Evidence Details for TATDN2
Basic Information Top
| Gene Symbol: | TATDN2 ( KIAA0218,MGC126819,MGC126825 ) |
|---|---|
| Gene Full Name: | TatD DNase domain containing 2 |
| Band: | 3p25.3 |
| Quick Links | Entrez ID:9797; OMIM: NA; Uniprot ID:TATD2_HUMAN; ENSEMBL ID: ENSG00000157014; HGNC ID: 28988 |
| Relate to Another Database: | SFARIGene; denovo-db |
Sequences Top>TATDN2|9797|nucleotide
ATGGCGTCCGAGCGGGGCAAGGTCAAGCACAACTGGAGCAGCACGTCGGAAGGGTGTCCCCGCAAGCGCAGCTGCCTCCGGGAGCCCTGTGATGTGGCCCCCTCC
AGCCGGCCAGCTCAGAGGTCTGCGTCGCGTTCTGGAGGGCCCAGCAGCCCCAAGCGCCTGAAAGCCCAGAAGGAGGACGATGTGGCTTGCTCGCGGAGGTTATCC
TGGGGCTCATCCCGCCGCAGAAATAACTCCTCCTCCTCCTTCTCCCCACATTTCTTGGGCCCTGGTGTGGGCGGGGCCGCCTCCAAAGGCTGCCTGATTCGGAAC
ACTCGGGGGTTCCTGTCTTCAGGGGGATCCCCTCTGCGTCCTGCCAACGCCTCTTTGGAAGAAATGGCTTCTCTAGAGGAGGAAGCCTGCAGCCTTAAGGTTGAT
TCCAAAGATAGTTCTCATAACTCCACAAACTCTGAATTTGCAGCTGAAGCTGAGGGTCAGAATGATACAATTGAGGAACCCAACAAGGTCCAGAAAAGGAAGAGG
GATAGACTTCGAGACCAGGGCTCCACAATGATCTACCTGAAGGCTATCCAGGGCATCCTGGGGAAATCGATGCCAAAAAGGAAGGGAGAGGCTGCCACTCGGGCA
AAACCAAGCGCAGCAGAGCATCCCAGCCATGGAGAAGGACCAGCCAGGAGTGAAGGACCAGCCAAGACTGCAGAAGGAGCAGCCAGGAGTGTCACAGTCACTGCT
GCTCAGAAGGAGAAAGACGCAACCCCAGAGGTCAGCATGGAGGAGGATAAGACAGTGCCAGAGAGGAGCAGCTTCTATGACAGGAGAGTAGTTATAGACCCTCAA
GAGAAACCCAGTGAGGAGCCCCTTGGGGACCGAAGGACTGTCATTGACAAATGCTCTCCACCCCTAGAGTTCTTGGATGACTCTGACTCTCATTTAGAAATCCAA
AAGCATAAAGATAGGGAGGTGGTGATGGAGCACCCCTCTTCTGGAAGTGACTGGTCTGATGTTGAGGAGATCTCCACAGTCAGATTCTCTCAGGAGGAACCTGTC
TCCCTGAAACCTTCAGCCGTTCCGGAGCCTTCTTCCTTCACCACCGACTATGTCATGTACCCTCCTCATTTGTACAGTAGTCCTTGGTGTGACTACGCCAGCTAT
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ATGGCGTCCGAGCGGGGCAAGGTCAAGCACAACTGGAGCAGCACGTCGGAAGGGTGTCCCCGCAAGCGCAGCTGCCTCCGGGAGCCCTGTGATGTGGCCCCCTCC
AGCCGGCCAGCTCAGAGGTCTGCGTCGCGTTCTGGAGGGCCCAGCAGCCCCAAGCGCCTGAAAGCCCAGAAGGAGGACGATGTGGCTTGCTCGCGGAGGTTATCC
TGGGGCTCATCCCGCCGCAGAAATAACTCCTCCTCCTCCTTCTCCCCACATTTCTTGGGCCCTGGTGTGGGCGGGGCCGCCTCCAAAGGCTGCCTGATTCGGAAC
ACTCGGGGGTTCCTGTCTTCAGGGGGATCCCCTCTGCGTCCTGCCAACGCCTCTTTGGAAGAAATGGCTTCTCTAGAGGAGGAAGCCTGCAGCCTTAAGGTTGAT
TCCAAAGATAGTTCTCATAACTCCACAAACTCTGAATTTGCAGCTGAAGCTGAGGGTCAGAATGATACAATTGAGGAACCCAACAAGGTCCAGAAAAGGAAGAGG
GATAGACTTCGAGACCAGGGCTCCACAATGATCTACCTGAAGGCTATCCAGGGCATCCTGGGGAAATCGATGCCAAAAAGGAAGGGAGAGGCTGCCACTCGGGCA
AAACCAAGCGCAGCAGAGCATCCCAGCCATGGAGAAGGACCAGCCAGGAGTGAAGGACCAGCCAAGACTGCAGAAGGAGCAGCCAGGAGTGTCACAGTCACTGCT
GCTCAGAAGGAGAAAGACGCAACCCCAGAGGTCAGCATGGAGGAGGATAAGACAGTGCCAGAGAGGAGCAGCTTCTATGACAGGAGAGTAGTTATAGACCCTCAA
GAGAAACCCAGTGAGGAGCCCCTTGGGGACCGAAGGACTGTCATTGACAAATGCTCTCCACCCCTAGAGTTCTTGGATGACTCTGACTCTCATTTAGAAATCCAA
AAGCATAAAGATAGGGAGGTGGTGATGGAGCACCCCTCTTCTGGAAGTGACTGGTCTGATGTTGAGGAGATCTCCACAGTCAGATTCTCTCAGGAGGAACCTGTC
TCCCTGAAACCTTCAGCCGTTCCGGAGCCTTCTTCCTTCACCACCGACTATGTCATGTACCCTCCTCATTTGTACAGTAGTCCTTGGTGTGACTACGCCAGCTAT
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>TATDN2|9797|protein
MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLGPGVGGAASKGCLIRN
TRGFLSSGGSPLRPANASLEEMASLEEEACSLKVDSKDSSHNSTNSEFAAEAEGQNDTIEEPNKVQKRKRDRLRDQGSTMIYLKAIQGILGKSMPKRKGEAATRA
