View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | ADAM22 | 7 | 87760687 | G | A | NM_004194 | 0.5125 | deleterious | 0 | 0 | 0 | NXPH1 | 7 | 8790890 | A | G | NM_152745 | 0.9909 | deleterious | 0.01 | 1 | 0.988 | ZNF804B | 7 | 88963885 | A | T | NM_181646 | 0.3791 | neutral | 0.11 | 0.933 | 0.518 | CDK14 | 7 | 90355990 | G | A | NM_001287136 | 0.9166 | deleterious | 0 | 0 | 0 | AKAP9 | 7 | 91630490 | A | G | NM_005751 | 0.1093 | neutral | 0.28 | 0.347 | 0.085 | AKAP9 | 7 | 91691610 | T | A | NM_005751 | 0.6974 | deleterious | 0 | 0.999 | 0.98 | RBM48 | 7 | 92161752 | T | G | NM_032120 | 0.9126 | deleterious | 0.01 | 0.995 | 0.94 | FAM133B | 7 | 92207484 | C | T | NM_001040057 | 0.1775 | neutral | 0 | 0 | 0 | SAMD9 | 7 | 92734051 | C | T | NM_001193307 | 0.2592 | neutral | 0 | 0 | 0 | COL1A2 | 7 | 94039077 | C | T | NM_000089 | 0.9375 | deleterious | 0 | 1 | 0.997 | COL1A2 | 7 | 94042413 | G | C | NM_000089 | 0.9998 | deleterious | 0 | 1 | 1 | PEG10 | 7 | 94293229 | G | A | NM_001040152 | 0.3664 | neutral | 0.04 | 0 | 0 | ADAP1 | 7 | 944768 | C | T | NM_006869 | 0.605 | deleterious | 0.18 | 0.998 | 0.826 | DYNC1I1 | 7 | 95661998 | A | G | NM_001135557 | 0.1446 | neutral | 0 | 0.002 | 0.006 | SLC25A13 | 7 | 95750561 | T | G | NM_014251 | 0.1901 | neutral | 0 | 0.017 | 0.004 | SDHAF3 | 7 | 96747192 | T | C | NM_020186 | 0.1992 | neutral | 0 | 0.777 | 0.396 | LMTK2 | 7 | 97816289 | A | G | NM_014916 | 0.9165 | deleterious | 0.08 | 0.728 | 0.678 | LMTK2 | 7 | 97821294 | C | T | NM_014916 | 0.9885 | deleterious | 0 | 1 | 0.999 | LMTK2 | 7 | 97823256 | C | A | NM_014916 | 0.7966 | deleterious | 0.18 | 0.278 | 0.034 | BAIAP2L1 | 7 | 97923404 | G | A | NM_018842 | 0.0393 | neutral | 0.3 | 0.003 | 0.003 |
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