View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | HMGN2 | 1 | 26800626 | G | T | NM_005517 | 0.3527 | neutral | 0.01 | 0.971 | 0.693 | RPS6KA1 | 1 | 26885393 | C | T | NM_002953 | 0.5125 | deleterious | 0 | 0.875 | 0.252 | ARID1A | 1 | 27089742 | G | A | NM_006015 | 0.0832 | neutral | 0.01 | 0.984 | 0.248 | SLC9A1 | 1 | 27440652 | C | T | NM_003047 | 0.0075 | neutral | 0.46 | 0.016 | 0.007 | MAP3K6 | 1 | 27685327 | A | G | NM_001297609 | 0.0195 | neutral | 0 | 0 | 0 | AHDC1 | 1 | 27877086 | G | A | NM_001029882 | 0.94 | deleterious | 0 | 0.128 | 0.041 | PTPRU | 1 | 29587385 | C | A | NM_001195001 | 0.9639 | deleterious | 0 | 0.876 | 0.632 | MATN1 | 1 | 31194365 | G | A | NM_002379 | 0.7368 | deleterious | 0.01 | 0.997 | 0.932 | SDC3 | 1 | 31346198 | C | T | NM_014654 | 0.7468 | deleterious | 0 | 1 | 0.999 | SDC3 | 1 | 31349764 | T | C | NM_014654 | 0.0208 | neutral | 0 | 0.001 | 0.007 | PUM1 | 1 | 31437728 | G | A | NM_001020658 | 0.9109 | deleterious | 0 | 1 | 0.988 | SERINC2 | 1 | 31905923 | C | G | NM_001199039 | 0.0745 | neutral | 0 | 0 | 0 | ADGRB2 | 1 | 32206984 | A | T | NM_001294335 | 0.4455 | neutral | 0 | 0 | 0 | TMEM39B | 1 | 32557520 | A | G | NM_018056 | 0.9962 | deleterious | 0.03 | 0.997 | 0.992 | IQCC | 1 | 32672714 | G | A | NM_018134 | 0.8278 | deleterious | 0 | 0.877 | 0.343 | HDAC1 | 1 | 32790137 | C | T | NM_004964 | 0.6724 | deleterious | 0.03 | 0.946 | 0.863 | KIAA1522 | 1 | 33236926 | C | G | NM_001198972 | 0.1193 | neutral | 0.28 | 0.042 | 0.031 | HPCA | 1 | 33354602 | C | T | NM_002143 | 0.5067 | deleterious | 0.05 | 0.024 | 0.008 | ARHGEF16 | 1 | 3385486 | C | T | NM_014448 | 0.9962 | deleterious | 0.01 | 1 | 0.998 | ZMYM6 | 1 | 35453426 | C | T | NM_007167 | 0.2526 | neutral | 0.25 | 0.82 | 0.067 |
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