Evidence Details for RGL4
Basic Information Top
| Gene Symbol: | RGL4 ( MGC119678,MGC119680,Rgr ) |
|---|---|
| Gene Full Name: | ral guanine nucleotide dissociation stimulator-like 4 |
| Band: | 22q11.23 |
| Quick Links | Entrez ID:266747; OMIM: 612214; Uniprot ID:RGDSR_HUMAN; ENSEMBL ID: ENSG00000159496; HGNC ID: 31911 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>RGL4|266747|nucleotide
ATGAGGAAGCTGCTCACAAATCTGCCTGCAGCTGCAGTCTTGAGTGCCCAGGTGTACAGTGCTGTGCTCCAGGGCCTTTGGGAAGAGAATGTCTGTGGGACGCCA
GGGCGCACGAGGGTCTGTACAGCCCTGCTGTATGGCCAGGTCTGCCCCTTCCAGGACAGCACTGATGGCTTACGCACCATCACCTCCATTTTGTTCAACTGGCCC
CCCGAAAACACTTCAGTTTACTATCAGCCCCCGCAACGGTCATCTTTCCGGATAAAGCTGGCCTTCAGGAACCTCTCCTGGCCTGGACTGGGCTTGGAGGACCAT
CAGGAAATTGTCCTAGGCCAGTTGGTGCTTCCGGAGCCCAACGAGGCCAAGCCAGATGATCCTGCTCCACGTCCTGGGCAACACGCATTAACAATGCCGGCCCTG
GAGCCAGCACCACCACTGCTGGCGGACCTGGGGCCTGCTCTGGAGCCAGAGTCACCTGCAGCCCTGGGTCCACCAGGATATCTACATTCAGCACCAGGGCCAGCA
CCAGCACCAGGGGAAGGGCCCCCTCCAGGGACAGTGCTGGAGCCACAGTCAGCCCCAGAGTCCTCCTGTCCCTGTCGTGGGTCTGTAAAGAACCAACCCAGTGAG
GAGCTGCCTGACATGACGACCTTCCCTCCCAGGCTGCTGGCAGAGCAGCTGACCCTCATGGATGCGGAGCTGTTCAAGAAGGTGGTGCTCCACGAATGCTTGGGC
TGCATCTGGGGCCAAGGACATCTGAAGGGGAATGAGCACATGGCACCCACAGTTCGTGCCACCATCGCACACTTCAACAGGCTCACCAACTGCATCACCACCTCC
TGCCTCGGGGACCACAGCATGAGGGCCCGGGACAGGGCCAGGGTGGTGGAGCACTGGATCAAGGTGGCCAGGGAGTGCCTAAGCCTCAACAACTTCTCCTCGGTG
CACGTCATCGTCTCTGCTCTGTGCAGCAACCCAATAGGTCAGCTACACAAGACGTGGGCAGGAGTGTCCAGCAAAAGCATGAAAGAGCTAAAAGAACTCTGCAAA
AAAGACACTGCAGTGAAGAGGGACCTACTGATCAAGGCGGGGAGCTTTAAGGTGGCCACCCAGGAGAGGAACCCCCAGAGAGTCCAGATGAGGCTGCGGAGGCAG
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ATGAGGAAGCTGCTCACAAATCTGCCTGCAGCTGCAGTCTTGAGTGCCCAGGTGTACAGTGCTGTGCTCCAGGGCCTTTGGGAAGAGAATGTCTGTGGGACGCCA
GGGCGCACGAGGGTCTGTACAGCCCTGCTGTATGGCCAGGTCTGCCCCTTCCAGGACAGCACTGATGGCTTACGCACCATCACCTCCATTTTGTTCAACTGGCCC
CCCGAAAACACTTCAGTTTACTATCAGCCCCCGCAACGGTCATCTTTCCGGATAAAGCTGGCCTTCAGGAACCTCTCCTGGCCTGGACTGGGCTTGGAGGACCAT
CAGGAAATTGTCCTAGGCCAGTTGGTGCTTCCGGAGCCCAACGAGGCCAAGCCAGATGATCCTGCTCCACGTCCTGGGCAACACGCATTAACAATGCCGGCCCTG
GAGCCAGCACCACCACTGCTGGCGGACCTGGGGCCTGCTCTGGAGCCAGAGTCACCTGCAGCCCTGGGTCCACCAGGATATCTACATTCAGCACCAGGGCCAGCA
CCAGCACCAGGGGAAGGGCCCCCTCCAGGGACAGTGCTGGAGCCACAGTCAGCCCCAGAGTCCTCCTGTCCCTGTCGTGGGTCTGTAAAGAACCAACCCAGTGAG
GAGCTGCCTGACATGACGACCTTCCCTCCCAGGCTGCTGGCAGAGCAGCTGACCCTCATGGATGCGGAGCTGTTCAAGAAGGTGGTGCTCCACGAATGCTTGGGC
