View the Detailed Mosaic Information from PubMed ID: 28503910
| Gene ID | Gene Symbol | Chr | Position |
|---|---|---|---|
| 23304 | UBR2 | 6 | 42613210 |
| Ref | Alt | Genotype | Validated Method |
| G | A | mosaic | PASM |
| SSC ID | WES Depth | WES Alt Count | PASM Depth |
| 12399.s1 | 90 | 8 | 14726 |
| PASM Maf | PASM MAF 95%CI lowerbound | PASM MAF 95%CI upperbound | Location |
| 0.22 | 0.213 | 0.227 | exonic |
| iFish Probablity | iFish Prediction | SIFT | Phylop |
| 0.5125 | deleterious | 9.303 | |
| Polyphen2_HDIV | Polyphen2_HVAR | MutationAssessor | GERP_RS |
| 0.999 | 0.994 | 2.71 | 5.6 |
| dScore | CpG | Hydropathicity | Polarity |
| 1.278 | 0.6 | 0.8 |
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes. At the same time, iFish alsoprovides functional annotations from other classifiers such as: SIFT, Polyphen2, and MutationTaster2.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.