Evidence Details for THBS4
Basic Information Top
| Gene Symbol: | THBS4 ( TSP4 ) |
|---|---|
| Gene Full Name: | thrombospondin 4 |
| Band: | 5q14.1 |
| Quick Links | Entrez ID:7060; OMIM: 600715; Uniprot ID:TSP4_HUMAN; ENSEMBL ID: ENSG00000113296; HGNC ID: 11788 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>THBS4|7060|nucleotide
ATGCTGGCCCCGCGCGGAGCCGCCGTCCTCCTGCTGCACCTGGTCCTGCAGCGGTGGCTAGCGGCAGGCGCCCAGGCCACCCCCCAGGTCTTTGACCTTCTCCCA
TCTTCCAGTCAGAGGCTAAACCCAGGCGCTCTGCTGCCAGTCCTGACAGACCCCGCCCTGAATGATCTCTATGTGATTTCCACCTTCAAGCTGCAGACTAAAAGT
TCAGCCACCATCTTCGGTCTTTACTCTTCAACTGACAACAGTAAATATTTTGAATTTACTGTGATGGGACGCTTAAACAAAGCCATCCTCCGTTACCTGAAGAAC
GATGGGAAGGTGCATTTGGTGGTTTTCAACAACCTGCAGCTGGCAGACGGAAGGCGGCACAGGATCCTCCTGAGGCTGAGCAATTTGCAGCGAGGGGCCGGCTCC
CTAGAGCTCTACCTGGACTGCATCCAGGTGGATTCCGTTCACAATCTCCCCAGGGCCTTTGCTGGCCCCTCCCAGAAACCTGAGACCATTGAATTGAGGACTTTC
CAGAGGAAGCCACAGGACTTCTTGGAAGAGCTGAAGCTGGTGGTGAGAGGCTCACTGTTCCAGGTGGCCAGCCTGCAAGACTGCTTCCTGCAGCAGAGTGAGCCA
CTGGCTGCCACAGGCACAGGGGACTTTAACCGGCAGTTCTTGGGTCAAATGACACAATTAAACCAACTCCTGGGAGAGGTGAAGGACCTTCTGAGACAGCAGGTT
AAGGAAACATCATTTTTGCGAAACACCATAGCTGAATGCCAGGCTTGCGGTCCTCTCAAGTTTCAGTCTCCGACCCCAAGCACGGTGGTGCCCCCGGCTCCCCCT
GCACCGCCAACACGCCCACCTCGTCGGTGTGACTCCAACCCATGTTTCCGAGGTGTCCAATGTACCGACAGTAGAGATGGCTTCCAGTGTGGGCCCTGCCCCGAG
GGCTACACAGGAAACGGGATCACCTGTATTGATGTTGATGAGTGCAAATACCATCCCTGCTACCCGGGCGTGCACTGCATAAATTTGTCTCCTGGCTTCAGATGT
GACGCCTGCCCAGTGGGCTTCACAGGGCCCATGGTGCAGGGTGTTGGGATCAGTTTTGCCAAGTCAAACAAGCAGGTCTGCACTGACATTGATGAGTGTCGAAAT
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ATGCTGGCCCCGCGCGGAGCCGCCGTCCTCCTGCTGCACCTGGTCCTGCAGCGGTGGCTAGCGGCAGGCGCCCAGGCCACCCCCCAGGTCTTTGACCTTCTCCCA
TCTTCCAGTCAGAGGCTAAACCCAGGCGCTCTGCTGCCAGTCCTGACAGACCCCGCCCTGAATGATCTCTATGTGATTTCCACCTTCAAGCTGCAGACTAAAAGT
TCAGCCACCATCTTCGGTCTTTACTCTTCAACTGACAACAGTAAATATTTTGAATTTACTGTGATGGGACGCTTAAACAAAGCCATCCTCCGTTACCTGAAGAAC
GATGGGAAGGTGCATTTGGTGGTTTTCAACAACCTGCAGCTGGCAGACGGAAGGCGGCACAGGATCCTCCTGAGGCTGAGCAATTTGCAGCGAGGGGCCGGCTCC
CTAGAGCTCTACCTGGACTGCATCCAGGTGGATTCCGTTCACAATCTCCCCAGGGCCTTTGCTGGCCCCTCCCAGAAACCTGAGACCATTGAATTGAGGACTTTC
CAGAGGAAGCCACAGGACTTCTTGGAAGAGCTGAAGCTGGTGGTGAGAGGCTCACTGTTCCAGGTGGCCAGCCTGCAAGACTGCTTCCTGCAGCAGAGTGAGCCA
CTGGCTGCCACAGGCACAGGGGACTTTAACCGGCAGTTCTTGGGTCAAATGACACAATTAAACCAACTCCTGGGAGAGGTGAAGGACCTTCTGAGACAGCAGGTT
AAGGAAACATCATTTTTGCGAAACACCATAGCTGAATGCCAGGCTTGCGGTCCTCTCAAGTTTCAGTCTCCGACCCCAAGCACGGTGGTGCCCCCGGCTCCCCCT
GCACCGCCAACACGCCCACCTCGTCGGTGTGACTCCAACCCATGTTTCCGAGGTGTCCAATGTACCGACAGTAGAGATGGCTTCCAGTGTGGGCCCTGCCCCGAG
GGCTACACAGGAAACGGGATCACCTGTATTGATGTTGATGAGTGCAAATACCATCCCTGCTACCCGGGCGTGCACTGCATAAATTTGTCTCCTGGCTTCAGATGT
GACGCCTGCCCAGTGGGCTTCACAGGGCCCATGGTGCAGGGTGTTGGGATCAGTTTTGCCAAGTCAAACAAGCAGGTCTGCACTGACATTGATGAGTGTCGAAAT
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>THBS4|7060|protein
MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYVISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKN
DGKVHLVVFNNLQLADGRRHRILLRLSNLQRGAGSLELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEP
LAATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPE
GYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA
ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVL
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MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYVISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKN
DGKVHLVVFNNLQLADGRRHRILLRLSNLQRGAGSLELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEP
LAATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPE
GYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA
ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVL
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (2) | 0 (0) | 1 (1) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 2 (3) |
Syndromic Autism Gene TopGenome-Wide Association Studies (By Ethnic Group) Top Family Based Association Studies: 2
| Reference | Stage | Platform | #Families | Affecteds | Result | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ (range) |
||||||
| CAUCASIAN | |||||||||||
| Salyakina, 2010_1 | Discovery | Illumina HumanHap 550K BeadChip | 124 | - (-) |  |  | AS | - (3-21) |
- >70 | ||
| Salyakina, 2010_2 | Replication | Illumina HumanHap 550K BeadChip | 110 | - (-) | | | AS | - (3-21) |
- >70 | ||
Case Control Based Association Studies: 0
| Reference | Stage | Platform | ASD Cases | Normal Controls | Result | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ | #Subjects (% Women) |
Age (range) |
|||||
| No Evidence. | ||||||||||||
CNV Studies TopLinkage Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Lauritsen, 2006 | Faroe Islands | microsatellite-based genomic screen | | | autism | - | - | - | - | 12 | 44 | 56 |
Low Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies TopNGS de novo Mutation Studies TopNGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.