View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | FAT2 | 5 | 150948279 | G | A | NM_001447 | 0.7741 | deleterious | 0.03 | 1 | 0.928 | G3BP1 | 5 | 151166215 | G | A | NM_005754 | 0.0742 | neutral | 0 | 0 | 0 | G3BP1 | 5 | 151166276 | G | A | NM_005754 | 0.0793 | neutral | 0 | 0 | 0 | G3BP1 | 5 | 151173742 | A | G | NM_005754 | 0.0757 | neutral | 0 | 0 | 0 | G3BP1 | 5 | 151180332 | G | A | NM_005754 | 0.0742 | neutral | 0 | 0 | 0 | GRIA1 | 5 | 153030052 | G | A | NM_001258020 | 0.1694 | neutral | 0 | 0 | 0 | GRIA1 | 5 | 153144076 | G | A | NM_001258020 | 0.9628 | deleterious | 0 | 0 | 0 | GEMIN5 | 5 | 154307070 | G | C | NM_001252156 | 0.0053 | neutral | 0 | 0.996 | 0.919 | ITK | 5 | 156649954 | C | T | NM_005546 | 0.8587 | deleterious | 0.01 | 0.938 | 0.545 | ITK | 5 | 156679654 | G | A | NM_005546 | 0.4986 | deleterious | 0.61 | 0 | 0 | CYFIP2 | 5 | 156819928 | G | A | NM_001291721 | 0.988 | deleterious | 0 | 0 | 0 | PWWP2A | 5 | 159520099 | G | A | NM_001130864 | 0.92 | deleterious | 0.1 | 0.919 | 0.401 | ATP10B | 5 | 160042903 | G | T | NM_025153 | 0.4446 | neutral | 0 | 0.989 | 0.902 | ATP10B | 5 | 160049576 | G | A | NM_025153 | 0.9897 | deleterious | 0 | 1 | 0.999 | GABRG2 | 5 | 161522557 | G | A | NM_000816 | 0.7671 | deleterious | 0 | 0.112 | 0.064 | GABRG2 | 5 | 161524765 | C | T | NM_000816 | 0.8666 | deleterious | 0 | 1 | 0.999 | GABRG2 | 5 | 161576159 | G | A | NM_000816 | 0.8666 | deleterious | 0 | 0.998 | 0.954 | TENM2 | 5 | 167474474 | A | G | NM_001122679 | 0.4344 | neutral | 0 | 0.858 | 0.334 | WWC1 | 5 | 167887718 | C | A | NM_001161661 | 0.0028 | neutral | 0.37 | 0.037 | 0.013 | SLIT3 | 5 | 168180047 | C | T | NM_001271946 | 0.4169 | neutral | 0 | 0 | 0 |
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