACACATGCTGTTGGGAAGAGCCAAGATAAGGGAATAGAAATCAAGGGTCCCAGCAGTGGCAAC
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ATGAAGATAATTACATATTTTTGCATTTGGGCAGTAGCATGGGCCATTCCAGTTCCTCAAAGCAAACCACTGGAGAGACATGTCGAAAAATCCATGAATTTGCAT
CTCCTAGCAAGATCAAATGTGTCAGTACAGGATGAGTTAAATGCCAGTGGAACCATCAAAGAAAGTGGTGTCCTGGTGCATGAAGGTGATAGAGGAAGGCAAGAG
AATACCCAAGATGGTCACAAGGGAGAAGGGAATGGCTCTAAGTGGGCAGAAGTAGGAGGGAAGAGTTTTTCTACATATTCCACATTAGCAAACGAAGAGGGGAAT
ATTGAGGGCTGGAATGGGGACACAGGAAAAGCAGAAACATATGGTCATGATGGAATACATGGGAAAGAAGAAAACATCACAGCAAATGGCATCCAGGGACAAGTA
AGCATCATTGACAATGCTGGAGCCACAAACAGAAGCAACACTAATGGAAATACTGATAAGAATACCCAAAATGGGGATGTTGGCGATGCAGGTCACAATGAGGAT
GTCGCTGTTGTCCAAGAAGATGGACCTCAAGTAGCTGGAAGCAATAACAGTACAGACAATGAGGATGAAATAATTGAGAATTCCTGTAGAAACGAGGGTAATACA
AGTGAAATAACACCTCAGATCAACAGCAAGAGAAATGGGACTAAGGAAGCTGAGGTAACACCAGGCACTGGAGAAGATGCTGGCCTGGATAATTCCGATGGGAGT
CCTAGTGGGAATGGAGCAGATGAGGATGAAGACGAGGGTTCTGGTGATGATGAAGATGAAGAAGCAGGGAATGGAAAAGACAGTAGTAATAACAGCAAGGGCCAG
GAGGGCCAGGACCATGGGAAAGAAGATGATCATGATAGTAGCATAGGTCAAAATTCAGATAGTAAAGAATATTATGACCCTGAAGGCAAAGAAGATCCCCATAAT
GAAGTTGATGGAGACAAGACCTCCAAGAGTGAGGAGAATTCTGCTGGTATTCCAGAAGACAATGGCAGCCAAAGAATAGAGGACACCCAGAAGCTCAACCATAGA
GAAAGCAAACGCGTAGAAAATAGAATCACCAAAGAATCAGAGACACATGCTGTTGGGAAGAGCCAAGATAAGGGAATAGAAATCAAGGGTCCCAGCAGTGGCAAC
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>DSPP|1834|protein
MKIITYFCIWAVAWAIPVPQSKPLERHVEKSMNLHLLARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVGGKSFSTYSTLANEEGN
IEGWNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNT
SEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHN
EVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEV
VNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSD
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MKIITYFCIWAVAWAIPVPQSKPLERHVEKSMNLHLLARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVGGKSFSTYSTLANEEGN
IEGWNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNT
SEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHN
EVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEV
VNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSD
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (1) | 0 (1) | 1 (1) | 0 (0) | 0 (0) | 0 (1) | 0 (0) | 0 (0) | 0 (0) | 2 (4) |
Syndromic Autism Gene TopGenome-Wide Association Studies (By Ethnic Group) Top Family Based Association Studies: 1
| Reference | Stage | Platform | #Families | Affecteds | Result | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ (range) |
||||||
| CAUCASIAN | |||||||||||
| Hussman, 2011_1 | Discovery | Illumina Infinium Human 1 M beadship | 597 | - (-) |  |  | ASD | - - |
- - | ||
Case Control Based Association Studies: 0
| Reference | Stage | Platform | ASD Cases | Normal Controls | Result | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ | #Subjects (% Women) |
Age (range) |
|||||
| No Evidence. | ||||||||||||
CNV Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Jacquemont, 2006 | France | aCGH | | | ASD | - | - | - | - | 29 | - | 29 |
Linkage Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Yonan, 2003 | USA | microsatellite-based genomic screen | | | PDD | 345 | - | 345 | - | - | - | - |
Low Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies TopNGS de novo Mutation Studies Top| Reference | Case Number | Family Number | de novo Number | Title |
|---|---|---|---|---|
| Iossifov I, 2014 | 2508 | - | 1194 | The contribution of de novo coding mutations to autism spectrum disorder. |
NGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.