Evidence Details for NCOA6
Basic Information Top
| Gene Symbol: | NCOA6 ( AIB3,ASC2,KIAA0181,NRC,PRIP,RAP250,TRBP ) |
|---|---|
| Gene Full Name: | nuclear receptor coactivator 6 |
| Band: | 20q11.22 |
| Quick Links | Entrez ID:23054; OMIM: 605299; Uniprot ID:NCOA6_HUMAN; ENSEMBL ID: ENSG00000198646; HGNC ID: 15936 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>NCOA6|23054|nucleotide
ATGGTTTTGGATGACCTTCCAAACTTAGAAGACATCTATACTTCCTTGTGTTCATCAACAATGGAAGACTCAGAGATGGATTTTGACTCTGGACTAGAAGATGAT
GACACAAAAAGTGATAGTATTTTGGAGGATTCCACAATTTTTGTGGCCTTCAAAGGAAATATAGATGATAAAGACTTCAAATGGAAATTAGATGCAATATTGAAA
AACGTGCCCAATTTGTTACACATGGAGTCCAGCAAGCTAAAAGTACAGAAGGTGGAGCCCTGGAACAGCGTGCGTGTGACATTCAACATCCCCCGGGAAGCAGCG
GAGCGGCTACGGATCCTTGCTCAGAGCAACAACCAGCAGCTTCGGGATTTAGGGATTCTCTCCGTTCAGATTGAAGGGGAAGGTGCTATTAACCTGGCTTTGGCT
CAGAACCGAAGCCAAGATGTGAGAATGAATGGACCCATGGGAGCTGGAAATTCAGTTAGGATGGAGGCGGGATTTCCTATGGCAAGTGGTCCAGGAATAATAAGG
ATGAACAACCCTGCCACTGTTATGATACCCCCGGGTGGAAATGTGTCATCTTCCATGATGGCACCAGGCCCCAATCCAGAGCTGCAGCCCAGGACTCCTCGCCCT
GCTTCTCAGTCAGATGCAATGGATCCACTCCTCTCTGGGCTCCATATACAGCAGCAAAGTCATCCCTCAGGATCTTTAGCTCCCCCACATCACCCAATGCAGCCT
GTCTCTGTGAACAGACAAATGAACCCAGCTAATTTTCCCCAGCTGCAGCAGCAGCAGCAACAACAACAACAGCAGCAGCAGCAGCAGCAGCAGCAACAACAGCAA
CAGCAGCAACAACAGTTGCAGGCAAGACCCCCACAGCAACATCAGCAGCAACAGCCACAGGGAATTCGACCCCAGTTTACTGCCCCAACTCAGGTGCCTGTTCCT
CCAGGCTGGAACCAGCTGCCTTCTGGAGCCCTTCAACCTCCTCCAGCCCAGGGTTCTCTGGGCACAATGACTGCAAACCAAGGGTGGAAGAAGGCTCCCTTGCCC
GGCCCAATGCAACAGCAACTCCAGGCAAGACCATCCTTAGCCACGGTACAGACGCCTTCCCACCCTCCCCCTCCATATCCCTTTGGCAGCCAGCAAGCCTCACAA
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ATGGTTTTGGATGACCTTCCAAACTTAGAAGACATCTATACTTCCTTGTGTTCATCAACAATGGAAGACTCAGAGATGGATTTTGACTCTGGACTAGAAGATGAT
GACACAAAAAGTGATAGTATTTTGGAGGATTCCACAATTTTTGTGGCCTTCAAAGGAAATATAGATGATAAAGACTTCAAATGGAAATTAGATGCAATATTGAAA
AACGTGCCCAATTTGTTACACATGGAGTCCAGCAAGCTAAAAGTACAGAAGGTGGAGCCCTGGAACAGCGTGCGTGTGACATTCAACATCCCCCGGGAAGCAGCG
GAGCGGCTACGGATCCTTGCTCAGAGCAACAACCAGCAGCTTCGGGATTTAGGGATTCTCTCCGTTCAGATTGAAGGGGAAGGTGCTATTAACCTGGCTTTGGCT
CAGAACCGAAGCCAAGATGTGAGAATGAATGGACCCATGGGAGCTGGAAATTCAGTTAGGATGGAGGCGGGATTTCCTATGGCAAGTGGTCCAGGAATAATAAGG
ATGAACAACCCTGCCACTGTTATGATACCCCCGGGTGGAAATGTGTCATCTTCCATGATGGCACCAGGCCCCAATCCAGAGCTGCAGCCCAGGACTCCTCGCCCT
GCTTCTCAGTCAGATGCAATGGATCCACTCCTCTCTGGGCTCCATATACAGCAGCAAAGTCATCCCTCAGGATCTTTAGCTCCCCCACATCACCCAATGCAGCCT
GTCTCTGTGAACAGACAAATGAACCCAGCTAATTTTCCCCAGCTGCAGCAGCAGCAGCAACAACAACAACAGCAGCAGCAGCAGCAGCAGCAGCAACAACAGCAA
CAGCAGCAACAACAGTTGCAGGCAAGACCCCCACAGCAACATCAGCAGCAACAGCCACAGGGAATTCGACCCCAGTTTACTGCCCCAACTCAGGTGCCTGTTCCT
CCAGGCTGGAACCAGCTGCCTTCTGGAGCCCTTCAACCTCCTCCAGCCCAGGGTTCTCTGGGCACAATGACTGCAAACCAAGGGTGGAAGAAGGCTCCCTTGCCC
GGCCCAATGCAACAGCAACTCCAGGCAAGACCATCCTTAGCCACGGTACAGACGCCTTCCCACCCTCCCCCTCCATATCCCTTTGGCAGCCAGCAAGCCTCACAA
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>NCOA6|23054|protein
MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKDFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAA
ERLRILAQSNNQQLRDLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRP
ASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVP
PGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ
PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQAN
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MVLDDLPNLEDIYTSLCSSTMEDSEMDFDSGLEDDDTKSDSILEDSTIFVAFKGNIDDKDFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAA
ERLRILAQSNNQQLRDLGILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRP
ASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVP
PGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQ
PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQAN
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (0) | 0 (1) | 1 (1) | 0 (0) | 0 (0) | 0 (1) | 3 (3) | 0 (0) | 0 (0) | 5 (6) |
Syndromic Autism Gene TopGenome-Wide Association Studies(By Ethnic Group) TopCNV Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Sanders, 2011 | Simons Simplex Collection | SNP microarray | - | - | ASD | 1127 | 1127 | - | - | - | - | - |
Linkage Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Allen-Brady, 2008 | - | SNP-based genomic screen |  | | ASD | 1 | - | 1 | - | 7 | 22 | 29 |
Low Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies TopNGS de novo Mutation Studies Top| Reference | Case Number | Family Number | de novo Number | Title |
|---|---|---|---|---|
| Takata A, 2018 | 262 | 262 | 322 | Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Di |
NGS Mosaic SNV Studies Top| Reference | Case Number | Family Number | Mosaic Number | Title |
|---|---|---|---|---|
| Dou Y, 2017 | - | 2361 | 230 | Postzygotic single-nucleotide mosaicisms contribute to the etiology of autism spectrum disorder and |
| Lim ET, 2017 | - | 5947 | 376 | Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder |
| Krupp DR, 2017 | - | 2264 | 247 | Exonic Mosaic Mutations Contribute Risk for Autism Spectrum Disorder |
NGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.