Evidence Details for APOBEC4
Basic Information Top
| Gene Symbol: | APOBEC4 ( C1orf169,MGC26594 ) |
|---|---|
| Gene Full Name: | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) |
| Band: | 1q25.3 |
| Quick Links | Entrez ID:403314; OMIM: 609908; Uniprot ID:ABEC4_HUMAN; ENSEMBL ID: ENSG00000173627; HGNC ID: 32152 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>APOBEC4|403314|nucleotide
ATGGAGCCCATATATGAGGAGTACCTAGCAAATCATGGAACAATAGTAAAACCATATTACTGGCTAAGCTTCTCTCTCGATTGCTCTAATTGTCCTTACCATATT
CGAACAGGTGAAGAAGCAAGAGTTTCCCTCACAGAATTTTGTCAGATTTTTGGATTCCCTTATGGGACAACATTTCCTCAAACAAAACACCTCACATTTTATGAA
CTAAAAACTTCTTCTGGTAGCCTGGTGCAAAAGGGCCATGCTAGCAGTTGCACTGGGAATTATATCCATCCAGAATCAATGCTCTTTGAAATGAATGGTTATCTT
GACTCAGCCATATACAATAATGACAGCATCAGGCATATCATTCTGTATTCCAACAACTCCCCTTGTAATGAAGCTAACCACTGCTGCATCAGCAAAATGTATAAT
TTCCTGATTACGTATCCAGGCATCACTCTTAGTATTTATTTTTCTCAGCTCTATCATACTGAGATGGACTTTCCTGCCTCAGCATGGAACCGCGAAGCTCTCCGG
AGCCTGGCCAGCTTATGGCCGCGGGTTGTTTTGAGTCCAATAAGTGGTGGGATCTGGCATTCTGTTCTCCACAGCTTTATAAGTGGTGTCTCAGGATCACATGTT
TTTCAGCCCATTTTAACTGGGAGAGCACTGGCTGACAGGCACAACGCATATGAAATCAATGCCATAACAGGCGTAAAACCTTACTTCACTGATGTTCTTCTCCAG
ACAAAAAGGAATCCAAACACAAAAGCTCAGGAGGCTTTAGAGAGCTACCCCTTAAACAATGCCTTTCCTGGACAGTTTTTTCAAATGCCGAGTGGACAACTCCAA
CCCAACCTACCTCCAGACCTCAGGGCTCCTGTTGTTTTTGTGCTAGTGCCTCTCAGGGACTTACCACCAATGCATATGGGCCAAAACCCAAATAAACCCAGGAAT
ATCGTAAGGCACTTAAATATGCCTCAAATGTCATTCCAGGAAACCAAGGACCTTGGAAGGCTTCCCACTGGAAGGTCAGTGGAGATAGTGGAAATCACAGAACAG
TTTGCAAGTAGCAAGGAGGCAGATGAAAAGAAGAAGAAGAAAGGGAAGAAATAA
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ATGGAGCCCATATATGAGGAGTACCTAGCAAATCATGGAACAATAGTAAAACCATATTACTGGCTAAGCTTCTCTCTCGATTGCTCTAATTGTCCTTACCATATT
CGAACAGGTGAAGAAGCAAGAGTTTCCCTCACAGAATTTTGTCAGATTTTTGGATTCCCTTATGGGACAACATTTCCTCAAACAAAACACCTCACATTTTATGAA
CTAAAAACTTCTTCTGGTAGCCTGGTGCAAAAGGGCCATGCTAGCAGTTGCACTGGGAATTATATCCATCCAGAATCAATGCTCTTTGAAATGAATGGTTATCTT
GACTCAGCCATATACAATAATGACAGCATCAGGCATATCATTCTGTATTCCAACAACTCCCCTTGTAATGAAGCTAACCACTGCTGCATCAGCAAAATGTATAAT
TTCCTGATTACGTATCCAGGCATCACTCTTAGTATTTATTTTTCTCAGCTCTATCATACTGAGATGGACTTTCCTGCCTCAGCATGGAACCGCGAAGCTCTCCGG
AGCCTGGCCAGCTTATGGCCGCGGGTTGTTTTGAGTCCAATAAGTGGTGGGATCTGGCATTCTGTTCTCCACAGCTTTATAAGTGGTGTCTCAGGATCACATGTT
TTTCAGCCCATTTTAACTGGGAGAGCACTGGCTGACAGGCACAACGCATATGAAATCAATGCCATAACAGGCGTAAAACCTTACTTCACTGATGTTCTTCTCCAG
ACAAAAAGGAATCCAAACACAAAAGCTCAGGAGGCTTTAGAGAGCTACCCCTTAAACAATGCCTTTCCTGGACAGTTTTTTCAAATGCCGAGTGGACAACTCCAA
