Evidence Details for ARHGEF26
Basic Information Top
| Gene Symbol: | ARHGEF26 ( CSGEF,DKFZp434D146,HMFN1864,SGEF ) |
|---|---|
| Gene Full Name: | Rho guanine nucleotide exchange factor (GEF) 26 |
| Band: | 3q25.2 |
| Quick Links | Entrez ID:26084; OMIM: NA; Uniprot ID:ARHGQ_HUMAN; ENSEMBL ID: ENSG00000114790; HGNC ID: 24490 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>ARHGEF26|26084|nucleotide
ATGGACGGCGAGAGCGAGGTGGATTTTTCTAGCAACAGCATAACCCCTTTGTGGCGGAGGCGGTCGATTCCTCAGCCCCACCAGGTTCTGGGCCGGAGCAAGCCG
AGGCCCCAGTCCTACCAGAGCCCCAACGGGTTACTAATTACGGATTTCCCGGTGGAGGACGGAGGGACGCTCCTCGCAGCGCAGATTCCCGCCCAGGTGCCCACC
GCCTCGGACAGCAGGACGGTACATAGGAGCCCCCTGCTTCTGGGCGCCCAGCGGAGAGCGGTGGCCAATGGTGGGACGGCATCCCCGGAGTACAGGGCTGCCTCT
CCTCGACTTCGACGGCCCAAGTCACCCAAGCTCCCCAAAGCGGTGCCTGGCGGCTCCCCGAAATCCCCAGCAAATGGCGCGGTGACCTTGCCTGCGCCGCCGCCG
CCGCCGGTTCTGCGCCCCCCGCGGACTCCTAACGCGCCCGCCCCCTGCACCCCCGAGGAGGACCTTACTGGGTTGACTGCCAGCCCGGTGCCTTCGCCCACTGCA
AATGGCCTTGCCGCTAATAACGACTCTCCTGGGTCAGGTTCGCAGTCCGGCCGGAAGGCAAAGGACCCCGAACGGGGGCTCTTTCCTGGGCCCCAGAAAAGTTCT
TCGGAACAAAAACTCCCCCTCCAAAGGCTGCCCTCCCAGGAGAACGAGCTCCTCGAGAATCCTTCCGTGGTTTTGAGTACAAACAGCCCCGCCGCCCTCAAAGTG
GGGAAGCAGCAGATCATTCCGAAGAGTCTGGCCTCGGAAATTAAAATAAGTAAATCCAACAATCAAAATGTGGAGCCCCACAAGAGACTCCTCAAGGTGCGCAGC
ATGGTGGAGGGCCTAGGAGGACCCCTGGGTCACGCAGGGGAGGAGAGTGAGGTCGATAACGACGTGGATAGCCCAGGGTCTCTGCGGAGAGGCTTGCGGTCCACG
TCTTATCGCAGGGCAGTGGTCAGTGGCTTTGATTTTGACAGTCCTACCAGCTCGAAGAAGAAGAACAGAATGTCCCAGCCTGTTCTGAAAGTGGTGATGGAAGAC
AAGGAGAAGTTTTCCAGTCTGGGAAGGATAAAGAAAAAAATGCTGAAAGGACAAGGAACATTTGATGGGGAAGAAAATGCTGTCCTGTATCAAAACTACAAGGAA
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ATGGACGGCGAGAGCGAGGTGGATTTTTCTAGCAACAGCATAACCCCTTTGTGGCGGAGGCGGTCGATTCCTCAGCCCCACCAGGTTCTGGGCCGGAGCAAGCCG
AGGCCCCAGTCCTACCAGAGCCCCAACGGGTTACTAATTACGGATTTCCCGGTGGAGGACGGAGGGACGCTCCTCGCAGCGCAGATTCCCGCCCAGGTGCCCACC
GCCTCGGACAGCAGGACGGTACATAGGAGCCCCCTGCTTCTGGGCGCCCAGCGGAGAGCGGTGGCCAATGGTGGGACGGCATCCCCGGAGTACAGGGCTGCCTCT
CCTCGACTTCGACGGCCCAAGTCACCCAAGCTCCCCAAAGCGGTGCCTGGCGGCTCCCCGAAATCCCCAGCAAATGGCGCGGTGACCTTGCCTGCGCCGCCGCCG
CCGCCGGTTCTGCGCCCCCCGCGGACTCCTAACGCGCCCGCCCCCTGCACCCCCGAGGAGGACCTTACTGGGTTGACTGCCAGCCCGGTGCCTTCGCCCACTGCA
AATGGCCTTGCCGCTAATAACGACTCTCCTGGGTCAGGTTCGCAGTCCGGCCGGAAGGCAAAGGACCCCGAACGGGGGCTCTTTCCTGGGCCCCAGAAAAGTTCT
TCGGAACAAAAACTCCCCCTCCAAAGGCTGCCCTCCCAGGAGAACGAGCTCCTCGAGAATCCTTCCGTGGTTTTGAGTACAAACAGCCCCGCCGCCCTCAAAGTG
GGGAAGCAGCAGATCATTCCGAAGAGTCTGGCCTCGGAAATTAAAATAAGTAAATCCAACAATCAAAATGTGGAGCCCCACAAGAGACTCCTCAAGGTGCGCAGC
