View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | C3orf52 | 3 | 111805385 | C | G | NM_001171747 | 0.0957 | neutral | 0 | 0.992 | 0.924 | SLC9C1 | 3 | 111886156 | A | C | NM_183061 | 0.3529 | neutral | 0 | 0.144 | 0.035 | CD200R1 | 3 | 112647684 | G | C | NM_170780 | 0.5995 | deleterious | 0 | 0.994 | 0.854 | SPICE1 | 3 | 113187041 | C | A | NM_144718 | 0.9392 | deleterious | 0 | 1 | 1 | GRAMD1C | 3 | 113656968 | C | T | NM_001172105 | 0.0888 | neutral | 0 | 0 | 0 | QTRTD1 | 3 | 113795683 | G | A | NM_001256836 | 0.8534 | deleterious | 0 | 1 | 0.997 | POGLUT1 | 3 | 119205717 | C | T | NM_152305 | 0.985 | deleterious | 0.01 | 1 | 0.997 | MAATS1 | 3 | 119427440 | C | T | NM_033364 | 0.1793 | neutral | 0.42 | 0.006 | 0.004 | GSK3B | 3 | 119582433 | G | T | NM_001146156 | 0.7971 | deleterious | 0.02 | 0.379 | 0.37 | STXBP5L | 3 | 120628487 | G | A | NM_001308330 | 0.0015 | neutral | 0 | 0 | 0 | FBXO40 | 3 | 121340955 | G | A | NM_016298 | 0.1245 | neutral | 0.52 | 0.982 | 0.452 | GOLGB1 | 3 | 121413433 | C | A | NM_001256488 | 0.0327 | neutral | 0 | 0 | 0 | IQCB1 | 3 | 121500697 | G | A | NM_001023571 | 0.1519 | neutral | 0 | 1 | 0.897 | KPNA1 | 3 | 122215306 | C | T | NM_002264 | 0.8911 | deleterious | 0 | 0 | 0 | PARP14 | 3 | 122422695 | A | C | NM_017554 | 0.054 | neutral | 0 | 0.138 | 0.018 | SEMA5B | 3 | 122646805 | G | A | NM_001256348 | 0.8801 | deleterious | 0 | 1 | 0.998 | PDIA5 | 3 | 122864390 | T | C | NM_006810 | 0.753 | deleterious | 0 | 0.99 | 0.952 | HEG1 | 3 | 124732039 | G | A | NM_020733 | 0.1396 | neutral | 0.12 | 0.002 | 0.004 | ALDH1L1 | 3 | 125822675 | T | G | NM_001270365 | 0.1361 | neutral | 0 | 0.097 | 0.133 | KLF15 | 3 | 126071150 | C | G | NM_014079 | 0.1694 | neutral | 0.24 | 0.435 | 0.077 |
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