Detail Information of AutLD0000097
1. Sample AND Method Top
| Ancestry | ADI-R | ADOS | Diagnosis | Family | Individual | Reference | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Caucasion |  |  | autism | 26 | - | 26 | - | - | - | - | Ma, 2007 | |
| Country: | USA | |||||||||||
| Marker Number: | 11665 | |||||||||||
| Platform: | Affymetrix GeneChip Human Mapping 10K array | |||||||||||
| Method: | SNP-based genomic screen | |||||||||||
| Software Algorithm: | Merlin | |||||||||||
| Band: | 5q23.2 | |||||||||||
| Marker: | rs2078477 | |||||||||||
| Region: | Chr5: 121500000 - 127300000 | |||||||||||
2. Related Syndromic Genes TopAbbreviations: AD, autosomal dominant; AR, autosomal recessive; ASD, autism spectrum disorder; ID, intellectual disability; XL, X linked.
| Gene ID | Gene Symbol | Inheritance | Evidence Level |
|---|---|---|---|
| AutG501 | ALDH7A1 | AR | Level 3: The gene has been reported in many families with ASD/autistic features, but the disorder hasn't been a generally acknowledged ASD related disorder. |
3. Related Non-syndromic Genes Top| Gene ID | Gene Symbol | Evidence Score | Total Score | |||||
|---|---|---|---|---|---|---|---|---|
| Low-Scale Association | GWAS | Low-Scale Single Gene | Expression | CNV | Linkage | |||
| AutG5480 | PPIC | 0 | 0 | 0 | 1 | 1 | 1 | 3 |
| AutG6643 | SNX2 | 0 | 0 | 0 | 1 | 1 | 1 | 3 |