Evidence Details for FEZF2
Basic Information Top
| Gene Symbol: | FEZF2 ( FEZ,FEZL,FLJ10142,TOF,ZFP312,ZNF312 ) |
|---|---|
| Gene Full Name: | FEZ family zinc finger 2 |
| Band: | 3p14.2 |
| Quick Links | Entrez ID:55079; OMIM: 607414; Uniprot ID:FEZF2_HUMAN; ENSEMBL ID: ENSG00000153266; HGNC ID: 13506 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>FEZF2|55079|nucleotide
ATGGCAAGCTCGGCTTCCCTGGAGACCATGGTGCCCCCGGCCTGCCCGCGCGCCGGAGCGTCGCCGGCCACTTCCAAGACACTGGCCTTTTCCATCGAGCGCATC
ATGGCCAAGACGTCGGAGCCCCGTGCGCCCTTTGAGCCCCGGCCTGGAGCGCTAGAGGCGGACGGCAGCCAGGGCAAGAAACTGCTCAACCTCTGCTCGCCGCTG
CCCTGTATGATCCCCCTCCAGCCCCTAGGCTACGAGGTGCCGTCAAAGACACTGCTCAGTTACTCGGAGCTCTGGAAAAGCAGCCTCCGGGCGGGCGGCGGCGGA
GGCGGCGGCGGCGGTGGCGGCGGCGGCGGCGGGGGGGCCCCAGTGTGCGGCGCCAGCGGCTTGTGCAAAACCAACTGTGGCGTGTGCTGCAAGGCCGAGCTGGGC
CTGGCGCCGTCCGCGCTGCCCGCGGGCAGGGTCATCAAGCCGCAGGTCATCAACCAGGCTGTGGGGCTGCCGGCCAGCGGCTCGCTCTACTACTTCAACTACCTG
GACTCGACCGCGTACCCGCCGTCTGAGCTCCTCAGCGGCCACCTCTTCCCGTCTGGCCTCCTCAATGCGCAGGCCCCCGCCGCCCTGGCTGCTCACCCCAAGCTC
TTTCTGCTGGAGAACGCCAAGCTGGCCGGCCTGGCTGCGGACAAGTTCCCCCACCCGGCTCCCTATCCCCATAAGGAGCGCTTGCCGGCGCCGCTGGAGCAGGTA
CTGAAGGAAAACTCGGCCCTGACTGCCGAGCGCGGAGGCGTCAAGGGCCACAGCAAGCTGCCAGGAGGCTCCGCAGATGGCAAGCCCAAAAACTTCACCTGCGAG
GTGTGCGGCAAGGTGTTTAACGCTCACTATAATCTCACCCGCCACATGCCGGTCCACACCGGAGCCAGACCGTTCGTGTGCAAAGTCTGCGGCAAAGGCTTTCGC
CAGGCCAGCACGCTCTGCAGGCACAAAATTATCCACACCCAGGAAAAGCCACATAAATGCAACCAGTGCGGCAAAGCGTTCAACCGCAGCTCCACGCTCAACACG
CATATCCGCATCCACGCGGGCTACAAGCCCTTCGTCTGCGAATTTTGCGGCAAAGGCTTTCACCAAAAAGGGAACTACAAGAACCACAAGCTGACCCACAGCGGC
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ATGGCAAGCTCGGCTTCCCTGGAGACCATGGTGCCCCCGGCCTGCCCGCGCGCCGGAGCGTCGCCGGCCACTTCCAAGACACTGGCCTTTTCCATCGAGCGCATC
ATGGCCAAGACGTCGGAGCCCCGTGCGCCCTTTGAGCCCCGGCCTGGAGCGCTAGAGGCGGACGGCAGCCAGGGCAAGAAACTGCTCAACCTCTGCTCGCCGCTG
CCCTGTATGATCCCCCTCCAGCCCCTAGGCTACGAGGTGCCGTCAAAGACACTGCTCAGTTACTCGGAGCTCTGGAAAAGCAGCCTCCGGGCGGGCGGCGGCGGA
GGCGGCGGCGGCGGTGGCGGCGGCGGCGGCGGGGGGGCCCCAGTGTGCGGCGCCAGCGGCTTGTGCAAAACCAACTGTGGCGTGTGCTGCAAGGCCGAGCTGGGC
CTGGCGCCGTCCGCGCTGCCCGCGGGCAGGGTCATCAAGCCGCAGGTCATCAACCAGGCTGTGGGGCTGCCGGCCAGCGGCTCGCTCTACTACTTCAACTACCTG
GACTCGACCGCGTACCCGCCGTCTGAGCTCCTCAGCGGCCACCTCTTCCCGTCTGGCCTCCTCAATGCGCAGGCCCCCGCCGCCCTGGCTGCTCACCCCAAGCTC
TTTCTGCTGGAGAACGCCAAGCTGGCCGGCCTGGCTGCGGACAAGTTCCCCCACCCGGCTCCCTATCCCCATAAGGAGCGCTTGCCGGCGCCGCTGGAGCAGGTA
CTGAAGGAAAACTCGGCCCTGACTGCCGAGCGCGGAGGCGTCAAGGGCCACAGCAAGCTGCCAGGAGGCTCCGCAGATGGCAAGCCCAAAAACTTCACCTGCGAG
GTGTGCGGCAAGGTGTTTAACGCTCACTATAATCTCACCCGCCACATGCCGGTCCACACCGGAGCCAGACCGTTCGTGTGCAAAGTCTGCGGCAAAGGCTTTCGC
CAGGCCAGCACGCTCTGCAGGCACAAAATTATCCACACCCAGGAAAAGCCACATAAATGCAACCAGTGCGGCAAAGCGTTCAACCGCAGCTCCACGCTCAACACG
CATATCCGCATCCACGCGGGCTACAAGCCCTTCGTCTGCGAATTTTGCGGCAAAGGCTTTCACCAAAAAGGGAACTACAAGAACCACAAGCTGACCCACAGCGGC
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>FEZF2|55079|protein
MASSASLETMVPPACPRAGASPATSKTLAFSIERIMAKTSEPRAPFEPRPGALEADGSQGKKLLNLCSPLPCMIPLQPLGYEVPSKTLLSYSELWKSSLRAGGGG
