Evidence Details for PGP
Basic Information Top
| Gene Symbol: | PGP ( MGC4692 ) |
|---|---|
| Gene Full Name: | phosphoglycolate phosphatase |
| Band: | 16p13.3 |
| Quick Links | Entrez ID:283871; OMIM: 172280; Uniprot ID:PGP_HUMAN; ENSEMBL ID: ENSG00000184207; HGNC ID: 8909 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>PGP|283871|nucleotide
ATGGCGGCGGCGGAGGCCGGTGGCGACGACGCCCGCTGCGTGCGGCTGAGCGCCGAGCGGGCACAGGCGCTGCTGGCCGACGTGGACACGCTGCTGTTCGACTGC
GACGGCGTGCTGTGGCGCGGGGAGACCGCCGTGCCTGGCGCGCCCGAGGCCCTGCGGGCGCTGCGAGCCCGCGGCAAGCGCCTGGGCTTCATCACCAACAACAGC
AGCAAGACCCGCGCTGCCTACGCCGAGAAGCTGCGGCGCCTGGGCTTCGGCGGCCCCGCGGGGCCCGGCGCCAGCCTGGAGGTCTTCGGCACGGCCTACTGCACC
GCGCTCTACCTGCGCCAGCGCCTGGCCGGCGCCCCCGCGCCCAAGGCCTACGTGCTGGGCAGCCCAGCCCTGGCCGCGGAGCTGGAGGCCGTGGGCGTCGCCAGC
GTGGGCGTGGGGCCCGAGCCACTGCAGGGCGAGGGTCCCGGCGACTGGCTGCACGCGCCGCTGGAGCCCGACGTGCGCGCGGTGGTGGTGGGCTTTGACCCGCAC
TTCAGCTACATGAAGCTCACCAAGGCCCTGCGCTACCTGCAGCAGCCCGGCTGCCTGCTCGTGGGCACCAACATGGACAACCGGCTTCCGCTTGAGAACGGCCGC
TTCATCGCGGGTACCGGGTGTCTGGTCCGAGCCGTGGAGATGGCCGCCCAGCGCCAGGCCGACATCATCGGGAAGCCCAGCCGCTTCATTTTCGACTGCGTGTCC
CAGGAATACGGCATCAACCCCGAGCGCACCGTCATGGTGGGAGACCGCCTGGACACAGACATCCTCCTAGGCGCCACCTGTGGCCTGAAGACCATCCTGACCCTC
ACCGGAGTCTCCACTCTAGGGGATGTGAAGAATAATCAGGAAAGTGACTGCGTGTCTAAGAAGAAAATGGTCCCTGACTTCTATGTTGACAGCATAGCCGACCTT
TTGCCTGCCCTTCAAGGTTAA
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ATGGCGGCGGCGGAGGCCGGTGGCGACGACGCCCGCTGCGTGCGGCTGAGCGCCGAGCGGGCACAGGCGCTGCTGGCCGACGTGGACACGCTGCTGTTCGACTGC
GACGGCGTGCTGTGGCGCGGGGAGACCGCCGTGCCTGGCGCGCCCGAGGCCCTGCGGGCGCTGCGAGCCCGCGGCAAGCGCCTGGGCTTCATCACCAACAACAGC
AGCAAGACCCGCGCTGCCTACGCCGAGAAGCTGCGGCGCCTGGGCTTCGGCGGCCCCGCGGGGCCCGGCGCCAGCCTGGAGGTCTTCGGCACGGCCTACTGCACC
GCGCTCTACCTGCGCCAGCGCCTGGCCGGCGCCCCCGCGCCCAAGGCCTACGTGCTGGGCAGCCCAGCCCTGGCCGCGGAGCTGGAGGCCGTGGGCGTCGCCAGC
GTGGGCGTGGGGCCCGAGCCACTGCAGGGCGAGGGTCCCGGCGACTGGCTGCACGCGCCGCTGGAGCCCGACGTGCGCGCGGTGGTGGTGGGCTTTGACCCGCAC
TTCAGCTACATGAAGCTCACCAAGGCCCTGCGCTACCTGCAGCAGCCCGGCTGCCTGCTCGTGGGCACCAACATGGACAACCGGCTTCCGCTTGAGAACGGCCGC
TTCATCGCGGGTACCGGGTGTCTGGTCCGAGCCGTGGAGATGGCCGCCCAGCGCCAGGCCGACATCATCGGGAAGCCCAGCCGCTTCATTTTCGACTGCGTGTCC
CAGGAATACGGCATCAACCCCGAGCGCACCGTCATGGTGGGAGACCGCCTGGACACAGACATCCTCCTAGGCGCCACCTGTGGCCTGAAGACCATCCTGACCCTC
ACCGGAGTCTCCACTCTAGGGGATGTGAAGAATAATCAGGAAAGTGACTGCGTGTCTAAGAAGAAAATGGTCCCTGACTTCTATGTTGACAGCATAGCCGACCTT
