View the Detailed Mosaic Information from PubMed ID: 28867142
| Gene ID | Gene Symbol | Chr | Position |
|---|---|---|---|
| 79784 | MYH14 | 19 | 50753076 |
| Ref | Alt | Genotype | Validated Method |
| G | A | Mosaic | |
| SSC ID | WES Depth | WES Alt Count | PASM Depth |
| 11703.p1 | 86 | ||
| PASM Maf | PASM MAF 95%CI lowerbound | PASM MAF 95%CI upperbound | Location |
| exonic | |||
| iFish Probablity | iFish Prediction | SIFT | Phylop |
| 0.5125 | deleterious | 0.135 | |
| Polyphen2_HDIV | Polyphen2_HVAR | MutationAssessor | GERP_RS |
| 1 | 0.896 | 1.465 | 4.37 |
| dScore | CpG | Hydropathicity | Polarity |
| 1.918 | 1 | 0 | |
| 79784 | MYH14 | 19 | 50783305 |
| Ref | Alt | Genotype | Validated Method |
| G | T | Mosaic | |
| SSC ID | WES Depth | WES Alt Count | PASM Depth |
| 13720.p1 | 215 | ||
| PASM Maf | PASM MAF 95%CI lowerbound | PASM MAF 95%CI upperbound | Location |
| exonic | |||
| iFish Probablity | iFish Prediction | SIFT | Phylop |
| 0.4875 | neutral | -0.297 | |
| Polyphen2_HDIV | Polyphen2_HVAR | MutationAssessor | GERP_RS |
| 0.002 | 0.013 | 0.28 | 0.994 |
| dScore | CpG | Hydropathicity | Polarity |
| 0.116 | 0 | 0.7 |
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes. At the same time, iFish alsoprovides functional annotations from other classifiers such as: SIFT, Polyphen2, and MutationTaster2.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.