View the Detailed Mosaic Information from PubMed ID: 27632392
| Gene ID | Gene Symbol | Chr | Position |
|---|---|---|---|
| 2262 | GPC5 | 13 | 92345513 |
| Ref | Alt | Genotype | Validated Method |
| T | C | mosaic | Sanger Sequencing and Pyrosequencing |
| iFish Probablity | iFish Prediction | SIFT | Phylop |
| 0.9758 | deleterious | 0 | 8.042 |
| Polyphen2_HDIV | Polyphen2_HVAR | MutationAssessor | GERP_RS |
| 0.999 | 0.978 | 2.885 | 5.07 |
| dScore | CpG | Hydropathicity | Polarity |
| 1.983 | -2.6 | 2.9 |
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes. At the same time, iFish alsoprovides functional annotations from other classifiers such as: SIFT, Polyphen2, and MutationTaster2.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.