TTGCCTGCCCTTCAAGGTTAA
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>PGP|283871|protein
MAAAEAGGDDARCVRLSAERAQALLADVDTLLFDCDGVLWRGETAVPGAPEALRALRARGKRLGFITNNSSKTRAAYAEKLRRLGFGGPAGPGASLEVFGTAYCT
ALYLRQRLAGAPAPKAYVLGSPALAAELEAVGVASVGVGPEPLQGEGPGDWLHAPLEPDVRAVVVGFDPHFSYMKLTKALRYLQQPGCLLVGTNMDNRLPLENGR
FIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPERTVMVGDRLDTDILLGATCGLKTILTLTGVSTLGDVKNNQESDCVSKKKMVPDFYVDSIADL
LPALQG
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MAAAEAGGDDARCVRLSAERAQALLADVDTLLFDCDGVLWRGETAVPGAPEALRALRARGKRLGFITNNSSKTRAAYAEKLRRLGFGGPAGPGASLEVFGTAYCT
ALYLRQRLAGAPAPKAYVLGSPALAAELEAVGVASVGVGPEPLQGEGPGDWLHAPLEPDVRAVVVGFDPHFSYMKLTKALRYLQQPGCLLVGTNMDNRLPLENGR
FIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPERTVMVGDRLDTDILLGATCGLKTILTLTGVSTLGDVKNNQESDCVSKKKMVPDFYVDSIADL
LPALQG
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (0) | 1 (1) | 1 (2) | 0 (0) | 1 (1) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 5 (4) |
Syndromic Autism Gene TopGenome-Wide Association Studies(By Ethnic Group) TopCNV Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Gazzellone MJ, 2014 | China | - |  | | - | - | - | - | - | 104 | 2108 | 2212 |
Linkage Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Buxbaum, 2004 | USA | microsatellite-based genomic screen |  | | autism | 115 | - | 115 | - | - | - | - |
| Lauritsen, 2006 | Faroe Islands | microsatellite-based genomic screen | | | autism | - | - | - | - | 12 | 44 | 56 |
Low Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies Top Microarray Studies: 1
| Reference | Source | Tissue | #Subjects (% Women) |
ADI-R | ADOS | Endo- pheno | Diagnosis | Normal Controls (% Women) |
Fold Change | Up/ Down | P/Q value | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Voineagu, 2011_1 | Unknown | 16 frontal cortex(BA9) and 13 temporal cortex(BA41 | 16 (25.00%) | | | - | autism | 16 (6.25%) |
0.871049 | Down | 3.61006 | |
| ||||||||||||
Proteomics Studies:0
| Reference | Source | Tissue | Platform | #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Normal Controls(% Women) | |
|---|---|---|---|---|---|---|---|---|---|
| No Evidence. | |||||||||
NGS de novo Mutation Studies TopNGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.