View the Detailed Mosaic Information from PubMed ID: 28503910
| Gene ID | Gene Symbol | Chr | Position |
|---|---|---|---|
| 57512 | GPR158 | 10 | 25887707 |
| Ref | Alt | Genotype | Validated Method |
| A | G | mosaic | PASM |
| SSC ID | WES Depth | WES Alt Count | PASM Depth |
| 12063.s1 | 55 | 6 | 14001 |
| PASM Maf | PASM MAF 95%CI lowerbound | PASM MAF 95%CI upperbound | Location |
| 0.03 | 0.027 | 0.033 | exonic |
| iFish Probablity | iFish Prediction | SIFT | Phylop |
| 0.1342 | neutral | 0.52 | 3.223 |
| Polyphen2_HDIV | Polyphen2_HVAR | MutationAssessor | GERP_RS |
| 0.06 | 0.006 | 2.455 | 2.93 |
| dScore | CpG | Hydropathicity | Polarity |
| 0.564 | -0.6 | -0.8 |
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes. At the same time, iFish alsoprovides functional annotations from other classifiers such as: SIFT, Polyphen2, and MutationTaster2.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.