View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | RANBP17 | 5 | 170597192 | C | T | NM_022897 | 0.4825 | neutral | 0.18 | 0.827 | 0.172 | FBXW11 | 5 | 171337706 | G | C | NM_033645 | 0.0088 | neutral | 0 | 0.001 | 0.005 | HIGD2A | 5 | 175816383 | G | A | NM_138820 | 0.1176 | neutral | 0.31 | 0.081 | 0.028 | FAF2 | 5 | 175921055 | A | G | NM_014613 | 0.9066 | deleterious | 0.19 | 0.469 | 0.223 | UIMC1 | 5 | 176334136 | G | C | NM_001199297 | 0.2923 | neutral | 0 | 0 | 0 | UIMC1 | 5 | 176409574 | G | A | NM_001199297 | 0.2293 | neutral | 0 | 0 | 0 | NSD1 | 5 | 176638672 | T | G | NM_022455 | 0.3132 | neutral | 0 | 0.995 | 0.88 | NSD1 | 5 | 176684041 | T | C | NM_172349 | 0.8708 | deleterious | 0 | 1 | 1 | SLC34A1 | 5 | 176813540 | A | G | NM_001167579 | 0.873 | deleterious | 0 | 0 | 0 | SLC34A1 | 5 | 176824788 | C | T | NM_003052 | 0.9993 | deleterious | 0 | 0.996 | 0.967 | ZNF354B | 5 | 178310216 | T | C | NM_058230 | 0.1524 | neutral | 0.03 | 0.997 | 0.879 | GRM6 | 5 | 178413163 | G | C | NM_000843 | 0.4854 | neutral | 0.74 | 0.881 | 0.51 | RUFY1 | 5 | 179023604 | G | A | NM_001040451 | 0.0301 | neutral | 0 | 0 | 0 | MGAT4B | 5 | 179225962 | G | A | NM_014275 | 0.6835 | deleterious | 0.05 | 0.997 | 0.548 | BTNL9 | 5 | 180485372 | T | A | NM_152547 | 0.0379 | neutral | 0.4 | 0.103 | 0.065 | CDH18 | 5 | 19473795 | C | T | NM_001291956 | 0.2473 | neutral | 0 | 0 | 0 | PRDM9 | 5 | 23522893 | T | C | NM_001310214 | 0.5218 | deleterious | 0 | 0 | 0 | CDH9 | 5 | 26885797 | T | C | NM_016279 | 0.7245 | deleterious | 0 | 0.384 | 0.451 | PDCD6 | 5 | 306768 | G | A | NM_001267558 | 0.6784 | deleterious | 0 | 0 | 0 | PDZD2 | 5 | 32074487 | G | A | NM_178140 | 0.0035 | neutral | 0 | 0 | 0 |
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