Evidence Details for RGMA
Basic Information Top
| Gene Symbol: | RGMA ( RGM ) |
|---|---|
| Gene Full Name: | RGM domain family, member A |
| Band: | 15q26.1 |
| Quick Links | Entrez ID:56963; OMIM: 607362; Uniprot ID:RGMA_HUMAN; ENSEMBL ID: ENSG00000182175; HGNC ID: 30308 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>RGMA|56963|nucleotide
ATGGGTGGCCTGGGGCCACGACGGGCGGGAACCTCGAGGGAGAGGCTAGTGGTAACAGGCCGAGCTGGATGGATGGGTATGGGGAGAGGGGCAGGACGTTCAGCC
CTGGGATTCTGGCCGACCCTCGCCTTCCTTCTCTGCAGCTTCCCCGCAGCCACCTCCCCGTGCAAGATCCTCAAGTGCAACTCTGAGTTCTGGAGCGCCACGTCG
GGCAGCCACGCCCCAGCCTCAGACGACACCCCCGAGTTCTGTGCAGCCTTGCGCAGCTACGCCCTGTGCACGCGGCGGACGGCCCGCACCTGCCGGGGTGACCTG
GCCTACCACTCGGCCGTCCATGGCATAGAGGACCTCATGAGCCAGCACAACTGCTCCAAGGATGGCCCCACCTCGCAGCCACGCCTGCGCACGCTCCCACCGGCC
GGAGACAGCCAGGAGCGCTCGGACAGCCCCGAGATCTGCCATTACGAGAAGAGCTTTCACAAGCACTCGGCCACCCCCAACTACACGCACTGTGGCCTCTTCGGG
GACCCACACCTCAGGACTTTCACCGACCGCTTCCAGACCTGCAAGGTGCAGGGCGCCTGGCCGCTCATCGACAATAATTACCTGAACGTGCAGGTCACCAACACG
CCTGTGCTGCCCGGCTCAGCGGCCACTGCCACCAGCAAGCTCACCATCATCTTCAAGAACTTCCAGGAGTGTGTGGACCAGAAGGTGTACCAGGCTGAGATGGAC
GAGCTCCCGGCCGCCTTCGTGGATGGCTCTAAGAACGGTGGGGACAAGCACGGGGCCAACAGCCTGAAGATCACTGAGAAGGTGTCAGGCCAGCACGTGGAGATC
CAGGCCAAGTACATCGGCACCACCATCGTGGTGCGCCAGGTGGGCCGCTACCTGACCTTTGCCGTCCGCATGCCAGAGGAAGTGGTCAATGCTGTGGAGGACTGG
GACAGCCAGGGTCTCTACCTCTGCCTGCGGGGCTGCCCCCTCAACCAGCAGATCGACTTCCAGGCCTTCCACACCAATGCTGAGGGCACCGGTGCCCGCAGGCTG
GCAGCCGCCAGCCCTGCACCCACAGCCCCCGAGACCTTCCCATACGAGACAGCCGTGGCCAAGTGCAAGGAGAAGCTGCCGGTGGAGGACCTGTACTACCAGGCC
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ATGGGTGGCCTGGGGCCACGACGGGCGGGAACCTCGAGGGAGAGGCTAGTGGTAACAGGCCGAGCTGGATGGATGGGTATGGGGAGAGGGGCAGGACGTTCAGCC
CTGGGATTCTGGCCGACCCTCGCCTTCCTTCTCTGCAGCTTCCCCGCAGCCACCTCCCCGTGCAAGATCCTCAAGTGCAACTCTGAGTTCTGGAGCGCCACGTCG
GGCAGCCACGCCCCAGCCTCAGACGACACCCCCGAGTTCTGTGCAGCCTTGCGCAGCTACGCCCTGTGCACGCGGCGGACGGCCCGCACCTGCCGGGGTGACCTG
GCCTACCACTCGGCCGTCCATGGCATAGAGGACCTCATGAGCCAGCACAACTGCTCCAAGGATGGCCCCACCTCGCAGCCACGCCTGCGCACGCTCCCACCGGCC
GGAGACAGCCAGGAGCGCTCGGACAGCCCCGAGATCTGCCATTACGAGAAGAGCTTTCACAAGCACTCGGCCACCCCCAACTACACGCACTGTGGCCTCTTCGGG
GACCCACACCTCAGGACTTTCACCGACCGCTTCCAGACCTGCAAGGTGCAGGGCGCCTGGCCGCTCATCGACAATAATTACCTGAACGTGCAGGTCACCAACACG
CCTGTGCTGCCCGGCTCAGCGGCCACTGCCACCAGCAAGCTCACCATCATCTTCAAGAACTTCCAGGAGTGTGTGGACCAGAAGGTGTACCAGGCTGAGATGGAC
GAGCTCCCGGCCGCCTTCGTGGATGGCTCTAAGAACGGTGGGGACAAGCACGGGGCCAACAGCCTGAAGATCACTGAGAAGGTGTCAGGCCAGCACGTGGAGATC
CAGGCCAAGTACATCGGCACCACCATCGTGGTGCGCCAGGTGGGCCGCTACCTGACCTTTGCCGTCCGCATGCCAGAGGAAGTGGTCAATGCTGTGGAGGACTGG
GACAGCCAGGGTCTCTACCTCTGCCTGCGGGGCTGCCCCCTCAACCAGCAGATCGACTTCCAGGCCTTCCACACCAATGCTGAGGGCACCGGTGCCCGCAGGCTG
GCAGCCGCCAGCCCTGCACCCACAGCCCCCGAGACCTTCCCATACGAGACAGCCGTGGCCAAGTGCAAGGAGAAGCTGCCGGTGGAGGACCTGTACTACCAGGCC
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>RGMA|56963|protein
MGGLGPRRAGTSRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDL
AYHSAVHGIEDLMSQHNCSKDGPTSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQTCKVQGAWPLIDNNYLNVQVTNT
PVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDW
DSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLH
LYERTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
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MGGLGPRRAGTSRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDL
AYHSAVHGIEDLMSQHNCSKDGPTSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQTCKVQGAWPLIDNNYLNVQVTNT
PVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDW
DSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLH
LYERTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (1) | 1 (2) | 1 (1) | 0 (0) | 0 (0) | 0 (1) | 0 (0) | 0 (0) | 0 (0) | 4 (5) |
Syndromic Autism Gene TopGenome-Wide Association Studies (By Ethnic Group) Top Family Based Association Studies: 1
| Reference | Stage | Platform | #Families | Affecteds | Result | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ (range) |
||||||
| CAUCASIAN | |||||||||||
| Hussman, 2011_1 | Discovery | Illumina Infinium Human 1 M beadship | 597 | - (-) |  |  | ASD | - - |
- - | ||
Case Control Based Association Studies: 0
| Reference | Stage | Platform | ASD Cases | Normal Controls | Result | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ | #Subjects (% Women) |
Age (range) |
|||||
| No Evidence. | ||||||||||||
CNV Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Bonati, 2005 | - | FISH | | | autism | - | - | - | - | 1 | - | 1 |
| Szatmari, 2007 | Europe, North America | SNP microarray | | | ASD | 1491 | - | - | - | - | - | 0 |
Linkage Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Risch, 1999 | USA | microsatellite-based genomic screen | | | PDD | 90 | - | 90 | - | - | - | - |
Low Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies TopNGS de novo Mutation Studies Top| Reference | Case Number | Family Number | de novo Number | Title |
|---|---|---|---|---|
| O'Roak BJ, 2012 | 1703 | 209 | 242 | Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations. |
NGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.