Detail Information of AutLD0000149
1. Sample AND Method Top
| Ancestry | ADI-R | ADOS | Diagnosis | Family | Individual | Reference | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Simplex | Multiplex | Control | Affected | Control | Total | ||||||
| Caucasion |  | | ASD | 61 | 61 | - | - | 61 | 149 | 210 | Guerini, 2010 | |
| Country: | Italy | |||||||||||
| Marker Number: | 7 | |||||||||||
| Platform: | - | |||||||||||
| Method: | microsatellite-based genomic screen, SNP-based genomic screen | |||||||||||
| Software Algorithm: | LINKAGE | |||||||||||
| Band: | 6p22.2 | |||||||||||
| Marker: | D6S2239 | |||||||||||
| Region: | Chr6: 23500000 - 26100000 | |||||||||||
2. Related Syndromic Genes TopAbbreviations: AD, autosomal dominant; AR, autosomal recessive; ASD, autism spectrum disorder; ID, intellectual disability; XL, X linked.
| Gene ID | Gene Symbol | Inheritance | Evidence Level |
|---|---|---|---|
| AutG7915 | ALDH5A1 | AR | Level 3: The gene has been reported in many families with ASD/autistic features, but the disorder hasn't been a generally acknowledged ASD related disorder. |
3. Related Non-syndromic Genes Top| Gene ID | Gene Symbol | Evidence Score | Total Score | |||||
|---|---|---|---|---|---|---|---|---|
| Low-Scale Association | GWAS | Low-Scale Single Gene | Expression | CNV | Linkage | |||
| AutG57380 | MRS2 | 0 | 0 | 0 | 1 | 1 | 1 | 3 |
| AutG9750 | FAM65B | 0 | 0 | 0 | 1 | 1 | 1 | 3 |