View the Detailed Mosaic Information from PubMed ID: 26542245
| Gene ID | Gene Symbol | Chr | Position |
|---|---|---|---|
| 2475 | MTOR | 1 | 11190804 |
| Ref | Alt | Genotype | Validated Method |
| C | T | gonadal mosaic | |
| iFish Probablity | iFish Prediction | SIFT | Phylop |
| 0.9631 | deleterious | 0.15 | 7.447 |
| Polyphen2_HDIV | Polyphen2_HVAR | MutationAssessor | GERP_RS |
| 0.878 | 0.463 | 1.995 | 5.54 |
| dScore | CpG | Hydropathicity | Polarity |
| 0.644 | -0.4 | -1 |
Notes:
*iFish(Wang M, Wei L, PIMD: 27527004) is a supporting vector machine (SVM) based classifier which uses gene and gene family specific attributes. At the same time, iFish alsoprovides functional annotations from other classifiers such as: SIFT, Polyphen2, and MutationTaster2.
iFish utilized customized prediction cutoff for each classifier that maximizes the sum of sensitivity andspecificity.