KPSAAEHPSHGEGPARSEGPAKTAEGAARSVTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVVIDPQEKPSEEPLGDRRTVIDKCSPPLEFLDDSDSHLEIQ
KHKDREVVMEHPSSGSDWSDVEEISTVRFSQEEPVSLKPSAVPEPSSFTTDYVMYPPHLYSSPWCDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYS
PNSTGSVQNTSRDMEASEEGWSQNSRSFRFSRSSEEREVKEKRTFQEEMPPRPCGGHASSSLPKSHLEPSLEEGFIDTHCHLDMLYSKLSFQGTFTKFRKIYSSS
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MASERGKVKHNWSSTSEGCPRKRSCLREPCDVAPSSRPAQRSASRSGGPSSPKRLKAQKEDDVACSRRLSWGSSRRRNNSSSSFSPHFLGPGVGGAASKGCLIRN
TRGFLSSGGSPLRPANASLEEMASLEEEACSLKVDSKDSSHNSTNSEFAAEAEGQNDTIEEPNKVQKRKRDRLRDQGSTMIYLKAIQGILGKSMPKRKGEAATRA
KPSAAEHPSHGEGPARSEGPAKTAEGAARSVTVTAAQKEKDATPEVSMEEDKTVPERSSFYDRRVVIDPQEKPSEEPLGDRRTVIDKCSPPLEFLDDSDSHLEIQ
KHKDREVVMEHPSSGSDWSDVEEISTVRFSQEEPVSLKPSAVPEPSSFTTDYVMYPPHLYSSPWCDYASYWTSSPKPSSYPSTGSSSNDAAQVGKSSRSRMSDYS
PNSTGSVQNTSRDMEASEEGWSQNSRSFRFSRSSEEREVKEKRTFQEEMPPRPCGGHASSSLPKSHLEPSLEEGFIDTHCHLDMLYSKLSFQGTFTKFRKIYSSS
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Evidence summary TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | CNV | Linkage | Association | Expression | NGS de novo | NGS Mosaic | NGS Other | Low-Scale Gene Studies | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 1 (1) | 0 (0) | 1 (3) | 0 (0) | 0 (0) | 1 (2) | 0 (0) | 0 (0) | 0 (0) | 16 (6) |
Syndromic Autism Gene TopGenome-Wide Association Studies (By Ethnic Group) Top Family Based Association Studies: 0
| Reference | Stage | Platform | #Families | Affecteds | Result | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ (range) |
|||||||
| No Evidence. | ||||||||||||
Case Control Based Association Studies: 1
| Reference | Stage | Platform | ASD Cases | Normal Controls | Result | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ | #Subjects (% Women) |
Age (range) |
|||||
| MIXED/OTHERS | ||||||||||||
| Anney RJL, 2017_3 | replication | 1369 (-) |  | | ASD | - - |
- | 137308 (-) |
- - | |||
CNV Studies TopLinkage Studies Top| Reference | Source | Method | ADI-R | ADOS | Diagnosis | Family | Individual | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| McCauley, 2005 | - | microsatellite-based genomic screen | |  | autism | 158 | - | 158 | - | 333 | - | - |
| Shao, 2002 | USA | microsatellite-based genomic screen | | | autism | 52 | - | 52 | - | 112 | - | - |
| Lauritsen, 2006 | Faroe Islands | microsatellite-based genomic screen | | | autism | - | - | - | - | 12 | 44 | 56 |
Low Scale Association Studies (by Ethnic Group) TopLarge Scale Expression Studies TopNGS de novo Mutation Studies Top| Reference | Case Number | Family Number | de novo Number | Title |
|---|---|---|---|---|
| O'Roak BJ, 2012 | 1703 | 209 | 242 | Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations. |
| De Rubeis S, 2014 | 2270 | - | 1702 | Synaptic, transcriptional and chromatin genes disrupted in autism |
NGS Mosaic SNV Studies TopNGS Other Studies Top Low Scale Gene Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.