GGGGGGGGGGGGAPVCGASGLCKTNCGVCCKAELGLAPSALPAGRVIKPQVINQAVGLPASGSLYYFNYLDSTAYPPSELLSGHLFPSGLLNAQAPAALAAHPKL
FLLENAKLAGLAADKFPHPAPYPHKERLPAPLEQVLKENSALTAERGGVKGHSKLPGGSADGKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFR
QASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCTICNKAFHQVYNLTFHMHTHNDKKPFTCA
TCGKGFCRNFDLKKHVRKLHDSVGPAAPSAKDLTRTVQS
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MASSASLETMVPPACPRAGASPATSKTLAFSIERIMAKTSEPRAPFEPRPGALEADGSQGKKLLNLCSPLPCMIPLQPLGYEVPSKTLLSYSELWKSSLRAGGGG
GGGGGGGGGGGGAPVCGASGLCKTNCGVCCKAELGLAPSALPAGRVIKPQVINQAVGLPASGSLYYFNYLDSTAYPPSELLSGHLFPSGLLNAQAPAALAAHPKL
FLLENAKLAGLAADKFPHPAPYPHKERLPAPLEQVLKENSALTAERGGVKGHSKLPGGSADGKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFR
QASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKCTICNKAFHQVYNLTFHMHTHNDKKPFTCA
TCGKGFCRNFDLKKHVRKLHDSVGPAAPSAKDLTRTVQS
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 2 (2) | 1 (1) | 0 (0) | 0 (0) | 1 (1) | 0 (1) | 0 (0) | 0 (0) | 0 (0) | 11 (5) |
Syndromic Autism Gene TopGenome-Wide Association Studies (By Ethnic Group) Top Family Based Association Studies: 1
| Reference | Stage | Platform | #Families | Affecteds | Result | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ (range) |
||||||
| CAUCASIAN | |||||||||||
| Wang, 2009_1 | Discovery | Illumina HumanHap550 BeadChip | 780 | 1299 (-) |  | | ASD | - - |
- - | ||
Case Control Based Association Studies: 1
| Reference | Stage | Platform | ASD Cases | Normal Controls | Result | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ | #Subjects (% Women) |
Age (range) |
|||||
| CAUCASIAN | ||||||||||||
| Wang, 2009_2 | Discovery | Illumina HumanHap550 BeadChip | 1204 (-) | | | ASD | 10.3±6.6 - |
10.9±6.7 | 6491 (-) |
8.8±5.4 - | ||
CNV Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Okumura A, 2014 | - | aCGH | - | - | autistic | 1 | - | - | - | 2 | - | 2 |
Linkage Studies TopLow Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies Top Microarray Studies: 1
| Reference | Source | Tissue | #Subjects (% Women) |
ADI-R | ADOS | Endo- pheno | Diagnosis | Normal Controls (% Women) |
Fold Change | Up/ Down | P/Q value | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Voineagu, 2011_1 | Unknown | 16 frontal cortex(BA9) and 13 temporal cortex(BA41 | 16 (25.00%) | | | - | autism | 16 (6.25%) |
0.975232 | Down | 61.3875 | |
| ||||||||||||
Proteomics Studies:0
| Reference | Source | Tissue | Platform | #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Normal Controls(% Women) | |
|---|---|---|---|---|---|---|---|---|---|
| No Evidence. | |||||||||
NGS de novo Mutation Studies Top| Reference | Case Number | Family Number | de novo Number | Title |
|---|---|---|---|---|
| Sanders SJ, 2012 | - | 238 | 172 | De novo mutations revealed by whole-exome sequencing are strongly associated with autism. |
NGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.