View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | SLC35A3 | 1 | 100483370 | A | G | NM_012243 | 0.9575 | deleterious | 0 | 0.001 | 0.004 | UBE4B | 1 | 10166514 | G | A | NM_001105562 | 0.1772 | neutral | 0.49 | 0 | 0 | COL11A1 | 1 | 103352554 | C | A | NM_080630 | 0.516 | deleterious | 0 | 0.995 | 0.986 | VAV3 | 1 | 108138879 | G | C | NM_001079874 | 0.0623 | neutral | 0 | 0.02 | 0.032 | FNDC7 | 1 | 109264962 | C | T | NM_001144937 | 0.2558 | neutral | 0 | 0.992 | 0.513 | STXBP3 | 1 | 109315441 | G | A | NM_007269 | 0.715 | deleterious | 0.43 | 0.837 | 0.493 | STXBP3 | 1 | 109321932 | A | G | NM_007269 | 0.9404 | deleterious | 0.12 | 0.024 | 0.054 | AMIGO1 | 1 | 110050709 | G | A | NM_020703 | 0.0671 | neutral | 0.06 | 0 | 0.001 | EPS8L3 | 1 | 110294811 | C | T | NM_133181 | 0.0414 | neutral | 0 | 0.005 | 0.006 | CSF1 | 1 | 110456998 | C | T | NM_000757 | 0.159 | neutral | 0.01 | 0 | 0 | SLC6A17 | 1 | 110740129 | G | A | NM_001010898 | 0.9952 | deleterious | 0 | 0.975 | 0.847 | SRM | 1 | 11115912 | C | G | NM_003132 | 0.9877 | deleterious | 0.01 | 0.996 | 0.944 | MTOR | 1 | 11190804 | C | T | NM_004958 | 0.9631 | deleterious | 0.15 | 0.878 | 0.463 | KCND3 | 1 | 112525092 | C | G | NM_004980 | 0.9995 | deleterious | 0 | 1 | 1 | KCND3 | 1 | 112525095 | T | A | NM_004980 | 0.9999 | deleterious | 0 | 1 | 1 | CTTNBP2NL | 1 | 112999487 | G | A | NM_018704 | 0.9747 | deleterious | 0.05 | 1 | 0.997 | ST7L | 1 | 113084629 | T | C | NM_001308264 | 0.0379 | neutral | 0 | 0 | 0 | MTOR | 1 | 11316137 | C | T | NM_004958 | 0.9882 | deleterious | 0 | 1 | 0.996 | MOV10 | 1 | 113235478 | G | A | NM_001286072 | 0.105 | neutral | 0 | 0 | 0 | MOV10 | 1 | 113242329 | A | G | NM_001286072 | 0.8942 | deleterious | 0 | 0 | 0 |
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