View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | L3MBTL1 | 20 | 42169759 | T | G | NM_015478 | 0.3042 | deleterious | 0.03 | 0.078 | 0.04 | PABPC1L | 20 | 43545506 | G | A | NM_001124756 | 0.7515 | deleterious | 0 | 0.807 | 0.092 | KCNS1 | 20 | 43723695 | C | T | NM_002251 | 0.7426 | deleterious | 0.03 | 0.998 | 0.742 | SEMG1 | 20 | 43837010 | C | T | NM_003007 | 0.1097 | neutral | 0 | 0.986 | 0.757 | SEMG2 | 20 | 43851703 | G | A | NM_003008 | 0.0287 | neutral | 0.35 | 0.035 | 0.009 | ZSWIM1 | 20 | 44511799 | G | A | NM_080603 | 0.1524 | neutral | 0 | 0.184 | 0.023 | SPATA25 | 20 | 44515322 | C | T | NM_080608 | 0.1363 | neutral | 0 | 0.265 | 0.049 | ZNF335 | 20 | 44582508 | G | A | NM_022095 | 0.0777 | neutral | 0 | 0.09 | 0.024 | SLC12A5 | 20 | 44681697 | G | A | NM_020708 | 0.9941 | deleterious | 0 | 1 | 1 | SLC35C2 | 20 | 44983771 | G | A | NM_173073 | 0.9369 | deleterious | 0 | 1 | 0.97 | SULF2 | 20 | 46292275 | T | C | NM_001161841 | 0.5254 | deleterious | 0 | 0 | 0 | PRNP | 20 | 4680118 | T | C | NM_001271561 | 0.0093 | neutral | 0 | 0 | 0 | DDX27 | 20 | 47850144 | C | T | NM_017895 | 0.5012 | neutral | 0 | 1 | 0.982 | KCNB1 | 20 | 47989527 | C | T | NM_004975 | 0.282 | neutral | 0 | 0.985 | 0.711 | ZBP1 | 20 | 56188179 | C | A | NM_001160419 | 0.0127 | neutral | 0.05 | 0.964 | 0.681 | CTSZ | 20 | 57572709 | A | G | NM_001336 | 0.978 | deleterious | 0 | 0.963 | 0.897 | ZNF831 | 20 | 57766673 | C | T | NM_178457 | 0.7861 | deleterious | 0 | 0.999 | 0.956 | CDH26 | 20 | 58559852 | G | T | NM_177980 | 0.7245 | deleterious | 0 | 1 | 0.99 | CHGB | 20 | 5903482 | G | A | NM_001819 | 0.5125 | deleterious | 0.16 | 1 | 0.99 | MCM8 | 20 | 5933079 | C | T | NM_001281520 | 0.1678 | neutral | 0 | 0 | 0 |
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