Evidence Details for MTSS1
Basic Information Top
| Gene Symbol: | MTSS1 ( DKFZp781P2223,FLJ44694,KIAA0429,MIM,MIMA,MIMB ) |
|---|---|
| Gene Full Name: | metastasis suppressor 1 |
| Band: | 8q24.13 |
| Quick Links | Entrez ID:9788; OMIM: 608486; Uniprot ID:MTSS1_HUMAN; ENSEMBL ID: ENSG00000170873; HGNC ID: 20443 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>MTSS1|9788|nucleotide
ATGGAGGCTGTGATTGAGAAGGAATGCAGCGCGCTCGGAGGCCTCTTCCAGACCATCATCAGCGACATGAAGGGGAGCTATCCAGTTTGGGAAGATTTCATAAAC
AAAGCAGGAAAGCTGCAGTCCCAGCTTCGGACAACAGTAGTAGCAGCAGCTGCCTTCTTGGACGCCTTTCAGAAAGTGGCTGACATGGCCACCAACACACGTGGT
GGGACCAGGGAGATTGGATCTGCTCTCACCAGGATGTGCATGAGGCACAGAAGCATTGAAGCCAAGCTGAGGCAGTTTTCGAGCGCTTTAATTGATTGTCTGATA
AACCCACTTCAAGAACAGATGGAAGAATGGAAGAAAGTGGCCAACCAGCTGGATAAAGACCACGCAAAAGAATATAAGAAAGCCCGCCAAGAGATAAAAAAGAAG
TCCTCGGATACGCTGAAACTGCAGAAGAAAGCAAAAAAAGGGAGAGGTGATATCCAGCCTCAGTTGGACAGTGCTCTCCAAGATGTCAATGATAAGTATCTCTTA
TTGGAAGAAACAGAAAAGCAGGCTGTCCGGAAGGCTTTGATTGAAGAACGTGGCCGATTCTGTACCTTCATCTCTATGCTGCGGCCAGTGATTGAAGAAGAAATC
TCAATGCTAGGGGAAATAACCCACCTTCAGACCATCTCGGAAGATCTAAAAAGCCTGACCATGGACCCTCACAAACTGCCCTCCTCAAGTGAACAGGTGATTCTG
GACTTGAAAGGTTCTGATTACAGCTGGTCGTATCAGACGCCACCCTCTTCCCCCAGCACCACCATGTCCAGAAAGTCCAGTGTCTGCAGCAGCCTGAACAGTGTC
AACAGCAGTGACTCCCGGTCCAGCGGCTCCCACTCGCATTCCCCCAGCTCACATTACCGCTACCGCAGCTCCAACCTGGCCCAGCAGGCTCCTGTGAGGCTGTCC
AGCGTGTCCTCCCATGACTCAGGATTCATATCCCAGGATGCCTTCCAGTCCAAGTCACCATCCCCCATGCCGCCAGAGGCCCCCAACCAGTTGTCTAACGGGTTT
TCTCACTATAGTTTATCAAGTGAGTCCCACGTGGGGCCCACGGGTGCAGGCCTTTTCCCTCATTGCCTGCCTGCCTCCCGCCTGCTCCCTCGGGTCACCTCTGTC
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ATGGAGGCTGTGATTGAGAAGGAATGCAGCGCGCTCGGAGGCCTCTTCCAGACCATCATCAGCGACATGAAGGGGAGCTATCCAGTTTGGGAAGATTTCATAAAC
AAAGCAGGAAAGCTGCAGTCCCAGCTTCGGACAACAGTAGTAGCAGCAGCTGCCTTCTTGGACGCCTTTCAGAAAGTGGCTGACATGGCCACCAACACACGTGGT
GGGACCAGGGAGATTGGATCTGCTCTCACCAGGATGTGCATGAGGCACAGAAGCATTGAAGCCAAGCTGAGGCAGTTTTCGAGCGCTTTAATTGATTGTCTGATA
AACCCACTTCAAGAACAGATGGAAGAATGGAAGAAAGTGGCCAACCAGCTGGATAAAGACCACGCAAAAGAATATAAGAAAGCCCGCCAAGAGATAAAAAAGAAG
TCCTCGGATACGCTGAAACTGCAGAAGAAAGCAAAAAAAGGGAGAGGTGATATCCAGCCTCAGTTGGACAGTGCTCTCCAAGATGTCAATGATAAGTATCTCTTA
TTGGAAGAAACAGAAAAGCAGGCTGTCCGGAAGGCTTTGATTGAAGAACGTGGCCGATTCTGTACCTTCATCTCTATGCTGCGGCCAGTGATTGAAGAAGAAATC
TCAATGCTAGGGGAAATAACCCACCTTCAGACCATCTCGGAAGATCTAAAAAGCCTGACCATGGACCCTCACAAACTGCCCTCCTCAAGTGAACAGGTGATTCTG
GACTTGAAAGGTTCTGATTACAGCTGGTCGTATCAGACGCCACCCTCTTCCCCCAGCACCACCATGTCCAGAAAGTCCAGTGTCTGCAGCAGCCTGAACAGTGTC
AACAGCAGTGACTCCCGGTCCAGCGGCTCCCACTCGCATTCCCCCAGCTCACATTACCGCTACCGCAGCTCCAACCTGGCCCAGCAGGCTCCTGTGAGGCTGTCC
AGCGTGTCCTCCCATGACTCAGGATTCATATCCCAGGATGCCTTCCAGTCCAAGTCACCATCCCCCATGCCGCCAGAGGCCCCCAACCAGTTGTCTAACGGGTTT
TCTCACTATAGTTTATCAAGTGAGTCCCACGTGGGGCCCACGGGTGCAGGCCTTTTCCCTCATTGCCTGCCTGCCTCCCGCCTGCTCCCTCGGGTCACCTCTGTC
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>MTSS1|9788|protein
MEAVIEKECSALGGLFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQKVADMATNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLI
NPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKKKSSDTLKLQKKAKKGRGDIQPQLDSALQDVNDKYLLLEETEKQAVRKALIEERGRFCTFISMLRPVIEEEI
SMLGEITHLQTISEDLKSLTMDPHKLPSSSEQVILDLKGSDYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQAPVRLS
SVSSHDSGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSESHVGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPYDQ
PLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSD
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MEAVIEKECSALGGLFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQKVADMATNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLI
NPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKKKSSDTLKLQKKAKKGRGDIQPQLDSALQDVNDKYLLLEETEKQAVRKALIEERGRFCTFISMLRPVIEEEI
SMLGEITHLQTISEDLKSLTMDPHKLPSSSEQVILDLKGSDYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQAPVRLS
SVSSHDSGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSESHVGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPYDQ
PLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSD
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 0 (0) | 0 (1) | 1 (3) | 0 (0) | 1 (1) | 0 (1) | 0 (0) | 0 (0) | 0 (0) | 3 (6) |
Syndromic Autism Gene TopGenome-Wide Association Studies(By Ethnic Group) TopCNV Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Szatmari, 2007 | Europe, North America | SNP microarray |  | | ASD | 1491 | - | - | - | - | - | 0 |
Linkage Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Yonan, 2003 | USA | microsatellite-based genomic screen | |  | PDD | 345 | - | 345 | - | - | - | - |
| Liu, 2001 | USA | microsatellite-based genomic screen | | | autism, ASD | 110 | - | 110 | - | - | - | - |
| Ylisaukko-oja, 2006 | USA, Finland | microsatellite-based genomic screen | | | ASD | 314 | - | 314 | - | - | - | - |
Low Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies Top Microarray Studies: 1
| Reference | Source | Tissue | #Subjects (% Women) |
ADI-R | ADOS | Endo- pheno | Diagnosis | Normal Controls (% Women) |
Fold Change | Up/ Down | P/Q value | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ghahramani Seno, 2010_1 | Unknown | lymphoblastoid cell-line | 20 (35.00%) | | | - | AD | 22 (13.64%) |
-1.22 | Down | 0.0947 | |
| ||||||||||||
Proteomics Studies:0
| Reference | Source | Tissue | Platform | #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Normal Controls(% Women) | |
|---|---|---|---|---|---|---|---|---|---|
| No Evidence. | |||||||||
NGS de novo Mutation Studies Top| Reference | Case Number | Family Number | de novo Number | Title |
|---|---|---|---|---|
| Iossifov I, 2014 | 2508 | - | 1194 | The contribution of de novo coding mutations to autism spectrum disorder. |
NGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.