Evidence Details for FBXO24
Basic Information Top
| Gene Symbol: | FBXO24 ( DKFZp434I1122,FBX24 ) |
|---|---|
| Gene Full Name: | F-box protein 24 |
| Band: | 7q22.1 |
| Quick Links | Entrez ID:26261; OMIM: 609097; Uniprot ID:FBX24_HUMAN; ENSEMBL ID: ENSG00000106336; HGNC ID: 13595 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>FBXO24|26261|nucleotide
ATGGTGAAGAGAAGCTGCCCTTCTTGTGGCTCGGAGCTTGGGGTTGAAGAGAAGAGGGGGAAAGGAAATCCGATTTCCATCCAGTTGTTCCCCCCAGAGCTGGTG
GAGCATATCATCTCATTCCTCCCAGTCAGAGACCTTGTTGCCCTCGGCCAGACCTGCCGCTACTTCCACGAAGTGTGCGATGGGGAAGGCGTGTGGAGACGCATC
TGTCGCAGACTCAGTCCGCGCCTCCAAGATCAGGGTTCTGGAGTCCGGCCCTGGAAGAGAGCTGCCATTCTGAACTACACGAAGGGCCTGTATTTCCAGGCATTT
GGAGGCCGCCGCCGATGTCTCAGCAAGAGCGTGGCCCCCTTGCTAGCCCACGGCTACCGCCGCTTCTTGCCCACCAAGGATCACGTCTTCATTCTTGACTACGTG
GGGACCCTCTTCTTCCTCAAAAATGCCCTGGTCTCCACCCTCGGCCAGATGCAGTGGAAGCGGGCCTGTCGCTATGTTGTGTTGTGTCGTGGAGCCAAGGATTTT
GCCTCGGACCCAAGGTGTGACACAGTTTACCGTAAATACCTCTACGTCTTGGCCACTCGGGAGCCGCAGGAAGTGGTGGGTACCACCAGCAGCCGGGCCTGTGAC
TGTGTTGAGGTCTATCTGCAGTCTAGTGGGCAGCGGGTCTTCAAGATGACATTCCACCACTCAATGACCTTCAAGCAGATCGTGCTGGTTGGTCAGGAGACCCAG
CGGGCTCTACTGCTCCTCACAGAGGAAGGAAAGATCTACTCTTTGGTAGTGAATGAGACCCAGCTTGACCAGCCACGCTCCTACACGGTTCAGCTGGCCCTGAGG
AAGGTGTCCCACTACCTGCCTCACCTGCGCGTGGCCTGCATGACTTCCAACCAGAGCAGCACCCTCTACGTCACAGACCAGGGGGGAGTGTATTTTGAGGTGCAT
ACCCCAGGGGTGTATCGCGATCTCTTTGGGACCCTTCAAGCCTTTGACCCCCTGGACCAGCAGATGCCGCTTGCTCTCTCACTGCCTGCCAAGATCCTATTCTGT
GCTCTTGGCTACAACCACCTTGGCCTGGTGGATGAATTTGGCCGAATCTTCATGCAAGGAAATAACAGATACGGGCAGCTAGGAACAGGGGACAAAATGGACCGA
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ATGGTGAAGAGAAGCTGCCCTTCTTGTGGCTCGGAGCTTGGGGTTGAAGAGAAGAGGGGGAAAGGAAATCCGATTTCCATCCAGTTGTTCCCCCCAGAGCTGGTG
GAGCATATCATCTCATTCCTCCCAGTCAGAGACCTTGTTGCCCTCGGCCAGACCTGCCGCTACTTCCACGAAGTGTGCGATGGGGAAGGCGTGTGGAGACGCATC
TGTCGCAGACTCAGTCCGCGCCTCCAAGATCAGGGTTCTGGAGTCCGGCCCTGGAAGAGAGCTGCCATTCTGAACTACACGAAGGGCCTGTATTTCCAGGCATTT
GGAGGCCGCCGCCGATGTCTCAGCAAGAGCGTGGCCCCCTTGCTAGCCCACGGCTACCGCCGCTTCTTGCCCACCAAGGATCACGTCTTCATTCTTGACTACGTG
GGGACCCTCTTCTTCCTCAAAAATGCCCTGGTCTCCACCCTCGGCCAGATGCAGTGGAAGCGGGCCTGTCGCTATGTTGTGTTGTGTCGTGGAGCCAAGGATTTT
GCCTCGGACCCAAGGTGTGACACAGTTTACCGTAAATACCTCTACGTCTTGGCCACTCGGGAGCCGCAGGAAGTGGTGGGTACCACCAGCAGCCGGGCCTGTGAC
TGTGTTGAGGTCTATCTGCAGTCTAGTGGGCAGCGGGTCTTCAAGATGACATTCCACCACTCAATGACCTTCAAGCAGATCGTGCTGGTTGGTCAGGAGACCCAG
CGGGCTCTACTGCTCCTCACAGAGGAAGGAAAGATCTACTCTTTGGTAGTGAATGAGACCCAGCTTGACCAGCCACGCTCCTACACGGTTCAGCTGGCCCTGAGG
AAGGTGTCCCACTACCTGCCTCACCTGCGCGTGGCCTGCATGACTTCCAACCAGAGCAGCACCCTCTACGTCACAGACCAGGGGGGAGTGTATTTTGAGGTGCAT
ACCCCAGGGGTGTATCGCGATCTCTTTGGGACCCTTCAAGCCTTTGACCCCCTGGACCAGCAGATGCCGCTTGCTCTCTCACTGCCTGCCAAGATCCTATTCTGT
