Evidence Details for MORC3
Basic Information Top
| Gene Symbol: | MORC3 ( NXP2,ZCW5,ZCWCC3 ) |
|---|---|
| Gene Full Name: | MORC family CW-type zinc finger 3 |
| Band: | 21q22.12 |
| Quick Links | Entrez ID:23515; OMIM: 610078; Uniprot ID:MORC3_HUMAN; ENSEMBL ID: ENSG00000159256; HGNC ID: 23572 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>MORC3|23515|nucleotide
ATGGCGGCGCAGCCACCCCGCGGGATACGCCTCAGCGCGCTTTGCCCGAAGTTTTTACATACAAATTCTACTAGTCACACCTGGCCATTCAGTGCAGTTGCTGAA
TTAATAGATAATGCTTATGATCCTGATGTGAACGCTAAACAAATATGGATTGACAAAACAGTGATAAATGACCATATATGCTTGACATTCACCGACAATGGGAAT
GGTATGACTTCTGATAAATTACATAAAATGCTAAGCTTTGGCTTCAGTGACAAAGTCACCATGAATGGTCATGTCCCAGTTGGATTATATGGGAATGGCTTCAAG
TCGGGTTCTATGCGTCTGGGTAAAGACGCAATCGTTTTTACCAAAAATGGAGAAAGCATGAGCGTGGGCCTTTTGTCTCAGACCTACTTGGAAGTCATAAAAGCG
GAGCATGTTGTTGTTCCAATAGTGGCATTCAACAAGCACCGACAGATGATTAATTTAGCAGAATCAAAAGCCAGCCTTGCTGCAATTCTGGAACATTCTCTGTTT
TCCACGGAACAGAAGTTACTGGCAGAACTTGATGCTATTATAGGCAAGAAGGGGACGAGGATCATCATTTGGAATCTTAGAAGCTACAAAAATGCAACAGAGTTC
GATTTTGAAAAGGATAAATATGATATCAGAATTCCCGAGGATTTAGATGAGATAACAGGGAAGAAGGGGTACAAGAAGCAGGAAAGGATGGACCAGATTGCCCCT
GAGAGTGACTATTCCCTGAGGGCTTATTGCAGTATATTATATCTAAAGCCAAGAATGCAGATCATCCTACGTGGACAGAAAGTGAAGACACAGCTGGTTTCGAAG
AGTCTTGCCTACATCGAACGTGATGTTTATCGACCAAAATTTTTATCTAAAACAGTGAGAATTACCTTTGGATTCAACTGCAGAAATAAAGATCATTATGGGATA
ATGATGTATCACAGAAATAGACTCATCAAAGCTTATGAAAAAGTTGGATGTCAGTTAAGGGCAAACAACATGGGTGTTGGAGTGGTTGGAATTATAGAGTGTAAT
TTCCTTAAGCCAACTCATAATAAACAAGATTTCGACTATACTAATGAGTACAGACTTACAATAACAGCACTAGGAGAAAAGCTGAATGATTACTGGAATGAAATG
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ATGGCGGCGCAGCCACCCCGCGGGATACGCCTCAGCGCGCTTTGCCCGAAGTTTTTACATACAAATTCTACTAGTCACACCTGGCCATTCAGTGCAGTTGCTGAA
TTAATAGATAATGCTTATGATCCTGATGTGAACGCTAAACAAATATGGATTGACAAAACAGTGATAAATGACCATATATGCTTGACATTCACCGACAATGGGAAT
GGTATGACTTCTGATAAATTACATAAAATGCTAAGCTTTGGCTTCAGTGACAAAGTCACCATGAATGGTCATGTCCCAGTTGGATTATATGGGAATGGCTTCAAG
TCGGGTTCTATGCGTCTGGGTAAAGACGCAATCGTTTTTACCAAAAATGGAGAAAGCATGAGCGTGGGCCTTTTGTCTCAGACCTACTTGGAAGTCATAAAAGCG
GAGCATGTTGTTGTTCCAATAGTGGCATTCAACAAGCACCGACAGATGATTAATTTAGCAGAATCAAAAGCCAGCCTTGCTGCAATTCTGGAACATTCTCTGTTT
TCCACGGAACAGAAGTTACTGGCAGAACTTGATGCTATTATAGGCAAGAAGGGGACGAGGATCATCATTTGGAATCTTAGAAGCTACAAAAATGCAACAGAGTTC
GATTTTGAAAAGGATAAATATGATATCAGAATTCCCGAGGATTTAGATGAGATAACAGGGAAGAAGGGGTACAAGAAGCAGGAAAGGATGGACCAGATTGCCCCT
GAGAGTGACTATTCCCTGAGGGCTTATTGCAGTATATTATATCTAAAGCCAAGAATGCAGATCATCCTACGTGGACAGAAAGTGAAGACACAGCTGGTTTCGAAG
AGTCTTGCCTACATCGAACGTGATGTTTATCGACCAAAATTTTTATCTAAAACAGTGAGAATTACCTTTGGATTCAACTGCAGAAATAAAGATCATTATGGGATA
ATGATGTATCACAGAAATAGACTCATCAAAGCTTATGAAAAAGTTGGATGTCAGTTAAGGGCAAACAACATGGGTGTTGGAGTGGTTGGAATTATAGAGTGTAAT
TTCCTTAAGCCAACTCATAATAAACAAGATTTCGACTATACTAATGAGTACAGACTTACAATAACAGCACTAGGAGAAAAGCTGAATGATTACTGGAATGAAATG
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>MORC3|23515|protein
MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFK
SGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAESKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNATEF
DFEKDKYDIRIPEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGI
MMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWR
KLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLL
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MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFK
SGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAESKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNATEF
DFEKDKYDIRIPEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGI
MMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWR
KLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLL
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1 (1) | 0 (2) | 0 (0) | 0 (0) | 0 (0) | 1 (3) |
Syndromic Autism Gene TopGenome-Wide Association Studies(By Ethnic Group) TopCNV Studies TopLinkage Studies TopLow Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies Top Microarray Studies: 1
| Reference | Source | Tissue | #Subjects (% Women) |
ADI-R | ADOS | Endo- pheno | Diagnosis | Normal Controls (% Women) |
Fold Change | Up/ Down | P/Q value | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baron, 2006_1 | America | human EBV-transformed lymphoblastoid cell lines | 3 (33.33%) |  |  | - | autism | 3 (33.33%) |
1.3 | Up | 0.02 | |
| ||||||||||||
Proteomics Studies:0
| Reference | Source | Tissue | Platform | #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Normal Controls(% Women) | |
|---|---|---|---|---|---|---|---|---|---|
| No Evidence. | |||||||||
NGS de novo Mutation Studies Top| Reference | Case Number | Family Number | de novo Number | Title |
|---|---|---|---|---|
| Dong S, 2014 | 787 | 787 | 42 | De novo insertions and deletions of predominantly paternal origin are associated with autism spectru |
| De Rubeis S, 2014 | 2270 | - | 1702 | Synaptic, transcriptional and chromatin genes disrupted in autism |
NGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.