AutismKB 2.0

Evidence Details for NLGN2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NLGN2 ( KIAA1366 )
Gene Full Name: neuroligin 2
Band: 17p13.1
Quick LinksEntrez ID:57555; OMIM: 606479; Uniprot ID:NLGN2_HUMAN; ENSEMBL ID: ENSG00000169992; HGNC ID: 14290
Relate to Another Database: SFARIGene; denovo-db
Sequences Top
>NLGN2|57555|nucleotide
ATGTGGCTCCTGGCGCTGTGTCTGGTGGGGCTGGCGGGGGCTCAACGCGGGGGAGGGGGTCCCGGCGGCGGCGCCCCGGGCGGCCCCGGCCTGGGCCTCGGCAGC
CTCGGCGAGGAGCGCTTCCCGGTGGTGAACACGGCCTACGGGCGAGTGCGCGGTGTGCGGCGCGAGCTCAACAACGAGATCCTGGGCCCCGTCGTGCAGTTCTTG
GGCGTGCCCTACGCCACGCCGCCCCTGGGCGCCCGCCGCTTCCAGCCGCCTGAGGCGCCCGCCTCGTGGCCCGGCGTGCGCAACGCCACCACCCTGCCGCCCGCC
TGCCCGCAGAACCTGCACGGGGCGCTGCCCGCCATCATGCTGCCTGTGTGGTTCACCGACAACTTGGAGGCGGCCGCCACCTACGTGCAGAACCAGAGCGAGGAC
TGCCTGTACCTCAACCTCTACGTGCCCACCGAGGACGGTCCGCTCACAAAAAAACGTGACGAGGCGACGCTCAATCCGCCAGACACAGATATCCGTGACCCTGGG
AAGAAGCCTGTGATGCTGTTTCTCCATGGCGGCTCCTACATGGAGGGGACCGGAAACATGTTCGATGGCTCAGTCCTGGCTGCCTATGGCAACGTCATTGTAGCC
ACGCTCAACTACCGTCTTGGGGTGCTCGGTTTTCTCAGCACCGGGGACCAGGCTGCAAAAGGCAACTATGGGCTCCTGGACCAGATCCAGGCCCTGCGCTGGCTC
AGTGAAAACATCGCCCACTTTGGGGGCGACCCCGAGCGTATCACCATCTTTGGTTCCGGGGCAGGGGCCTCCTGCGTCAACCTTCTGATCCTCTCCCACCATTCA
GAAGGGCTGTTCCAGAAGGCCATCGCCCAGAGTGGCACCGCCATTTCCAGCTGGTCTGTCAACTACCAGCCGCTCAAGTACACGCGGCTGCTGGCAGCCAAGGTG
GGCTGTGACCGAGAGGACAGCGCTGAAGCTGTGGAGTGTCTGCGCCGGAAGCCCTCCCGGGAGCTGGTGGACCAGGACGTGCAGCCTGCCCGCTACCACATCGCC
TTTGGGCCCGTGGTGGATGGCGACGTGGTCCCCGATGACCCTGAGATCCTCATGCAGCAGGGAGAATTCCTCAACTACGACATGCTCATCGGCGTCAACCAGGGA
Show »

>NLGN2|57555|protein
MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPA
CPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVA
TLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKV
GCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGY
PEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSK
Show »

Evidence summary Top

Click the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
Evidences Syndromic Gene GWAS CNV Linkage Association Expression NGS de novo NGS Mosaic NGS Other Low-Scale Gene Studies Total
Score (No. of Studies) No 0 (0) 0 (3) 1 (1) 0 (0) 0 (0) 2 (2) 0 (0) 0 (0) 0 (0) 22 (6)
Syndromic Autism Gene Top
Genome-Wide Association Studies(By Ethnic Group) Top
CNV Studies Top
Reference Source Method ADI-R ADOS Diagnosis Family Individual
Total Simplex Multiplex Control Affected Control Total
Bremer, 2011 - aCGHASD - - - - 223 - 223
Levy, 2011 Simons Simplex Collection aCGH--ASD 915 915 - - - - -
Sanders, 2011 Simons Simplex Collection SNP microarray--ASD 1127 1127 - - - - -
Linkage Studies Top