View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | KAZN | 1 | 15430600 | G | A | NM_201628 | 0.8794 | deleterious | 0 | 1 | 0.999 | ATP8B2 | 1 | 154317610 | A | G | NM_020452 | 0.9271 | deleterious | 0 | 1 | 0.999 | ATP8B2 | 1 | 154321590 | G | A | NM_020452 | 0.1251 | neutral | 0 | 0.49 | 0.082 | TDRD10 | 1 | 154493911 | C | T | NM_001098475 | 0.1705 | neutral | 0.14 | 0.408 | 0.058 | RUSC1 | 1 | 155296911 | C | A | NM_001278229 | 0.0448 | neutral | 0 | 0 | 0 | YY1AP1 | 1 | 155630566 | G | C | NM_139121 | 0.0929 | neutral | 0 | 0 | 0 | GON4L | 1 | 155735530 | A | C | NM_001282856 | 0.0171 | neutral | 0 | 0 | 0 | ARHGEF2 | 1 | 155932442 | G | A | NM_004723 | 0.3328 | neutral | 0 | 0 | 0 | MEF2D | 1 | 156446863 | G | A | NM_001271629 | 0.9783 | deleterious | 0 | 1 | 0.996 | MEF2D | 1 | 156452416 | C | T | NM_001271629 | 0.9983 | deleterious | 0 | 1 | 0.989 | MEF2D | 1 | 156452417 | G | A | NM_001271629 | 0.9819 | deleterious | 0 | 1 | 0.999 | IQGAP3 | 1 | 156536205 | C | T | NM_178229 | 0.7899 | deleterious | 0.01 | 1 | 0.993 | PEAR1 | 1 | 156883034 | C | T | NM_001080471 | 0.7847 | deleterious | 0.43 | 1 | 0.997 | ETV3 | 1 | 157094760 | G | C | NM_001145312 | 0.9441 | deleterious | 0 | 1 | 0.998 | CD1A | 1 | 158226779 | G | A | NM_001763 | 0.009 | neutral | 0.08 | 0.973 | 0.476 | SPTA1 | 1 | 158585162 | C | T | NM_003126 | 0.4875 | neutral | 0 | 0.014 | 0.015 | PYHIN1 | 1 | 158906752 | A | G | NM_152501 | 0.026 | neutral | 0 | 0.101 | 0.105 | OR10J3 | 1 | 159283723 | C | T | NM_001004467 | 0.0017 | neutral | 0.06 | 0.478 | 0.365 | APCS | 1 | 159558174 | C | G | NM_001639 | 0.9948 | deleterious | 0 | 1 | 0.999 | CFAP45 | 1 | 159846398 | C | T | NM_012337 | 0.0134 | neutral | 0 | 0.002 | 0.001 |
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