View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | OXTR | 3 | 8794707 | G | C | NM_000916 | 0.1384 | neutral | 0.21 | 0.016 | 0.011 | CGGBP1 | 3 | 88104967 | G | A | NM_001008390 | 0.6352 | deleterious | 0 | 0.989 | 0.193 | EPHA3 | 3 | 89480428 | C | A | NM_005233 | 0.0609 | neutral | 0 | 1 | 0.999 | RAD18 | 3 | 8983216 | G | C | NM_020165 | 0.0141 | neutral | 0.24 | 0.042 | 0.021 | SRGAP3 | 3 | 9036106 | C | T | NM_001033117 | 0.8975 | deleterious | 0.1 | 0.999 | 0.982 | SRGAP3 | 3 | 9089078 | C | T | NM_001033117 | 0.9457 | deleterious | 0.66 | 0.995 | 0.956 | SRGAP3 | 3 | 9106142 | G | A | NM_001033117 | 0.9473 | deleterious | 0 | 1 | 0.967 | SETD5 | 3 | 9477532 | A | G | NM_001080517 | 0.9636 | deleterious | 0 | 0.997 | 0.98 | SETD5 | 3 | 9486949 | G | A | NM_001292043 | 0.0772 | neutral | 0 | 0 | 0 | SETD5 | 3 | 9517219 | G | C | NM_001292043 | 0.7084 | deleterious | 0 | 0 | 0 | SETD5 | 3 | 9517475 | T | G | NM_001292043 | 0.4971 | deleterious | 0 | 0 | 0 | OR5AC2 | 3 | 97806680 | C | T | NM_054106 | 0.237 | neutral | 0.21 | 0.007 | 0.013 | OR5H2 | 3 | 98002470 | G | A | NM_001005482 | 0.0861 | neutral | 0 | 1 | 1 | ARPC4-TTLL3 | 3 | 9854936 | T | A | NM_001198793 | 0.038 | neutral | 1 | 0 | 0 | DCBLD2 | 3 | 98600385 | T | C | NM_080927 | 0.5922 | deleterious | 0.07 | 1 | 0.999 | ARPC4-TTLL3 | 3 | 9870673 | A | C | NM_001198793 | 0.7743 | deleterious | 0 | 0.217 | 0.188 | ARPC4-TTLL3 | 3 | 9871026 | C | T | NM_001198793 | 0.0277 | neutral | 0 | 0.087 | 0.039 | ADH1B | 4 | 100237436 | T | G | NM_001286650 | 0.0005 | neutral | 0 | 0 | 0 | WDR1 | 4 | 10117822 | C | T | NM_005112 | 0.4777 | deleterious | 0 | 0 | 0 | MANBA | 4 | 103644163 | G | C | NM_005908 | 0.9908 | deleterious | 0 | 0.999 | 0.987 |
|---|