Detail Information of AutLD0000090
1. Sample AND Method Top
| Ancestry | ADI-R | ADOS | Diagnosis | Family | Individual | Reference | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Caucasion |  |  | autism | 115 | - | 115 | - | - | - | - | Buxbaum, 2004 | |
| Country: | USA | |||||||||||
| Marker Number: | 335 | |||||||||||
| Platform: | - | |||||||||||
| Method: | microsatellite-based genomic screen | |||||||||||
| Software Algorithm: | Genehunter | |||||||||||
| Band: | 10q23.31 | |||||||||||
| Marker: | D10S2327 | |||||||||||
| Region: | Chr10: 89600000 - 92900000 | |||||||||||
2. Related Syndromic Genes TopAbbreviations: AD, autosomal dominant; AR, autosomal recessive; ASD, autism spectrum disorder; ID, intellectual disability; XL, X linked.
| Gene ID | Gene Symbol | Inheritance | Evidence Level |
|---|---|---|---|
| AutG5728 | PTEN | AD | Level 3: The gene has been reported in many families with ASD/autistic features, but the disorder hasn't been a generally acknowledged ASD related disorder. |
3. Related Non-syndromic Genes Top| Gene ID | Gene Symbol | Evidence Score | Total Score | |||||
|---|---|---|---|---|---|---|---|---|
| Low-Scale Association | GWAS | Low-Scale Single Gene | Expression | CNV | Linkage | |||
| AutG5728 | PTEN | 0 | 0 | 3 | 0 | 1 | 1 | 78 |
| AutG57559 | STAMBPL1 | 0 | 0 | 0 | 2 | 1 | 1 | 4 |
| AutG355 | FAS | 0 | 0 | 0 | 1 | 1 | 1 | 3 |
| AutG3437 | IFIT3 | 0 | 0 | 0 | 1 | 1 | 1 | 3 |