View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | HTR7 | 10 | 92509055 | G | A | NM_000872 | 0.6869 | deleterious | 0.38 | 0.074 | 0.038 | CYP26A1 | 10 | 94836446 | A | G | NM_057157 | 0.1915 | neutral | 0 | 0 | 0 | MYOF | 10 | 95079735 | G | C | NM_133337 | 0.0178 | neutral | 0 | 0.918 | 0.835 | HELLS | 10 | 96322608 | A | G | NM_001289068 | 0.0088 | neutral | 0 | 0 | 0 | CYP2C18 | 10 | 96447920 | C | T | NM_000772 | 0.2488 | neutral | 0 | 1 | 0.973 | CYP2C8 | 10 | 96827403 | T | C | NM_001198853 | 0.0062 | neutral | 0 | 0 | 0 | SORBS1 | 10 | 97194397 | C | G | NM_001034954 | 0.7362 | deleterious | 0 | 0.997 | 0.956 | ALDH18A1 | 10 | 97371016 | C | G | NM_001017423 | 0.0288 | neutral | 0.02 | 0.005 | 0.007 | TCTN3 | 10 | 97446866 | C | T | NM_001143973 | 0.016 | neutral | 0 | 0.03 | 0.01 | DNTT | 10 | 98064396 | C | T | NM_001017520 | 0.9657 | deleterious | 0 | 1 | 1 | C10orf12 | 10 | 98741973 | A | G | NM_015652 | 0.4583 | neutral | 0.19 | 0.975 | 0.591 | C10orf12 | 10 | 98744251 | G | C | NM_015652 | 0.1509 | neutral | 0.26 | 0.367 | 0.11 | ARHGAP19 | 10 | 99024633 | G | A | NM_001256423 | 0.5524 | deleterious | 0 | 1 | 0.991 | RRP12 | 10 | 99160118 | C | T | NM_001145114 | 0.0217 | neutral | 0 | 0.861 | 0.146 | HOGA1 | 10 | 99361725 | G | A | NM_001134670 | 0.9278 | deleterious | 0 | 1 | 0.985 | PI4K2A | 10 | 99426263 | C | T | NM_018425 | 0.928 | deleterious | 0.04 | 1 | 0.999 | CNTN5 | 11 | 100168410 | T | A | NM_175566 | 0.017 | neutral | 0 | 0 | 0 | TRPC6 | 11 | 101340218 | C | A | NM_004621 | 0.009 | neutral | 0.36 | 0 | 0 | MUC6 | 11 | 1016042 | C | G | NM_005961 | 0.0247 | neutral | 0.61 | 0 | 0 | MUC6 | 11 | 1016288 | G | C | NM_005961 | 0.0062 | neutral | 0.38 | 0.271 | 0.073 |
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