View the Detailed Mosaic Information from PubMed ID: 27632392
| Gene ID | Gene Symbol | Chr | Position |
|---|---|---|---|
| 27237 | ARHGEF16 | 1 | 3385486 |
| Ref | Alt | Genotype | Validated Method |
| C | T | mosaic | Sanger Sequencing and Pyrosequencing |
| iFish Probablity | iFish Prediction | SIFT | Phylop |
| 0.9962 | deleterious | 0.01 | 4.07 |
| Polyphen2_HDIV | Polyphen2_HVAR | MutationAssessor | GERP_RS |
| 1 | 0.998 | 2.645 | 2.39 |
| dScore | CpG | Hydropathicity | Polarity |
| 4.102 | 3.6 | -5.1 |
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes. At the same time, iFish alsoprovides functional annotations from other classifiers such as: SIFT, Polyphen2, and MutationTaster2.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.