View Variant Prediction
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.
| Gene Symbol | Chr | Position | refNT | altNT | transcript | iFish Probability | iFish Prediction | SIFT | Polyhen2_HDIV | Polyhen2_HVAR | SLAMF9 | 1 | 159922117 | C | T | NM_033438 | 0.9552 | deleterious | 0 | 1 | 1 | ATP1A4 | 1 | 160125943 | C | T | NM_144699 | 0.8545 | deleterious | 0 | 0.991 | 0.986 | COPA | 1 | 160281685 | T | C | NM_001098398 | 0.318 | neutral | 0.47 | 0.041 | 0.081 | FBLIM1 | 1 | 16096936 | C | T | NM_001024215 | 0.3235 | neutral | 0 | 0.896 | 0.699 | FBLIM1 | 1 | 16101147 | T | G | NM_001024216 | 0.0885 | neutral | 0.51 | 0.008 | 0.002 | USP21 | 1 | 161130734 | C | T | NM_001014443 | 0.1753 | neutral | 0 | 0 | 0 | B4GALT3 | 1 | 161141673 | C | T | NM_001199873 | 0.3312 | neutral | 0 | 0 | 0 | OLFML2B | 1 | 161989809 | G | A | NM_001297713 | 0.0776 | neutral | 0 | 0 | 0 | SPEN | 1 | 16235920 | A | C | NM_015001 | 0.9211 | deleterious | 0 | 0.986 | 0.759 | SPEN | 1 | 16261227 | G | C | NM_015001 | 0.1728 | neutral | 0.3 | 0.783 | 0.636 | ZBTB17 | 1 | 16269685 | C | T | NM_001242884 | 0.0318 | neutral | 0 | 0.999 | 0.9 | DDR2 | 1 | 162740230 | C | T | NM_001014796 | 0.2952 | neutral | 0 | 0 | 0 | CLCNKA | 1 | 16352629 | A | G | NM_001042704 | 0.2619 | neutral | 0 | 0.002 | 0.008 | CLCNKB | 1 | 16375706 | G | A | NM_000085 | 0.4111 | neutral | 0 | 0 | 0 | CLCNKB | 1 | 16376358 | C | G | NM_001165945 | 0.2456 | neutral | 0.21 | 0.002 | 0.012 | PBX1 | 1 | 164769051 | G | C | NM_001204961 | 0.9404 | deleterious | 0.04 | 0.755 | 0.593 | PBX1 | 1 | 164790805 | C | T | NM_001204963 | 0.7503 | deleterious | 0.13 | 0.812 | 0.419 | ARHGEF19 | 1 | 16525147 | G | C | NM_153213 | 0.9777 | deleterious | 0.17 | 0.999 | 0.974 | POU2F1 | 1 | 167384806 | C | T | NM_001198786 | 0.287 | neutral | 0 | 0.997 | 0.709 | MPZL1 | 1 | 167745396 | C | T | NM_003953 | 0.1398 | neutral | 0.04 | 0.594 | 0.184 |
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