ATGGTGGAGGGCCTAGGAGGACCCCTGGGTCACGCAGGGGAGGAGAGTGAGGTCGATAACGACGTGGATAGCCCAGGGTCTCTGCGGAGAGGCTTGCGGTCCACG
TCTTATCGCAGGGCAGTGGTCAGTGGCTTTGATTTTGACAGTCCTACCAGCTCGAAGAAGAAGAACAGAATGTCCCAGCCTGTTCTGAAAGTGGTGATGGAAGAC
AAGGAGAAGTTTTCCAGTCTGGGAAGGATAAAGAAAAAAATGCTGAAAGGACAAGGAACATTTGATGGGGAAGAAAATGCTGTCCTGTATCAAAACTACAAGGAA
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>ARHGEF26|26084|protein
MDGESEVDFSSNSITPLWRRRSIPQPHQVLGRSKPRPQSYQSPNGLLITDFPVEDGGTLLAAQIPAQVPTASDSRTVHRSPLLLGAQRRAVANGGTASPEYRAAS
PRLRRPKSPKLPKAVPGGSPKSPANGAVTLPAPPPPPVLRPPRTPNAPAPCTPEEDLTGLTASPVPSPTANGLAANNDSPGSGSQSGRKAKDPERGLFPGPQKSS
SEQKLPLQRLPSQENELLENPSVVLSTNSPAALKVGKQQIIPKSLASEIKISKSNNQNVEPHKRLLKVRSMVEGLGGPLGHAGEESEVDNDVDSPGSLRRGLRST
SYRRAVVSGFDFDSPTSSKKKNRMSQPVLKVVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQ
LSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTAST
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MDGESEVDFSSNSITPLWRRRSIPQPHQVLGRSKPRPQSYQSPNGLLITDFPVEDGGTLLAAQIPAQVPTASDSRTVHRSPLLLGAQRRAVANGGTASPEYRAAS
PRLRRPKSPKLPKAVPGGSPKSPANGAVTLPAPPPPPVLRPPRTPNAPAPCTPEEDLTGLTASPVPSPTANGLAANNDSPGSGSQSGRKAKDPERGLFPGPQKSS
SEQKLPLQRLPSQENELLENPSVVLSTNSPAALKVGKQQIIPKSLASEIKISKSNNQNVEPHKRLLKVRSMVEGLGGPLGHAGEESEVDNDVDSPGSLRRGLRST
SYRRAVVSGFDFDSPTSSKKKNRMSQPVLKVVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQ
LSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTAST
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 1 (1) | 0 (1) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 4 (2) |
Syndromic Autism Gene TopGenome-Wide Association Studies (By Ethnic Group) Top Family Based Association Studies: 1
| Reference | Stage | Platform | #Families | Affecteds | Result | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ (range) |
||||||
| CAUCASIAN | |||||||||||
| Ma, 2009_1 | Discovery | Illumina's Human 1M v1 Beadchip | 438 | - (-) |  |  | ASD | - - |
- - | ||
Case Control Based Association Studies: 0
| Reference | Stage | Platform | ASD Cases | Normal Controls | Result | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ | #Subjects (% Women) |
Age (range) |
|||||
| No Evidence. | ||||||||||||
CNV Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Pinto, 2010 | - | SNP microarray, qPCR | | | ASD | - | - | - | - | 996 | 1287 | 2283 |
Linkage Studies TopLow Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies TopNGS de novo Mutation Studies TopNGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.