Evidence Details for SEPT5
Basic Information Top
| Gene Symbol: | SEPT5 ( CDCREL,CDCREL-1,CDCREL1,H5,PNUTL1 ) |
|---|---|
| Gene Full Name: | septin 5 |
| Band: | 22q11.21 |
| Quick Links | Entrez ID:5413; OMIM: 602724; Uniprot ID:SEPT5_HUMAN; ENSEMBL ID: ENSG00000184702; HGNC ID: 9164 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>SEPT5|5413|nucleotide
ATGGACTCGCTGGCAGCGCCCCAGGACCGCCTGGTGGAGCAGCTGCTGTCGCCGCGGACCCAGGCCCAGAGGCGGCTCAAGGACATTGACAAGCAGTACGTGGGC
TTCGCCACACTGCCCAACCAGGTGCACCGCAAGTCGGTGAAGAAAGGCTTTGACTTCACACTCATGGTGGCTGGTGAGTCAGGCCTGGGGAAGTCCACACTGGTC
CACAGCCTCTTCCTGACAGACTTGTACAAGGACCGGAAGCTGCTCAGTGCTGAGGAGCGCATCAGCCAGACGGTAGAGATTCTAAAACACACGGTGGACATTGAG
GAGAAGGGAGTCAAGCTGAAGCTCACCATCGTGGACACGCCGGGATTCGGGGACGCTGTCAACAACACCGAGTGCTGGAAGCCCATCACCGACTATGTGGACCAG
CAGTTTGAGCAGTACTTCCGTGATGAGAGCGGCCTCAACCGAAAGAACATCCAAGACAACCGAGTGCACTGCTGCCTATACTTCATCTCCCCCTTCGGGCATGGG
CTGCGGCCAGTGGATGTGGGTTTCATGAAGGCATTGCATGAGAAGGTCAACATCGTGCCTCTCATCGCCAAAGCTGACTGTCTTGTCCCCAGTGAGATCCGGAAG
CTGAAGGAGCGGATCCGGGAGGAGATTGACAAGTTTGGGATCCATGTATACCAGTTCCCTGAGTGTGACTCGGACGAGGATGAGGACTTCAAGCAGCAGGACCGG
GAACTGAAGGAGAGCGCGCCCTTCGCCGTTATAGGCAGCAACACGGTGGTGGAGGCCAAGGGGCAGCGGGTCCGGGGCCGACTGTACCCCTGGGGGATCGTGGAG
GGCGCATTGCGACTTCGTGAAGCTGCGCAACATGCTCATCCGCACGCATATGCACGACCTCAAGGACGTGACGTGCGACGTGCACTACGAGAACTACCGCGCGCA
CTGCATCCAGCAGATGACCAGCAAACTGACCCAGGACAGCCGCATGGAGAGCCCCATCCCGATCCTGCCGCTGCCCACCCCGGACGCCGAGACTGA
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ATGGACTCGCTGGCAGCGCCCCAGGACCGCCTGGTGGAGCAGCTGCTGTCGCCGCGGACCCAGGCCCAGAGGCGGCTCAAGGACATTGACAAGCAGTACGTGGGC
TTCGCCACACTGCCCAACCAGGTGCACCGCAAGTCGGTGAAGAAAGGCTTTGACTTCACACTCATGGTGGCTGGTGAGTCAGGCCTGGGGAAGTCCACACTGGTC
CACAGCCTCTTCCTGACAGACTTGTACAAGGACCGGAAGCTGCTCAGTGCTGAGGAGCGCATCAGCCAGACGGTAGAGATTCTAAAACACACGGTGGACATTGAG
GAGAAGGGAGTCAAGCTGAAGCTCACCATCGTGGACACGCCGGGATTCGGGGACGCTGTCAACAACACCGAGTGCTGGAAGCCCATCACCGACTATGTGGACCAG
CAGTTTGAGCAGTACTTCCGTGATGAGAGCGGCCTCAACCGAAAGAACATCCAAGACAACCGAGTGCACTGCTGCCTATACTTCATCTCCCCCTTCGGGCATGGG
CTGCGGCCAGTGGATGTGGGTTTCATGAAGGCATTGCATGAGAAGGTCAACATCGTGCCTCTCATCGCCAAAGCTGACTGTCTTGTCCCCAGTGAGATCCGGAAG
CTGAAGGAGCGGATCCGGGAGGAGATTGACAAGTTTGGGATCCATGTATACCAGTTCCCTGAGTGTGACTCGGACGAGGATGAGGACTTCAAGCAGCAGGACCGG
GAACTGAAGGAGAGCGCGCCCTTCGCCGTTATAGGCAGCAACACGGTGGTGGAGGCCAAGGGGCAGCGGGTCCGGGGCCGACTGTACCCCTGGGGGATCGTGGAG
GGCGCATTGCGACTTCGTGAAGCTGCGCAACATGCTCATCCGCACGCATATGCACGACCTCAAGGACGTGACGTGCGACGTGCACTACGAGAACTACCGCGCGCA
