View the Detailed Mosaic Information from PubMed ID: 28503910
| Gene ID | Gene Symbol | Chr | Position |
|---|---|---|---|
| 29926 | GMPPA | 2 | 220367114 |
| Ref | Alt | Genotype | Validated Method |
| C | T | mosaic | PASM |
| SSC ID | WES Depth | WES Alt Count | PASM Depth |
| 11573.p1 | 65 | 7 | 8175 |
| PASM Maf | PASM MAF 95%CI lowerbound | PASM MAF 95%CI upperbound | Location |
| 0.146 | 0.138 | 0.154 | exonic |
| iFish Probablity | iFish Prediction | SIFT | Phylop |
| 0.2941 | neutral | 0.01 | 0.879 |
| Polyphen2_HDIV | Polyphen2_HVAR | MutationAssessor | GERP_RS |
| 0.971 | 0.75 | 1.65 | 3.55 |
| dScore | CpG | Hydropathicity | Polarity |
| 2.384 | 2.6 | -2.9 |
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes. At the same time, iFish alsoprovides functional annotations from other classifiers such as: SIFT, Polyphen2, and MutationTaster2.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.