Evidence Details for TPPP3
Basic Information Top
| Gene Symbol: | TPPP3 ( p20,p25gamma ) |
|---|---|
| Gene Full Name: | tubulin polymerization-promoting protein family member 3 |
| Band: | 16q22.1 |
| Quick Links | Entrez ID:51673; OMIM: NA; Uniprot ID:TPPP3_HUMAN; ENSEMBL ID: ENSG00000159713; HGNC ID: 24162 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>TPPP3|51673|nucleotide
ATGGCAGCGAGCACAGACATGGCTGGGCTGGAGGAGAGCTTCCGCAAGTTTGCCATCCATGGTGACCCCAAGGCCAGTGGGCAAGAGATGAATGGCAAGAACTGG
GCCAAGCTGTGCAAGGACTGCAAGGTGGCTGACGGAAAGTCCGTGACAGGGACCGATGTGGACATCGTCTTCTCCAAAGTCAAGGGGAAGTCTGCTCGGGTCATC
AACTATGAGGAGTTCAAGAAGGCCCTGGAAGAGCTGGCGACCAAGAGATTCAAGGGGAAGAGCAAGGAGGAGGCCTTCGATGCCATCTGCCAGCTGGTGGCAGGC
AAAGAGCCAGCCAATGTGGGCGTCACTAAAGCAAAAACAGGGGGTGCTGTAGACCGGCTGACGGACACCAGCAGATACACGGGCTCCCACAAGGAGCGCTTCGAT
GAGAGCGGCAAGGGCAAGGGCATTGCGGGACGGCAGGACATCCTGGACGACAGTGGCTACGTGAGCGCCTACAAGAATGCAGGCACCTACGATGCCAAGGTGAAG
AAGTGA
Show »
ATGGCAGCGAGCACAGACATGGCTGGGCTGGAGGAGAGCTTCCGCAAGTTTGCCATCCATGGTGACCCCAAGGCCAGTGGGCAAGAGATGAATGGCAAGAACTGG
GCCAAGCTGTGCAAGGACTGCAAGGTGGCTGACGGAAAGTCCGTGACAGGGACCGATGTGGACATCGTCTTCTCCAAAGTCAAGGGGAAGTCTGCTCGGGTCATC
AACTATGAGGAGTTCAAGAAGGCCCTGGAAGAGCTGGCGACCAAGAGATTCAAGGGGAAGAGCAAGGAGGAGGCCTTCGATGCCATCTGCCAGCTGGTGGCAGGC
AAAGAGCCAGCCAATGTGGGCGTCACTAAAGCAAAAACAGGGGGTGCTGTAGACCGGCTGACGGACACCAGCAGATACACGGGCTCCCACAAGGAGCGCTTCGAT
GAGAGCGGCAAGGGCAAGGGCATTGCGGGACGGCAGGACATCCTGGACGACAGTGGCTACGTGAGCGCCTACAAGAATGCAGGCACCTACGATGCCAAGGTGAAG
AAGTGA
Show »
>TPPP3|51673|protein
MAASTDMAGLEESFRKFAIHGDPKASGQEMNGKNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKSARVINYEEFKKALEELATKRFKGKSKEEAFDAICQLVAG
KEPANVGVTKAKTGGAVDRLTDTSRYTGSHKERFDESGKGKGIAGRQDILDDSGYVSAYKNAGTYDAKVKK
Show »
MAASTDMAGLEESFRKFAIHGDPKASGQEMNGKNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKSARVINYEEFKKALEELATKRFKGKSKEEAFDAICQLVAG
KEPANVGVTKAKTGGAVDRLTDTSRYTGSHKERFDESGKGKGIAGRQDILDDSGYVSAYKNAGTYDAKVKK
Show »
Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (0) | 1 (2) | 0 (0) | 0 (0) | 1 (1) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 3 (3) |
Syndromic Autism Gene TopGenome-Wide Association Studies(By Ethnic Group) TopCNV Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Wassink, 2001 | USA | Chromosomal analysis of G-band |  | | autism | - | - | - | - | 278 | - | 278 |
| Bucan, 2009 | USA | SNP microarray |  | | autism, ASD | 912 | - | 912 | - | - | 1488 | 1488 |
Linkage Studies TopLow Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies Top Microarray Studies: 1
| Reference | Source | Tissue | #Subjects (% Women) |
ADI-R | ADOS | Endo- pheno | Diagnosis | Normal Controls (% Women) |
Fold Change | Up/ Down | P/Q value | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Voineagu, 2011_1 | Unknown | 16 frontal cortex(BA9) and 13 temporal cortex(BA41 | 16 (25.00%) | | | - | autism | 16 (6.25%) |
1.03404 | Up | 59.058 | |
| ||||||||||||
Proteomics Studies:0
| Reference | Source | Tissue | Platform | #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Normal Controls(% Women) | |
|---|---|---|---|---|---|---|---|---|---|
| No Evidence. | |||||||||
NGS de novo Mutation Studies TopNGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.