GCTCTTGGCTACAACCACCTTGGCCTGGTGGATGAATTTGGCCGAATCTTCATGCAAGGAAATAACAGATACGGGCAGCTAGGAACAGGGGACAAAATGGACCGA
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>FBXO24|26261|protein
MVKRSCPSCGSELGVEEKRGKGNPISIQLFPPELVEHIISFLPVRDLVALGQTCRYFHEVCDGEGVWRRICRRLSPRLQDQGSGVRPWKRAAILNYTKGLYFQAF
GGRRRCLSKSVAPLLAHGYRRFLPTKDHVFILDYVGTLFFLKNALVSTLGQMQWKRACRYVVLCRGAKDFASDPRCDTVYRKYLYVLATREPQEVVGTTSSRACD
CVEVYLQSSGQRVFKMTFHHSMTFKQIVLVGQETQRALLLLTEEGKIYSLVVNETQLDQPRSYTVQLALRKVSHYLPHLRVACMTSNQSSTLYVTDQGGVYFEVH
TPGVYRDLFGTLQAFDPLDQQMPLALSLPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPITLWCGLNHSLVLSQSSEFSKEL
LGCGCGAGGRLPGWPKGSASFVKLQVKVPLCACALCATRECLYILSSHDIEQHAPYRHLPASRVVGTPEPSLGARAPQDPGGMAQACEEYLSQIHSCQTLQDRTE
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MVKRSCPSCGSELGVEEKRGKGNPISIQLFPPELVEHIISFLPVRDLVALGQTCRYFHEVCDGEGVWRRICRRLSPRLQDQGSGVRPWKRAAILNYTKGLYFQAF
GGRRRCLSKSVAPLLAHGYRRFLPTKDHVFILDYVGTLFFLKNALVSTLGQMQWKRACRYVVLCRGAKDFASDPRCDTVYRKYLYVLATREPQEVVGTTSSRACD
CVEVYLQSSGQRVFKMTFHHSMTFKQIVLVGQETQRALLLLTEEGKIYSLVVNETQLDQPRSYTVQLALRKVSHYLPHLRVACMTSNQSSTLYVTDQGGVYFEVH
TPGVYRDLFGTLQAFDPLDQQMPLALSLPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPITLWCGLNHSLVLSQSSEFSKEL
LGCGCGAGGRLPGWPKGSASFVKLQVKVPLCACALCATRECLYILSSHDIEQHAPYRHLPASRVVGTPEPSLGARAPQDPGGMAQACEEYLSQIHSCQTLQDRTE
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 1 (3) | 0 (0) | 1 (1) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 6 (4) |
Syndromic Autism Gene TopGenome-Wide Association Studies (By Ethnic Group) Top Family Based Association Studies: 2
| Reference | Stage | Platform | #Families | Affecteds | Result | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ (range) |
||||||
| CAUCASIAN | |||||||||||
| Maestrini, 2009_2 | Discovery | GoldenGate assay (Illumina, San Diego, CA, USA) | 127 | 127 (-) |  | | ASD | - - |
- - | ||
| Maestrini, 2009_3 | Replication | the Mass Extend iPLEX Gold (Sequenom, San Diego, CA, USA) and TaqMan platforms | 390 | 390 (-) | | | ASD | - - |
- - | ||
Case Control Based Association Studies: 1
| Reference | Stage | Platform | ASD Cases | Normal Controls | Result | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ | #Subjects (% Women) |
Age (range) |
|||||
| CAUCASIAN | ||||||||||||
| Maestrini, 2009_5 | Discovery | GoldenGate assay (Illumina, San Diego, CA, USA) | 127 (20.47%) | | | ASD | - - |
- | 188 (21.28%) |
- - | ||
CNV Studies TopLinkage Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Monaco, 2001 | - | microsatellite-based genomic screen | | | PDD | 152 | - | 152 | - | - | - | - |
Low Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies TopNGS de novo Mutation Studies TopNGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.