View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | RSF1 | 11 | 77458112 | A | G | NM_016578 | 0.8782 | deleterious | 0.01 | 0.999 | 0.991 | USP35 | 11 | 77921348 | G | A | NM_020798 | 0.3496 | neutral | 0 | 0 | 0 | GAB2 | 11 | 77938015 | C | G | NM_012296 | 0.1352 | neutral | 0.41 | 0 | 0 | GAB2 | 11 | 77961261 | C | T | NM_012296 | 0.1329 | neutral | 0.5 | 0 | 0 | RIC3 | 11 | 8148296 | T | C | NM_024557 | 0.05 | neutral | 0 | 0.996 | 0.99 | RIC3 | 11 | 8190433 | T | C | NM_001135109 | 0.0381 | neutral | 0 | 0.002 | 0.01 | PRCP | 11 | 82536081 | C | A | NM_005040 | 0.7626 | deleterious | 0 | 1 | 0.999 | CCDC90B | 11 | 82989819 | T | C | NM_001286116 | 0.0566 | neutral | 0 | 0 | 0 | DLG2 | 11 | 83497765 | G | C | NM_001142700 | 0.0032 | neutral | 0 | 0.214 | 0.305 | CD151 | 11 | 837476 | G | C | NM_001039490 | 0.2396 | neutral | 0 | 0 | 0 | CCDC81 | 11 | 86126337 | T | G | NM_021827 | 0.234 | neutral | 0 | 1 | 0.992 | TYR | 11 | 88911734 | C | A | NM_000372 | 0.8764 | deleterious | 0 | 0.973 | 0.911 | TYR | 11 | 88961072 | C | A | NM_000372 | 0.8947 | deleterious | 0 | 0.001 | 0.004 | SCUBE2 | 11 | 9111335 | C | T | NM_001170690 | 0.0656 | neutral | 0 | 0.919 | 0.555 | DENND5A | 11 | 9163520 | C | T | NM_015213 | 0.9726 | deleterious | 0.01 | 1 | 1 | DENND5A | 11 | 9172264 | T | C | NM_001243254 | 0.8683 | deleterious | 0.13 | 0.061 | 0.102 | FAT3 | 11 | 92087350 | A | C | NM_001008781 | 0.0931 | neutral | 0 | 0.554 | 0.203 | FAT3 | 11 | 92258103 | A | G | NM_001008781 | 0.8015 | deleterious | 0 | 0.999 | 0.997 | FAT3 | 11 | 92533228 | G | A | NM_001008781 | 0.9829 | deleterious | 0 | 1 | 0.998 | FAT3 | 11 | 92600180 | G | A | NM_001008781 | 0.5186 | deleterious | 0 | 0.841 | 0.318 |
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