View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | RFX3 | 9 | 3263017 | G | T | NM_001282116 | 0.1153 | neutral | 0 | 0 | 0 | NFX1 | 9 | 33366682 | G | A | NM_002504 | 0.0391 | neutral | 0.58 | 0.58 | 0.182 | UBAP2 | 9 | 33948584 | G | A | NM_018449 | 0.9606 | deleterious | 0.09 | 1 | 0.997 | KIF24 | 9 | 34259682 | C | T | NM_194313 | 0.9406 | deleterious | 0 | 1 | 1 | FAM219A | 9 | 34401083 | T | A | NM_001184945 | 0.9849 | deleterious | 0 | 1 | 0.999 | FAM205A | 9 | 34728650 | C | G | NM_001141917 | 0.0079 | neutral | 0.16 | 0.001 | 0.001 | VCP | 9 | 35057454 | C | T | NM_007126 | 0.9991 | deleterious | 0.07 | 0.719 | 0.216 | VCP | 9 | 35061615 | T | G | NM_007126 | 0.9991 | deleterious | 0 | 0.99 | 0.954 | UNC13B | 9 | 35377646 | T | G | NM_006377 | 0.7956 | deleterious | 0.01 | 0.935 | 0.684 | RUSC2 | 9 | 35559246 | T | G | NM_001135999 | 0.8135 | deleterious | 0 | 0 | 0 | FAM166B | 9 | 35563361 | G | A | NM_001099951 | 0.4857 | deleterious | 0 | 0.999 | 0.862 | CREB3 | 9 | 35736692 | C | G | NM_006368 | 0.0614 | neutral | 0.04 | 0.02 | 0.025 | CCIN | 9 | 36169894 | A | G | NM_005893 | 0.3147 | neutral | 0 | 0.956 | 0.899 | CCIN | 9 | 36170719 | G | C | NM_005893 | 0.8213 | deleterious | 1 | 0.999 | 0.997 | GNE | 9 | 36246115 | G | A | NM_001190384 | 0.8697 | deleterious | 0 | 1 | 0.917 | MELK | 9 | 36583642 | A | G | NM_001256685 | 0.765 | deleterious | 0 | 0.985 | 0.907 | PAX5 | 9 | 37033983 | C | G | NM_001280547 | 0.9922 | deleterious | 0 | 0 | 0 | DCAF10 | 9 | 37860178 | T | G | NM_001286810 | 0.0017 | neutral | 0 | 0 | 0 | SHB | 9 | 37974819 | T | C | NM_003028 | 0.0707 | neutral | 0.44 | 0.99 | 0.868 | GLIS3 | 9 | 4118634 | G | C | NM_152629 | 0.13 | neutral | 1 | 0.297 | 0.081 |
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