View the Detailed Mosaic Information from PubMed ID: 28503910
| Gene ID | Gene Symbol | Chr | Position |
|---|---|---|---|
| 79981 | FRMD1 | 6 | 168462591 |
| Ref | Alt | Genotype | Validated Method |
| G | A | mosaic | PASM |
| SSC ID | WES Depth | WES Alt Count | PASM Depth |
| 11990.p1 | 32 | 7 | 2895 |
| PASM Maf | PASM MAF 95%CI lowerbound | PASM MAF 95%CI upperbound | Location |
| 0.08 | 0.07 | 0.091 | exonic |
| iFish Probablity | iFish Prediction | SIFT | Phylop |
| 0.0251 | neutral | 6.223 | |
| Polyphen2_HDIV | Polyphen2_HVAR | MutationAssessor | GERP_RS |
| 0.13 | 0.06 | 1.48 | |
| dScore | CpG | Hydropathicity | Polarity |
| 1.332 | 5.2 | -3.4 |
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes. At the same time, iFish alsoprovides functional annotations from other classifiers such as: SIFT, Polyphen2, and MutationTaster2.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.