View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | CHRM3 | 1 | 240072255 | A | G | NM_000740 | 0.2073 | neutral | 0.02 | 0.756 | 0.53 | CHML | 1 | 241798420 | T | A | NM_001821 | 0.8153 | deleterious | 0.18 | 0.936 | 0.787 | CNR2 | 1 | 24201929 | G | T | NM_001841 | 0.6666 | deleterious | 0.04 | 0.934 | 0.857 | PLD5 | 1 | 242383342 | T | C | NM_001195811 | 0.025 | neutral | 0.4 | 0.018 | 0.011 | PLCH2 | 1 | 2434058 | C | T | NM_001303012 | 0.0522 | neutral | 0 | 0 | 0 | ADSS | 1 | 244587309 | C | T | NM_001126 | 0.9973 | deleterious | 0 | 1 | 0.992 | HNRNPU | 1 | 245027141 | C | G | NM_004501 | 0.3637 | neutral | 0 | 0.013 | 0.02 | IFNLR1 | 1 | 24507257 | T | C | NM_170743 | 0.165 | neutral | 1 | 0.002 | 0.004 | EFCAB2 | 1 | 245250572 | G | T | NM_032328 | 0.1287 | neutral | 0 | 0.052 | 0.072 | CNST | 1 | 246810623 | C | T | NM_001139459 | 0.9785 | deleterious | 0 | 0.996 | 0.883 | AHCTF1 | 1 | 247014152 | T | C | NM_015446 | 0.0326 | neutral | 0.16 | 0 | 0 | NLRP3 | 1 | 247582253 | G | A | NM_001243133 | 0.0066 | neutral | 0 | 0 | 0 | OR2W3 | 1 | 248059630 | G | A | NM_001001957 | 0.452 | neutral | 0.01 | 0.995 | 0.964 | OR2M5 | 1 | 248309147 | G | C | NM_001004690 | 0.1768 | neutral | 0.24 | 0.971 | 0.812 | OR2M2 | 1 | 248343799 | C | G | NM_001004688 | 0.5104 | deleterious | 0 | 0.998 | 0.981 | OR2M4 | 1 | 248403015 | C | A | NM_017504 | 0.2255 | neutral | 0 | 0.988 | 0.965 | ZNF692 | 1 | 249149951 | G | A | NM_001193328 | 0.011 | neutral | 0 | 0.038 | 0.005 | PGBD2 | 1 | 249211378 | A | T | NM_170725 | 0.7939 | deleterious | 0.6 | 0.927 | 0.945 | PDIK1L | 1 | 26449034 | A | G | NM_001243532 | 0.5355 | deleterious | 0 | 0 | 0 | CATSPER4 | 1 | 26517811 | A | G | NM_198137 | 0.6495 | deleterious | 0 | 0.278 | 0.084 |
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