Evidence Details for RASSF4
Basic Information Top
| Gene Symbol: | RASSF4 ( AD037,MGC44914 ) |
|---|---|
| Gene Full Name: | Ras association (RalGDS/AF-6) domain family member 4 |
| Band: | 10q11.21 |
| Quick Links | Entrez ID:83937; OMIM: 610559; Uniprot ID:RASF4_HUMAN; ENSEMBL ID: ENSG00000107551; HGNC ID: 20793 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>RASSF4|83937|nucleotide
ATGAAGGAAGACTGTCTGCCGAGTTCTCACGTGCCCATCAGTGACAGCAAGTCCATTCAGAAGTCGGAGCTCTTAGGCCTGCTGAAAACCTACAACTGCTACCAT
GAGGGCAAGAGCTTCCAGCTGAGACACCGTGAGGAAGAAGGGACTCTGATCATCGAGGGGCTCCTCAACATTGCCTGGGGGCTGAGGCGGCCCATCCGGCTGCAG
ATGCAGGATGACCGGGAGCAGGTGCACCTCCCCTCCACCTCATGGATGCCCAGACGGCCTAGCTGCCCTCTAAAGGAGCCATCGCCCCAGAACGGGAACATCACA
GCCCAGGGGCCAAGCATTCAGCCAGTGCACAAGGCTGAGAGTTCCACAGACAGCTCGGGGCCCCTGGAGGAGGCAGAGGAGGCCCCCCAGCTGATGCGGACCAAG
AGCGACGCCAGTTGCATGAGCCAGAGGAGGCCCAAGTGCCGCGCCCCCGGTGAGGCCCAGCGCATCCGGCGACACCGGTTCTCTATCAACGGCCACTTCTACAAT
CATAAGACCTCCGTGTTTACTCCAGCCTATGGATCCGTGACCAATGTGAGGGTCAACAGCACCATGACAACCCTGCAGGTGCTCACCCTGCTGCTGAACAAATTT
AGGGTGGAAGATGGCCCCAGTGAGTTCGCACTCTACATCGTTCACGAGTCTGGGGAGCGGACAAAATTAAAAGACTGCGAGTACCCGCTGATTTCCAGAATCCTG
CATGGGCCATGTGAGAAGATCGCCAGGATCTTCCTGATGGAAGCTGACTTGGGCGTGGAAGTCCCCCATGAAGTCGCTCAGTACATTAAGTTTGAAATGCCGGTG
CTGGACAGTTTTGTTGAAAAATTAAAAGAAGAGGAAGAAAGAGAAATAATCAAACTGACCATGAAGTTCCAAGCCCTGCGTCTGACGATGCTGCAGCGCCTGGAG
CAGCTGGTGGAGGCCAAGTAA
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ATGAAGGAAGACTGTCTGCCGAGTTCTCACGTGCCCATCAGTGACAGCAAGTCCATTCAGAAGTCGGAGCTCTTAGGCCTGCTGAAAACCTACAACTGCTACCAT
GAGGGCAAGAGCTTCCAGCTGAGACACCGTGAGGAAGAAGGGACTCTGATCATCGAGGGGCTCCTCAACATTGCCTGGGGGCTGAGGCGGCCCATCCGGCTGCAG
ATGCAGGATGACCGGGAGCAGGTGCACCTCCCCTCCACCTCATGGATGCCCAGACGGCCTAGCTGCCCTCTAAAGGAGCCATCGCCCCAGAACGGGAACATCACA
GCCCAGGGGCCAAGCATTCAGCCAGTGCACAAGGCTGAGAGTTCCACAGACAGCTCGGGGCCCCTGGAGGAGGCAGAGGAGGCCCCCCAGCTGATGCGGACCAAG
AGCGACGCCAGTTGCATGAGCCAGAGGAGGCCCAAGTGCCGCGCCCCCGGTGAGGCCCAGCGCATCCGGCGACACCGGTTCTCTATCAACGGCCACTTCTACAAT
CATAAGACCTCCGTGTTTACTCCAGCCTATGGATCCGTGACCAATGTGAGGGTCAACAGCACCATGACAACCCTGCAGGTGCTCACCCTGCTGCTGAACAAATTT
AGGGTGGAAGATGGCCCCAGTGAGTTCGCACTCTACATCGTTCACGAGTCTGGGGAGCGGACAAAATTAAAAGACTGCGAGTACCCGCTGATTTCCAGAATCCTG
CATGGGCCATGTGAGAAGATCGCCAGGATCTTCCTGATGGAAGCTGACTTGGGCGTGGAAGTCCCCCATGAAGTCGCTCAGTACATTAAGTTTGAAATGCCGGTG
CTGGACAGTTTTGTTGAAAAATTAAAAGAAGAGGAAGAAAGAGAAATAATCAAACTGACCATGAAGTTCCAAGCCCTGCGTCTGACGATGCTGCAGCGCCTGGAG
CAGCTGGTGGAGGCCAAGTAA
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>RASSF4|83937|protein
MKEDCLPSSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIAWGLRRPIRLQMQDDREQVHLPSTSWMPRRPSCPLKEPSPQNGNIT
AQGPSIQPVHKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKF
RVEDGPSEFALYIVHESGERTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLE
QLVEAK
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MKEDCLPSSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIAWGLRRPIRLQMQDDREQVHLPSTSWMPRRPSCPLKEPSPQNGNIT
AQGPSIQPVHKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKF
RVEDGPSEFALYIVHESGERTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLE
QLVEAK
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (0) | 0 (0) | 1 (2) | 0 (0) | 3 (3) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 5 (5) |
Syndromic Autism Gene TopGenome-Wide Association Studies(By Ethnic Group) TopCNV Studies TopLinkage Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Spence, 2006 | USA | microsatellite-based genomic screen |  | | ASD | 133 | - | 133 | - | 280 | - | - |
| Lauritsen, 2006 | Faroe Islands | microsatellite-based genomic screen | | | autism | - | - | - | - | 12 | 44 | 56 |
Low Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies Top Microarray Studies: 3
| Reference | Source | Tissue | #Subjects (% Women) |
ADI-R | ADOS | Endo- pheno | Diagnosis | Normal Controls (% Women) |
Fold Change | Up/ Down | P/Q value | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nishimura, 2007_1 | America | lymphoblastoid cell lines | 8 (-) | | | autism with FMR1-FM | autism | 15 (-) |
1.25 | Up | 0.0000016 | |
| ||||||||||||
| Nishimura, 2007_2 | America | lymphoblastoid cell lines | 7 (-) | | | autism with dup(15q) | autism | 15 (-) |
1.39 | Up | 0.0000016 | |
| ||||||||||||
| Voineagu, 2011_1 | Unknown | 16 frontal cortex(BA9) and 13 temporal cortex(BA41 | 16 (25.00%) | | | - | autism | 16 (6.25%) |
1.05761 | Up | 36.649 | |
| ||||||||||||
Proteomics Studies:0
| Reference | Source | Tissue | Platform | #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Normal Controls(% Women) | |
|---|---|---|---|---|---|---|---|---|---|
| No Evidence. | |||||||||
NGS de novo Mutation Studies TopNGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.