CCCAACCTACCTCCAGACCTCAGGGCTCCTGTTGTTTTTGTGCTAGTGCCTCTCAGGGACTTACCACCAATGCATATGGGCCAAAACCCAAATAAACCCAGGAAT
ATCGTAAGGCACTTAAATATGCCTCAAATGTCATTCCAGGAAACCAAGGACCTTGGAAGGCTTCCCACTGGAAGGTCAGTGGAGATAGTGGAAATCACAGAACAG
TTTGCAAGTAGCAAGGAGGCAGATGAAAAGAAGAAGAAGAAAGGGAAGAAATAA
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>APOBEC4|403314|protein
MEPIYEEYLANHGTIVKPYYWLSFSLDCSNCPYHIRTGEEARVSLTEFCQIFGFPYGTTFPQTKHLTFYELKTSSGSLVQKGHASSCTGNYIHPESMLFEMNGYL
DSAIYNNDSIRHIILYSNNSPCNEANHCCISKMYNFLITYPGITLSIYFSQLYHTEMDFPASAWNREALRSLASLWPRVVLSPISGGIWHSVLHSFISGVSGSHV
FQPILTGRALADRHNAYEINAITGVKPYFTDVLLQTKRNPNTKAQEALESYPLNNAFPGQFFQMPSGQLQPNLPPDLRAPVVFVLVPLRDLPPMHMGQNPNKPRN
IVRHLNMPQMSFQETKDLGRLPTGRSVEIVEITEQFASSKEADEKKKKKGKK
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MEPIYEEYLANHGTIVKPYYWLSFSLDCSNCPYHIRTGEEARVSLTEFCQIFGFPYGTTFPQTKHLTFYELKTSSGSLVQKGHASSCTGNYIHPESMLFEMNGYL
DSAIYNNDSIRHIILYSNNSPCNEANHCCISKMYNFLITYPGITLSIYFSQLYHTEMDFPASAWNREALRSLASLWPRVVLSPISGGIWHSVLHSFISGVSGSHV
FQPILTGRALADRHNAYEINAITGVKPYFTDVLLQTKRNPNTKAQEALESYPLNNAFPGQFFQMPSGQLQPNLPPDLRAPVVFVLVPLRDLPPMHMGQNPNKPRN
IVRHLNMPQMSFQETKDLGRLPTGRSVEIVEITEQFASSKEADEKKKKKGKK
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (2) | 1 (3) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 2 (5) |
Syndromic Autism Gene TopGenome-Wide Association Studies (By Ethnic Group) Top Family Based Association Studies: 2
| Reference | Stage | Platform | #Families | Affecteds | Result | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ (range) |
||||||
| CAUCASIAN | |||||||||||
| Salyakina, 2010_2 | Replication | Illumina HumanHap 550K BeadChip | 110 | - (-) |  |  | AS | - (3-21) |
- >70 | ||
| Salyakina, 2010_1 | Discovery | Illumina HumanHap 550K BeadChip | 124 | - (-) | | | AS | - (3-21) |
- >70 | ||
Case Control Based Association Studies: 0
| Reference | Stage | Platform | ASD Cases | Normal Controls | Result | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ | #Subjects (% Women) |
Age (range) |
|||||
| No Evidence. | ||||||||||||
CNV Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Bremer, 2011 | - | aCGH | | | ASD | - | - | - | - | 223 | - | 223 |
| Levy, 2011 | Simons Simplex Collection | aCGH | - | - | ASD | 915 | 915 | - | - | - | - | - |
| Brand H, 2015 | - | CMA;WGS | - | - | ASD | - | - | - | - | 259 | - | 259 |
Linkage Studies TopLow Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies TopNGS de novo Mutation Studies TopNGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.