CTGCATCCAGCAGATGACCAGCAAACTGACCCAGGACAGCCGCATGGAGAGCCCCATCCCGATCCTGCCGCTGCCCACCCCGGACGCCGAGACTGA
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>SEPT5|5413|protein
MDSLAAPQDRLVEQLLSPRTQAQRRLKDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIE
EKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRK
LKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEGALRLREAAQHAHPHAYARPQGRDVRRALRELPRA
LHPADDQQTDPGQPHGEPHPDPAAAHPGRRD
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MDSLAAPQDRLVEQLLSPRTQAQRRLKDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIE
EKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRK
LKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEGALRLREAAQHAHPHAYARPQGRDVRRALRELPRA
LHPADDQQTDPGQPHGEPHPDPAAAHPGRRD
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (0) | 1 (10) | 1 (1) | 0 (0) | 0 (0) | 0 (1) | 0 (0) | 0 (0) | 0 (0) | 4 (12) |
Syndromic Autism Gene TopGenome-Wide Association Studies(By Ethnic Group) TopCNV Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Roubertie, 2001 | - | FISH |  | | autism | - | - | - | - | 1 | - | 1 |
| Niklasson, 2002 | Sweden | FISH | | | autism | - | - | - | - | 1 | - | 1 |
| Szatmari, 2007 | Europe, North America | SNP microarray |  | | ASD | 1491 | - | - | - | - | - | 0 |
| Ramelli, 2008 | - | FISH | | | ASD | - | - | - | - | 1 | - | 1 |
| Marshall, 2008 | - | SNP microarray | | | ASD | 427 | 238 | 189 | - | 427 | 500 | 927 |
| Christian, 2008 | USA | aCGH | | | ASD | 397 | 35 | 362 | - | 397 | 372 | 769 |
| Pinto, 2010 | - | SNP microarray, qPCR | | | ASD | - | - | - | - | 996 | 1287 | 2283 |
| Bremer, 2011 | - | aCGH | | | ASD | - | - | - | - | 223 | - | 223 |
| Levy, 2011 | Simons Simplex Collection | aCGH | - | - | ASD | 915 | 915 | - | - | - | - | - |
| Sanders, 2011 | Simons Simplex Collection | SNP microarray | - | - | ASD | 1127 | 1127 | - | - | - | - | - |
Linkage Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Bailey, 1998 | - | microsatellite-based genomic screen | | | PDD | 99 | - | 99 | - | - | - | - |
Low Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies TopNGS de novo Mutation Studies Top| Reference | Case Number | Family Number | de novo Number | Title |
|---|---|---|---|---|
| Yuen RK, 2016 | 200 | - | 301 | Genome-wide characteristics of de novo mutations in autism. |
NGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.