TGCATCTGGGGCCAAGGACATCTGAAGGGGAATGAGCACATGGCACCCACAGTTCGTGCCACCATCGCACACTTCAACAGGCTCACCAACTGCATCACCACCTCC
TGCCTCGGGGACCACAGCATGAGGGCCCGGGACAGGGCCAGGGTGGTGGAGCACTGGATCAAGGTGGCCAGGGAGTGCCTAAGCCTCAACAACTTCTCCTCGGTG
CACGTCATCGTCTCTGCTCTGTGCAGCAACCCAATAGGTCAGCTACACAAGACGTGGGCAGGAGTGTCCAGCAAAAGCATGAAAGAGCTAAAAGAACTCTGCAAA
AAAGACACTGCAGTGAAGAGGGACCTACTGATCAAGGCGGGGAGCTTTAAGGTGGCCACCCAGGAGAGGAACCCCCAGAGAGTCCAGATGAGGCTGCGGAGGCAG
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>RGL4|266747|protein
MRKLLTNLPAAAVLSAQVYSAVLQGLWEENVCGTPGRTRVCTALLYGQVCPFQDSTDGLRTITSILFNWPPENTSVYYQPPQRSSFRIKLAFRNLSWPGLGLEDH
QEIVLGQLVLPEPNEAKPDDPAPRPGQHALTMPALEPAPPLLADLGPALEPESPAALGPPGYLHSAPGPAPAPGEGPPPGTVLEPQSAPESSCPCRGSVKNQPSE
ELPDMTTFPPRLLAEQLTLMDAELFKKVVLHECLGCIWGQGHLKGNEHMAPTVRATIAHFNRLTNCITTSCLGDHSMRARDRARVVEHWIKVARECLSLNNFSSV
HVIVSALCSNPIGQLHKTWAGVSSKSMKELKELCKKDTAVKRDLLIKAGSFKVATQERNPQRVQMRLRRQKKGVVPFLGDFLTELQRLDSAIPDDLDGNTNKRSK
EVRVLQEMQLLQVAAMNYRLRPLEKFVTYFTRMEQLSDKESYKLSCQLEPENP
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MRKLLTNLPAAAVLSAQVYSAVLQGLWEENVCGTPGRTRVCTALLYGQVCPFQDSTDGLRTITSILFNWPPENTSVYYQPPQRSSFRIKLAFRNLSWPGLGLEDH
QEIVLGQLVLPEPNEAKPDDPAPRPGQHALTMPALEPAPPLLADLGPALEPESPAALGPPGYLHSAPGPAPAPGEGPPPGTVLEPQSAPESSCPCRGSVKNQPSE
ELPDMTTFPPRLLAEQLTLMDAELFKKVVLHECLGCIWGQGHLKGNEHMAPTVRATIAHFNRLTNCITTSCLGDHSMRARDRARVVEHWIKVARECLSLNNFSSV
HVIVSALCSNPIGQLHKTWAGVSSKSMKELKELCKKDTAVKRDLLIKAGSFKVATQERNPQRVQMRLRRQKKGVVPFLGDFLTELQRLDSAIPDDLDGNTNKRSK
EVRVLQEMQLLQVAAMNYRLRPLEKFVTYFTRMEQLSDKESYKLSCQLEPENP
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (0) | 1 (6) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 2 (6) |
Syndromic Autism Gene TopGenome-Wide Association Studies(By Ethnic Group) TopCNV Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Roubertie, 2001 | - | FISH |  | | autism | - | - | - | - | 1 | - | 1 |
| Niklasson, 2002 | Sweden | FISH | | | autism | - | - | - | - | 1 | - | 1 |
| Ramelli, 2008 | - | FISH | | | ASD | - | - | - | - | 1 | - | 1 |
| Pinto, 2010 | - | SNP microarray, qPCR |  | | ASD | - | - | - | - | 996 | 1287 | 2283 |
| Levy, 2011 | Simons Simplex Collection | aCGH | - | - | ASD | 915 | 915 | - | - | - | - | - |
| Sanders, 2011 | Simons Simplex Collection | SNP microarray | - | - | ASD | 1127 | 1127 | - | - | - | - | - |
Linkage Studies TopLow Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies TopNGS de novo Mutation Studies TopNGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.